UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T10B11.4	T10B11.4	0	chrI 6,938,560
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C31E10.8	C31E10.8	n/a	chrX 14,007,275	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR011046 (WD40 repeat-like), IPR002011 (Receptor tyrosine kinase, class II, conserved site)
4	T09F5.1	T09F5.1	n/a	chrV 15,149,875	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
5	F26D11.4	F26D11.4	n/a	chrV 7,947,903
6	R12E2.8	R12E2.8	n/a	chrI 4,157,147	contains similarity to Galaxea fascicularis Galaxin.; TR:Q8I6S1
7	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
8	srh-46	T03F7.3	n/a	chrV 11,302,223	C. elegans SRH-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	W04A4.5	W04A4.5	n/a	chrI 13,669,210	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
10	str-135	F21F8.10	n/a	chrV 8,280,076	C. elegans STR-135 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	D1046.4	D1046.4	n/a	chrIV 8,935,680	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
12	str-73	F26D2.1	n/a	chrV 16,431,023	C. elegans STR-73 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	R11G1.2	R11G1.2	n/a	chrX 3,653,706
14	nth-1	R10E4.5	n/a	chrIII 4,292,462	C. elegans NTH-1 protein; contains similarity to Pfam domains PF00633 (Helix-hairpin-helix motif) , PF00730 (HhH-GPD superfamily base excision DNA repair protein) contains similarity to Interpro domains IPR011257 (DNA glycosylase), IPR003651 (Iron-sulphur cluster loop), IPR000445 (Helix-hairpin-helix motif), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR004036 (Endonuclease III, conserved site-2), IPR003265 (HhH-GPD)
15	aat-8	F28F9.4	n/a	chrIV 3,863,573	aat-8 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-8 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-8 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
16	srt-34	F54E2.6	n/a	chrV 2,817,549	C. elegans SRT-34 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	F36G9.13	F36G9.13	n/a	chrV 15,984,973	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003125 (Protein of unknown function WSN)
18	sago-1	K12B6.1	n/a	chrV 6,306,024	sago-1 encodes an Argonaute homolog that is partially required for the amplification phase of RNAi responses; a multiply mutant strain (MAGO), consisting of ppw-1(tm914), sago-1(tm1195), sago-2(tm894), F58G1.1(tm1019), C06A1.4(tm887), and M03D4.6(tm1144) alleles, is completely resistant to both germline and somatic RNAi; sago-1 is genetically redundant with ppw-1 and sago-2, with any one of these genes being able to transgenically partially restore the deficiency of MAGO worms; GFP-tagged SAGO-1 binds small secondary siRNAs produced by RNAi against GFP; MAGO is not transgenically rescued by rde-1; strains overexpressing GFP::SAGO-1 exhibited an enhanced level of RNAi overall, suggesting that SAGO-1 and its congeners are rate-limiting in vivo for RNAi.
19	epac-1	T20G5.5	n/a	chrIII 10,191,417	C. elegans EPAC-1 protein; contains similarity to Pfam domains PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin) , PF00027 (Cyclic nucleotide-binding domain) (2), PF00617 (RasGEF domain) , PF00618 (Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif) contains similarity to Interpro domains IPR008937 (Ras guanine nucleotide exchange factor), IPR011051 (Cupin, RmlC-type), IPR001895 (Guanine-nucleotide dissociation stimulator CDC25), IPR011991 (Winged helix repressor DNA-binding), IPR000595 (Cyclic nucleotide-binding), IPR002373 (cAMP/cGMP-dependent protein kinase), IPR014710 (RmlC-like jelly roll fold), IPR000651 (Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal), IPR000591 (Pleckstrin/ G-protein, interacting region)
20	acl-2	T06E8.1	n/a	chrV 10,029,692	T06E8.1 is orthologous to the human gene 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 2 (LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE, BETA) (AGPAT2; OMIM:603100), which when mutated leads to disease; T06E8.1 protein is predicted to be mitochondrial.
21	Y20C6A.3	Y20C6A.3	n/a	chrV 17,382,699	contains similarity to Saccharomyces cerevisiae Myo1 is a type II myosin, is localized to the actomyosin ring and is important for cytokinesis.; SGD:YHR023W
22	ZK593.8	ZK593.8	n/a	chrIV 10,938,663	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF02661 (Fic protein family) contains similarity to Interpro domains IPR003812 (Filamentation induced by cAMP protein Fic), IPR011990 (Tetratricopeptide-like helical), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
23	F39B2.7	F39B2.7	n/a	chrI 14,772,840	contains similarity to Pfam domain PF01926 GTPase of unknown function contains similarity to Interpro domains IPR005289 (GTP-binding), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR002917 (GTP-binding protein, HSR1-related), IPR003593 (AAA+ ATPase, core), IPR006073 (GTP1/OBG), IPR004520 (tRNA modification GTPase TrmE)
24	ttr-40	E02C12.4	n/a	chrV 9,354,969	C. elegans TTR-40 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
25	nhl-1	F54G8.4	n/a	chrIII 9,150,557	The nhl-1 gene encodes an RBCC protein, orthologous to the mammalian protein BERP; its C. elegans paralogs include ncl-1 and lin-41.
26	math-36	R52.8	n/a	chrII 2,118,724	C. elegans MATH-36 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
27	F25H9.3	F25H9.3	n/a	chrV 13,456,608	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
28	F56H1.5	F56H1.5	n/a	chrI 5,757,572	F56H1.5 encodes a putative ATP/ADP-activated metallocarboxypeptidase that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; F56H1.5 is orthologous to murine AGTPBP-1/Nna1/pcd (upregulated in damaged mouse spinal cord and mutated in Purkinje cell degeneration) and human AGTPBP1 (OMIM:606830); murine AGTPBP-1 is genetically required for tubulin carboxypeptidase activity in vivo, and F56H1.5's nearest paralog EEED8.6 has biochemical traits consistent with tubulin carboxypeptidase activity; F56H1.5 and its mammalian AGTPBP1 orthologs, along with other proteins, comprise a M14D3 peptidase subfamily.
29	C02G6.2	C02G6.2	n/a	chrV 5,873,482	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR001431 (Peptidase M16, zinc-binding site), IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
30	dct-12	Y57A10C.7	n/a	chrII 12,431,464	C. elegans DCT-12 protein ;
31	pme-2	E02H1.4	n/a	chrII 9,594,003	pme-2 encodes a poly(ADP-ribose) polymerase (PARP) orthologous to human PARP2 (OMIM:607725); PME-2 has a predicted C-terminal catalytic domain; PME-2 has PARP activity in vitro, which is blocked by mammalian PARP inhibitors; since these inhibitors also cause embryonic lethality in worms exposed to ionizing radiation, PME-1 is likely to be required in vivo for repairing broken DNA.
32	B0205.9	B0205.9	n/a	chrI 10,722,143	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
33	T22H6.1	T22H6.1	n/a	chrX 12,768,557	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
34	gcy-14	ZC412.2	n/a	chrV 14,865,514	gcy-14 encodes a predicted transmembrane guanylyl cyclase; the precise role of GCY-14 in C. elegans development and/or behavior is not yet known; however, by sequence similarity GCY-14 can be predicted to function in chemosensory signal transduction.
35	nhr-72	C17A2.8	n/a	chrII 3,849,882	C. elegans NHR-72 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	dcr-1	K12H4.8	n/a	chrIII 8,076,021	The dcr-1 gene encodes a bidentate ribonuclease that is homologous to E. coli RNAse III; dcr-1 is required both for RNA interference and for synthesis of small developmental RNAs; DCR-1 interacts in vivo with RDE-4, a double-stranded RNA (dsRNA) binding protein required for RNAi that interacts with trigger dsRNAs and may function to deliver dsRNAs to DCR-1 for endonucleolytic processing.
37	C48B4.8	C48B4.8	n/a	chrIII 9,560,470	contains similarity to Bacillus subtilis Hypothetical protein ywcE precursor.; SW:YWCE_BACSU
38	F14H3.4	F14H3.4	n/a	chrV 16,054,667	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
39	C31H5.1	C31H5.1	n/a	chrI 9,028,536	contains similarity to Pfam domain PF06342 Alpha/beta hydrolase of unknown function (DUF1057) contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR010463 (Protein of unknown function DUF1057, lipase putative)
40	F26E4.5	F26E4.5	n/a	chrI 9,769,984	F26E4.5 encodes an SH2 domain-containing tyrosine kinase related to the vertebrate FER non-receptor protein tyrosine kinase; loss of F26E4.5 activity in an RNAi-hypersensitive strain results in axon guidance defects indicating that F26E4.5 likely plays a role in regulation of axon navigation.
41	lgc-14	T01H10.2	n/a	chrX 12,112,417	C. elegans LGC-14 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
42	his-64	F22B3.1	n/a	chrIV 11,407,277	his-64 encodes an H4 histone.
43	wee-1.3	Y53C12A.1	n/a	chrII 9,715,024	C. elegans WEE-1.3 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
44	cyp-35B3	K07C6.2	n/a	chrV 3,946,183	C. elegans CYP-35B3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
45	ech-5	F56B3.5	n/a	chrIV 798,439	C. elegans ECH-5 protein; contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
46	tag-296	F49D11.9	n/a	chrI 10,934,755	C. elegans TAG-296 protein; contains similarity to Pfam domain PF08718 Glycolipid transfer protein (GLTP) contains similarity to Interpro domain IPR014830 (Glycolipid transfer protein, GLTP)
47	msp-152	ZK546.6	n/a	chrII 4,933,207	msp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
48	K11G9.3	K11G9.3	n/a	chrV 6,670,893	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
49	W09C3.1	W09C3.1	n/a	chrI 4,718,600	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
50	Y51B9A.4	Y51B9A.4	n/a	chrII 9,408,334	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)