UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	YMR084W	YMR084W	499	n/a	chrXIII 437,022	Putative protein of unknown function YMR084W and adjacent ORF YMR085W are merged in related strains
2	COX5A	YNL052W	499	n/a	chrXIV 531,955	Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth
3	YOL163W	YOL163W	499	n/a	chrXV 9,851	Putative protein of unknown function member of the Dal5p subfamily of the major facilitator family
4	GAL3	YDR009W	499	n/a	chrIV 464,215	Transcriptional regulator involved in activation of the GAL genes in response to galactose forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p binds galactose and ATP but does not have galactokinase activity
5	CDC26	YFR036W	499	n/a	chrVI 227,150	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
6	CUP2	YGL166W	499	n/a	chrVII 191,467	Copper-binding transcription factor activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations
7	ATP15	YPL271W	499	n/a	chrXVI 30,173	Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis phosphorylated
8	MDH2	YOL126C	499	0	chrXV 82,353	Cytoplasmic malate dehydrogenase, one of three isozymes that catalyze interconversion of malate and oxaloacetate involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds interacts with Pck1p and Fbp1
9	RPI1	YIL119C	499	n/a	chrIX 137,265	Putative transcriptional regulator overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation
10	DBP1	YPL119C	499	n/a	chrXVI 325,337	Putative ATP-dependent RNA helicase of the DEAD-box protein family mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs
11	DMC1	YER179W	499	n/a	chrV 548,969	Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes homolog of Rad51p and the bacterial RecA protein
12	POT1	YIL160C	499	n/a	chrIX 40,817	3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids
13	THI4	YGR144W	499	n/a	chrVII 780,889	Thiazole synthase, catalyzes formation of a thiazole intermediate during thiamine biosynthesis required for mitochondrial genome stability in response to DNA damaging agents
14	YKL050C	YKL050C	499	n/a	chrXI 344,236	Protein of unknown function the YKL050W protein is a target of the SCFCdc4 ubiquitin ligase complex and YKL050W transcription is regulated by Azf1p
15	MCH2	YKL221W	499	n/a	chrXI 6,817	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane mutant is not deficient in monocarboxylate transport
16	FLO10	YKR102W	499	n/a	chrXI 648,110	Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation
17	SMP1	YBR182C	499	n/a	chrII 594,185	Putative transcription factor involved in regulating the response to osmotic stress member of the MADS-box family of transcription factors
18	THI2	YBR240C	499	n/a	chrII 701,166	Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes
19	YHR033W	YHR033W	499	n/a	chrVIII 176,183	Putative protein of unknown function epitope-tagged protein localizes to the cytoplasm
20	WSC4	YHL028W	499	n/a	chrVIII 49,671	ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane may also have a role in the stress response but has only partial functional overlap with WSC1-3
21	ALP1	YNL270C	499	n/a	chrXIV 136,800	Arginine transporter expression is normally very low and it is unclear what conditions would induce significant expression
22	CAT8	YMR280C	499	n/a	chrXIII 829,178	Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements
23	FAA2	YER015W	499	n/a	chrV 185,658	Medium chain fatty acyl-CoA synthetase, activates imported fatty acids accepts a wide range of fatty acid chain lengths with a preference for medium chains, C9:0-C13:0 localized to the peroxisome
24	SEO1	YAL067C	499	n/a	chrI 8,125	Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily mutation confers resistance to ethionine sulfoxide
25	YNR073C	YNR073C	499	n/a	chrXIV 775,546	Putative mannitol dehydrogenase
26	DOT6	YER088C	499	n/a	chrV 334,182	Protein involved in rRNA and ribosome biogenesis binds polymerase A and C motif subunit of the RPD3L histone deacetylase complex similar to Tod6p has chromatin specific SANT domain involved in telomeric gene silencing and filamentation
27	NDE1	YMR145C	499	n/a	chrXIII 555,634	Mitochondrial external NADH dehydrogenase, a type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain
28	CAT5	YOR125C	499	n/a	chrXV 559,380	Protein required for ubiquinone (Coenzyme Q) biosynthesis localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes required for gluconeogenic gene activation
29	SPR3	YGR059W	499	n/a	chrVII 608,332	Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes septin protein involved in sporulation regulated by ABFI
30	SSU1	YPL092W	499	n/a	chrXVI 374,481	Plasma membrane sulfite pump involved in sulfite metabolism and required for efficient sulfite efflux major facilitator superfamily protein
31	AGP3	YFL055W	499	n/a	chrVI 17,842	Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions transcription is induced under conditions of sulfur limitation plays a role in regulating Ty1 transposition
32	DAK2	YFL053W	499	n/a	chrVI 24,310	Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA) involved in stress adaptation
33	YFL052W	YFL052W	499	n/a	chrVI 28,930	Putative zinc cluster protein that contains a DNA binding domain null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity
34	YFL051C	YFL051C	499	n/a	chrVI 30,299	Putative protein of unknown function YFL051C is not an essential gene
35	HXT10	YFL011W	499	n/a	chrVI 113,165	Putative hexose transporter, expressed at low levels and expression is repressed by glucose
36	ROG3	YFR022W	499	n/a	chrVI 197,933	Protein that binds the ubiquitin ligase Rsp5p via its 2 PY motifs has similarity to Rod1p mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant proposed to regulate the endocytosis of plasma membrane proteins
37	ULI1	YFR026C	499	n/a	chrVI 206,002	Putative protein of unknown function involved in and induced by the endoplasmic reticulum unfolded protein response
38	YJL160C	YJL160C	499	n/a	chrX 118,393	Putative protein of unknown function member of the PIR (proteins with internal repeats) family of cell wall proteins non-essential gene that is required for sporulation mRNA is weakly cell cycle regulated, peaking in mitosis
39	PGU1	YJR153W	499	n/a	chrX 723,357	Endo-polygalacturonase, pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins
40	AMA1	YGR225W	499	n/a	chrVII 946,082	Activator of meiotic anaphase promoting complex (APC/C) Cdc20p family member required for initiation of spore wall assembly required for Clb1p degradation during meiosis
41	KNH1	YDL049C	499	n/a	chrIV 365,471	Protein with similarity to Kre9p, which is involved in cell wall beta 1,6-glucan synthesis overproduction suppresses growth defects of a kre9 null mutant required for propionic acid resistance
42	MRK1	YDL079C	499	n/a	chrIV 313,849	Glycogen synthase kinase 3 (GSK-3) homolog one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation
43	MAL11	YGR289C	499	n/a	chrVII 1,074,888	Inducible high-affinity maltose transporter (alpha-glucoside transporter) encoded in the MAL1 complex locus broad substrate specificity that includes maltotriose required for isomaltose utilization
44	MGA1	YGR249W	499	n/a	chrVII 988,734	Protein similar to heat shock transcription factor multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
45	RRT6	YGL146C	499	n/a	chrVII 229,218	Putative protein of unknown function non-essential gene identified in a screen for mutants with increased levels of rDNA transcription contains two putative transmembrane spans, but no significant homology to other known proteins
46	MAL12	YGR292W	499	n/a	chrVII 1,077,476	Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism encoded in the MAL1 complex locus hydrolyzes the disaccharides maltose, turanose, maltotriose, and sucrose
47	BSC5	YNR069C	499	n/a	chrXIV 761,857	Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
48	PDR18	YNR070W	499	n/a	chrXIV 767,375	Putative transporter of the ATP-binding cassette (ABC) family, implicated in pleiotropic drug resistance the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
49	YNR071C	YNR071C	499	n/a	chrXIV 770,954	Putative protein of unknown function
50	SNZ2	YNL333W	499	n/a	chrXIV 13,715	Member of a stationary phase-induced gene family transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner forms a coregulated gene pair with SNO2 interacts with Thi11p