UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C17E4.6	C17E4.6	0	chrI 9,426,826	contains similarity to Pfam domains PF05764 (YL1 nuclear protein) , PF08265 (YL1 nuclear protein C-terminal domain) contains similarity to Interpro domains IPR013272 (YL1 nuclear, C-terminal), IPR008895 (YL1 nuclear)
2	hda-2	C08B11.2	n/a	chrII 8,021,602	hda-2 encodes a Class I histone deacetylase; by homology, HDA-2 is predicted to function in deacetylation of histone residues and transcriptional regulation; loss of hda-2 activity via RNAi results in an increased spontaneous mutation rate, suggesting that hda-2 also plays a role in regulating genome stability.
3	B0511.2	B0511.2	n/a	chrI 10,651,985	contains similarity to Interpro domain IPR015804 (Cysteinyl-tRNA synthetase, class Ia, C-terminal)
4	sri-63	F39E9.3	n/a	chrII 3,288,198	C. elegans SRI-63 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003544 (Cytochrome c-type biogenesis protein CcmB)
5	C43H8.2	C43H8.2	n/a	chrI 10,623,645	contains similarity to Pfam domain PF09174 Maf1 regulator contains similarity to Interpro domains IPR017152 (RNA polymerase III transcriptional repressor, MAF1), IPR015257 (Maf1 regulator)
6	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	F13H6.5	F13H6.5	n/a	chrV 6,373,505	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
8	lin-46	R186.4	n/a	chrV 12,969,772	lin-46 encodes one of two C. elegans paralogs of bacterial MoeA proteins and mammalian gephyrins (E domain, only); LIN-46 is predicted to function as a scaffolding protein for a developmental timing complex, and may also play a role in molybdenum cofactor biosynthesis; identified in screens for suppressors of precocious heterochronic mutations in lin-14 and lin-28, lin-46 is required for stage-specific developmental events at the third larval and adult stages of development; as a component of the heterochronic pathway, lin-46 appears to act immediately downstream of lin-28, which encodes a predicted RNA binding protein required for cell fate specification at the L2 stage; a LIN-46:GFP fusion protein is detected in the cytoplasm and non-nucleolar part of the nucleus of ventral and lateral hypodermal cells around the time of the larval molts; in addition, the LIN-46 fusion protein is detected in cell bodies and axons of the AVBL/R motor interneurons.
9	nhr-59	T27B7.1	n/a	chrV 2,277,137	C. elegans NHR-59 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
10	C37C3.1	C37C3.1	n/a	chrV 7,858,917	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domains IPR012816 (Conserved hypothetical protein CHP02464), IPR005448 (Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit)
11	W01G7.4	W01G7.4	n/a	chrII 14,061,584	contains similarity to Danio rerio Protein SLC7A6OS (Solute carrier family 7 member 6 opposite strandstranscript homolog).; SW:Q5U3I2
12	Y48E1B.4	Y48E1B.4	n/a	chrII 13,562,596	contains similarity to Buchnera aphidicola Flagellar hook-length control protein.; SW:FLIK_BUCAP
13	F45C12.2	F45C12.2	n/a	chrII 1,732,740	contains similarity to Interpro domains IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
14	C26D10.3	C26D10.3	n/a	chrII 8,327,460	contains similarity to Pfam domain PF07992 Pyridine nucleotide-disulphide oxidoreductase contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000759 (Adrenodoxin reductase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
15	tag-50	M176.1	n/a	chrII 9,413,277	tag-50 encodes a predicted member of the arrestin family.
16	mcm-3	C25D7.6	n/a	chrV 15,058,134	mcm-3 encodes a member of the MCM2/3/5 family with similarity to human DNA replication licensing factor, MCM3, and affects embryonic viability.
17	K03B8.4	K03B8.4	n/a	chrV 11,394,932	contains similarity to Homo sapiens Isoform 2 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; ENSEMBL:ENSP00000349254
18	nud-2	R11A5.2	n/a	chrI 7,858,613	nud-2 encodes an ortholog of human NDE1 (OMIM:609449) and NDEL1 (OMIM:607538), effectors of LIS1 (OMIM:601545); NUD-2, along with other orthologs of LIS1-associated proteins (NUD-1, DHC-1, CDK-5, and CDKA-1), is required to prevent convulsions induced by exposure to the GABA antagonist pentylenetetrazole (PTZ); nud-2(RNAi), like RNAi of nud-1 et al., not only induces PTZ susceptibility but also causes GABA-containing synaptic vesicles in the ventral nerve cord to be distributed raggedly, and nud-2(RNAi) animals are abnormally susceptible to paralysis by the GABA agonist muscimol; nud-2(RNAi) phenotypes are dominantly enhanced by a heterozygous lis-1 allele, and nud-2(RNAi) delays the recovery from PTZ-induced paralysis of lis-1 heterozygotes.
19	T10C6.5	T10C6.5	n/a	chrV 16,023,741	contains similarity to Pfam domain PF04889 Cwf15/Cwc15 cell cycle control protein contains similarity to Interpro domain IPR006973 (Cwf15/Cwc15 cell cycle control protein)
20	F21H12.1	F21H12.1	n/a	chrII 6,098,704	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
21	C06A5.1	C06A5.1	n/a	chrI 6,017,022	contains similarity to Drosophila melanogaster Flybase gene name is CG3173-PA;; FLYBASE:CG3173
22	inx-7	K02B2.4	n/a	chrIV 5,945,314	C. elegans INX-7 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
23	K02F3.2	K02F3.2	n/a	chrIII 848,051	The K02F3.2 gene encodes a homolog of human SLC25A13, which when mutated leads to adult onset type II citrullinaemia (OMIM:603471).
24	grl-18	T05C3.4	n/a	chrV 5,487,265	grl-18 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
25	C07A4.1	C07A4.1	n/a	chrX 10,169,900	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
26	C14C11.4	C14C11.4	n/a	chrV 5,649,282	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
27	T07D1.5	T07D1.5	n/a	chrX 2,419,146
28	C49D10.10	C49D10.10	n/a	chrII 3,875,377	C49D10.10 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C49D10.10 has no clear orthologs in other organisms.
29	C27F2.7	C27F2.7	n/a	chrIII 4,982,522	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
30	Y106G6H.15	Y106G6H.15	n/a	chrI 10,473,965	contains similarity to Pfam domain PF07160 Protein of unknown function (DUF1395) contains similarity to Interpro domain IPR009829 (Protein of unknown function DUF1395)
31	fbxb-31	M151.5	n/a	chrII 3,638,541	C. elegans FBXB-31 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
32	VH15N14R.1	VH15N14R.1	n/a	chrI 7,781,895	contains similarity to Aspergillus niger Protein kinase C-like (EC 2.7.1.-).; SW:KPC1_ASPNG
33	K05C4.7	K05C4.7	n/a	chrI 14,738,206	contains similarity to Interpro domains IPR016617 (Uncharacterised conserved protein UCP013899, metal binding), IPR016024 (Armadillo-type fold)
34	hcf-1	C46A5.9	n/a	chrIV 7,772,495	C. elegans HCF-1 protein; contains similarity to Pfam domains PF01344 (Kelch motif) (3), PF00041 (Fibronectin type III domain) , PF07646 (Kelch motif) (4)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015915 (Kelch-type beta propeller)
35	C41H7.3	C41H7.3	n/a	chrII 3,006,666	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
36	abu-3	F31A3.1	n/a	chrX 17,553,848	abu-3 encodes a transmembrane protein with a predicted signal sequence, a glutamine/asparagine-rich domain and multiple cysteine-rich repeats (DUF139); abu-3 expression is induced by blockage of the unfolded-protein response in the endoplasmic reticulum (ER), and ABU-3 may function within the ER to protect the organism from damage by improperly folded nascent protein; abu-3 expression is enhanced in ER-stressed animals in which the unfolded protein response (UPR) is blocked by mutations in xbp-1, a bZIP transcription factor.
37	K10C2.6	K10C2.6	n/a	chrX 6,451,568
38	M199.2	M199.2	n/a	chrIV 15,109,806	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
39	rnp-3	K08D10.3	n/a	chrIV 4,175,171	rnp-3 encodes the small nuclear ribonucleoprotein (snRNP)-associated protein RNP-3/U2B''; genetically, rnp-3 appears to function redundantly with rnp-2/U1A: loss of rnp-3 activity alone results in low levels of embryonic and total lethality, while animals doubly mutant for rnp-3 and rnp-2/U1A show much higher levels of embryonic and total lethality; in addition, animals doubly mutant for SAP-1/U2A' and RNP-3/U2B'', display a much more severe phenotype than either single mutation, indicating that in vivo, these proteins have some independent functions; immunoprecipitation experiments indicate that RNP-3 associates with U2 RNA in vivo and that this association does not require the presence of SAP-1/U2A'.
40	T23E1.2	T23E1.2	n/a	chrIV 3,144,252
41	taf-6.1	W09B6.2	n/a	chrII 1,130,167	C. elegans TAF-6.1 protein; contains similarity to Pfam domains PF07571 (Protein of unknown function (DUF1546)) , PF02969 (TATA box binding protein associated factor (TAF)) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR004823 (TATA box binding protein associated factor (TAF)), IPR011442 (Protein of unknown function DUF1546)
42	C11E4.7	C11E4.7	n/a	chrX 9,617,962
43	srz-94	F49H6.11	n/a	chrV 17,034,553	C. elegans SRZ-94 protein ;
44	F23A7.4	F23A7.4	n/a	chrX 16,212,627	contains similarity to Mus musculus MKIAA0554 protein (Fragment).; TR:Q80TY0
45	dnj-23	T24H10.3	n/a	chrII 9,107,885	This gene encodes a protein containing a DnaJ ('J') domain.
46	F29D11.2	F29D11.2	n/a	chrI 7,637,136	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
47	Y57G7A.2	Y57G7A.2	n/a	chrII 1,296,418
48	let-60	ZK792.6	n/a	chrIV 11,689,627	let-60 encodes a member of the GTP-binding RAS protooncogene family; let-60 activity is required for viability, vulval development, spicule development, germ line meiotic progression, posterior development of the hypodermis, chemotaxis, sex myoblast migration, and muscle membrane extension; let-60 acts genetically downstream of let-23 with respect to vulval development and upstream of the MAPK pathway with respect to chemotaxis; let-60 is expressed in neural, muscle, and hypodermal lineages.
49	ZK686.4	ZK686.4	n/a	chrIII 7,769,518	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR007087 (Zinc finger, C2H2-type)
50	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)