UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T10C6.5	T10C6.5	1.9999999999999998e-86	chrV 16,023,741	contains similarity to Pfam domain PF04889 Cwf15/Cwc15 cell cycle control protein contains similarity to Interpro domain IPR006973 (Cwf15/Cwc15 cell cycle control protein)
2	F12F6.8	F12F6.8	n/a	chrIV 11,556,346	contains similarity to Schizosaccharomyces pombe Adenylate cyclase (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylylscyclase).; SW:CYAA_SCHPO
3	C49D10.10	C49D10.10	n/a	chrII 3,875,377	C49D10.10 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C49D10.10 has no clear orthologs in other organisms.
4	T23E1.2	T23E1.2	n/a	chrIV 3,144,252
5	F23A7.4	F23A7.4	n/a	chrX 16,212,627	contains similarity to Mus musculus MKIAA0554 protein (Fragment).; TR:Q80TY0
6	K02F3.2	K02F3.2	n/a	chrIII 848,051	The K02F3.2 gene encodes a homolog of human SLC25A13, which when mutated leads to adult onset type II citrullinaemia (OMIM:603471).
7	ZK686.4	ZK686.4	n/a	chrIII 7,769,518	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR007087 (Zinc finger, C2H2-type)
8	C24D10.4	C24D10.4	n/a	chrIV 5,160,919
9	Y53C12B.6	Y53C12B.6	n/a	chrII 9,723,099	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
10	rpb-4	F43E2.2	n/a	chrII 7,374,771	C. elegans RPB-4 protein; contains similarity to Pfam domain PF03874 RNA polymerase Rpb4 contains similarity to Interpro domains IPR010997 (HRDC-like), IPR005574 (RNA polymerase II, Rpb4), IPR006590 (RNA polymerase II, Rpb4, core)
11	M199.2	M199.2	n/a	chrIV 15,109,806	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
12	C18A3.2	C18A3.2	n/a	chrII 5,719,035	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
13	tag-50	M176.1	n/a	chrII 9,413,277	tag-50 encodes a predicted member of the arrestin family.
14	psa-4	F01G4.1	n/a	chrIV 11,128,568	The psa-4 (phasmid socket absent) gene encodes an ortholog of SWI2/SNF2, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; psa-4 is probably required during mitosis of the T cells for asymmetric cell division.
15	fbxb-49	K05F6.1	n/a	chrII 1,570,989	C. elegans FBXB-49 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
16	C17E4.6	C17E4.6	n/a	chrI 9,426,826	contains similarity to Pfam domains PF05764 (YL1 nuclear protein) , PF08265 (YL1 nuclear protein C-terminal domain) contains similarity to Interpro domains IPR013272 (YL1 nuclear, C-terminal), IPR008895 (YL1 nuclear)
17	pax-1	K07C11.1	n/a	chrV 8,225,481	C. elegans PAX-1 protein; contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
18	F56A6.4	F56A6.4	n/a	chrI 622,086
19	F41G3.2	F41G3.2	n/a	chrII 6,759,863
20	C41H7.4	C41H7.4	n/a	chrII 3,004,748	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
21	taf-4	R119.6	n/a	chrI 385,688	taf-4 encodes a TAFII (TBP(TATA-binding protein)-associated factor) that is orthologous to human TAF4 (hTAFII130); TAF-4 is predicted to be a component of the TFIID mRNA transcription complex and is generally required for early embryonic mRNA transcription; consistent with this observation, taf-4(RNAi) results in embryonic lethality at the ~100-cell stage with little cell differentiation, similar to the loss of AMA-1/RNA polymerase II activity; TAF-4 is detected in nuclei in the adult germline, oocytes, and embryo, from the 2-cell stage through early morphogenesis.
22	srt-1	C13B7.1	n/a	chrV 2,436,754	C. elegans SRT-1 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
23	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
24	Y48E1B.4	Y48E1B.4	n/a	chrII 13,562,596	contains similarity to Buchnera aphidicola Flagellar hook-length control protein.; SW:FLIK_BUCAP
25	flt-1	ZK783.4	n/a	chrIII 7,653,227	flt-1 encodes a putative homolog of flectin, an extracellular matrix protein thought to provide a microenvironment of great elasticity; however, FLT-1 protein contains no similarity to other ECM components, instead mostly appearing to be made up of chromatin or DNA-binding domains; FLT-1 also contains a glutamine/asparagine-rich domain, which may mediate epigenetic regulation.
26	T07D1.5	T07D1.5	n/a	chrX 2,419,146
27	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
28	F23F1.5	F23F1.5	n/a	chrII 30,845	contains similarity to Interpro domains IPR012310 (ATP dependent DNA ligase, central), IPR017336 (Snurportin-1), IPR002652 (Importin-alpha-like, importin-beta-binding region)
29	mdt-29	K08E3.8	n/a	chrIII 13,776,056	mdt-29 encodes a putative mediator subunit with a prion-like (asparagine- or glutamine-rich) domain; note that K08E3.8 is allegedly an ortholog of Drosophila INTERSEX/IX, but the actual C. elegans IX ortholog appears to be PQN-15); in yeast two-hybrid screens, MDT-29 interacts with SEL-7 and SEL-8; MDT-29 protein also self-associates; RNAi of K08E3.8 weakly enhances the two-anchor-cell phenotype of lin-12(ar170), roughly as much as sel-7 RNAi; since SEL-7 is a novel nuclear protein, MDT-29/SEL-7/SEL-8 is likely to form a nuclear complex formed in response to LIN-12 activation.
30	dpm-1	Y66H1A.2	n/a	chrIV 447,058	dpm-1 encodes a putative catalytic subunit of dolichol phosphate mannosyltransferase, orthologous to budding yeast and human DPM1 (OMIM:603503, mutated in congenital disorder of glycosylation type Ie); in mass RNAi assays, DPM-1 is required for embryonic viability and proper cortical motion in the early embryo.
31	mrt-2	Y41C4A.14	n/a	chrIII 11,748,489	mrt-2 encodes a highly conserved DNA-damage checkpoint protein homologous to the RAD1 protein found in S. pombe, Drosophila, and mammals; MRT-2 interacts with HUS-1 and HPR-9, also conserved DNA-damage checkpoint proteins, and is required in the germline for maintaining chromosomal integrity; mrt-2 mutations result in a failure to induce apoptosis in response to DNA damage, progressive telomere loss, chromosome fusion, and aneuploidy, all leading eventually to germline immortality.
32	B0511.2	B0511.2	n/a	chrI 10,651,985	contains similarity to Interpro domain IPR015804 (Cysteinyl-tRNA synthetase, class Ia, C-terminal)
33	Y54E5A.7	Y54E5A.7	n/a	chrI 14,713,042	contains similarity to Pfam domain PF00622 SPRY domain contains similarity to Interpro domains IPR001870 (B302, (SPRY)-like), IPR006594 (LisH dimerisation motif), IPR006595 (CTLH, C-terminal to LisH motif), IPR003877 (SPla/RYanodine receptor SPRY)
34	srt-63	T28A11.15	n/a	chrV 3,255,375	C. elegans SRT-63 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
35	Y57G7A.2	Y57G7A.2	n/a	chrII 1,296,418
36	ZC395.11	ZC395.11	n/a	chrIII 5,286,154
37	cdk-8	F39H11.3	n/a	chrI 8,704,132	cdk-8 encodes a member of the cyclin-dependent serine/threonine protein kinase family orthologous to human CDK8 (OMIM:603184) which functions in transcriptional regulation with the positive regulatory factor cyclin C, is associated with the RNA polymerase II holoenzyme, and may regulate gene-specific activators; CDK-8 also contains a glutamine/asparagine-rich domain; loss of cdk-8 function via RNA-mediated interference (RNAi) results in sterility in the injected hermaphrodite, suggesting that in C. elegans, CDK-8 may play a role in germ-line development.
38	K05F6.4	K05F6.4	n/a	chrII 1,544,461	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
39	fbxb-31	M151.5	n/a	chrII 3,638,541	C. elegans FBXB-31 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
40	btb-8	F45C12.6	n/a	chrII 1,723,449	C. elegans BTB-8 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
41	cin-4	ZK1127.7	n/a	chrII 7,039,709	C. elegans CIN-4 protein
42	C05E7.4	C05E7.4	n/a	chrX 12,966,891	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
43	T07F12.1	T07F12.1	n/a	chrX 4,895,096	T07F12.1 encodes a member of the histidine phosphatase superfamily orthologous to Bombyx mori ecdysteroid phosphate phosphatase (EPP), human STS1 (OMIM:609201) and human UBASH3A (OMIM:605736); in cell culture, recombinant T07F12.1 is a cytosolic enzyme with steroid phosphatase activity on ecdysone 22-phosphate (E22P), 3-epiecdysone 22-phosphate, 3-epiecdysone 2-phosphate substrates, and prednisolone 21-phosphate substrates, with E22P being preferred; T07F12.1 has no activity against 3-epiecdysone 3(alpha)-phosphate or 1-dehydrotestosterone sodium sulphate; unlike its Bombyx or mammalian orthologs, T07F12.1 lacks non-catalytic SH3 and UBA domains; T07F12.1 is paralogous to C. elegans C52E4.7, F09C12.8, F53B6.7, and F55A11.11.
44	T05A12.3	T05A12.3	n/a	chrIV 6,885,597	contains similarity to Cryptosporidium parvum Iowa II Large low complexity coiled coil protien with large repeat region.; TR:Q5CQL9
45	B0261.1	B0261.1	n/a	chrI 5,266,041	contains similarity to Pfam domain PF00249 Myb-like DNA-binding domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR014778 (Myb, DNA-binding), IPR009057 (Homeodomain-like)
46	W08F4.11	W08F4.11	n/a	chrII 593,637
47	B0454.9	B0454.9	n/a	chrII 3,053,483	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
48	nud-2	R11A5.2	n/a	chrI 7,858,613	nud-2 encodes an ortholog of human NDE1 (OMIM:609449) and NDEL1 (OMIM:607538), effectors of LIS1 (OMIM:601545); NUD-2, along with other orthologs of LIS1-associated proteins (NUD-1, DHC-1, CDK-5, and CDKA-1), is required to prevent convulsions induced by exposure to the GABA antagonist pentylenetetrazole (PTZ); nud-2(RNAi), like RNAi of nud-1 et al., not only induces PTZ susceptibility but also causes GABA-containing synaptic vesicles in the ventral nerve cord to be distributed raggedly, and nud-2(RNAi) animals are abnormally susceptible to paralysis by the GABA agonist muscimol; nud-2(RNAi) phenotypes are dominantly enhanced by a heterozygous lis-1 allele, and nud-2(RNAi) delays the recovery from PTZ-induced paralysis of lis-1 heterozygotes.
49	F49C12.12	F49C12.12	n/a	chrIV 9,320,583	contains similarity to Homo sapiens RNase K; VG:OTTHUMP00000182776
50	C17H11.5	C17H11.5	n/a	chrX 8,183,262