UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	his-47	B0035.7	9.999999999999999e-43	chrIV 11,324,148	his-47 encodes an H2A histone; by homology, HIS-47 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-47 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
2	F56G4.4	F56G4.4	n/a	chrI 11,377,362	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR000533 (Tropomyosin), IPR001202 (WW/Rsp5/WWP)
3	srw-121	K12D9.3	n/a	chrV 2,990,948	C. elegans SRW-121 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
4	C28A5.2	C28A5.2	n/a	chrIII 4,437,117	contains similarity to Interpro domain IPR001564 (Nucleoside diphosphate kinase)
5	dpf-2	C27C12.7	n/a	chrX 14,834,928	C. elegans DPF-2 protein; contains similarity to Pfam domains PF00930 (Dipeptidyl peptidase IV (DPP IV) N-terminal region) , PF00326 (Prolyl oligopeptidase family) contains similarity to Interpro domains IPR001375 (Peptidase S9, prolyl oligopeptidase active site region), IPR002469 (Peptidase S9B, dipeptidylpeptidase IV N-terminal)
6	his-62	F55G1.3	n/a	chrIV 7,486,714	his-62 encodes an H2B histone.
7	hcf-1	C46A5.9	n/a	chrIV 7,772,495	C. elegans HCF-1 protein; contains similarity to Pfam domains PF01344 (Kelch motif) (3), PF00041 (Fibronectin type III domain) , PF07646 (Kelch motif) (4)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015915 (Kelch-type beta propeller)
8	his-63	F22B3.2	n/a	chrIV 11,406,611	his-63 encodes an H3 histone; by homology, HIS-63 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-63 is a replication-dependent histone locus.
9	ced-12	Y106G6E.5	n/a	chrI 10,224,961	ced-12 is required both for phagocytotic engulfment of dying (apoptotic) cells, and for normal migrations of healthy cells during development.
10	F22F7.4	F22F7.4	n/a	chrV 2,104,867	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
11	wve-1	R06C1.3	n/a	chrI 11,927,136	wve-1 encodes a homolog of the mammalian WAVE protein; based on homology WVE-1 might be involved in actin cytoskeletal dynamics; wve-1 is required for early cell migrations in the epidermis during embryonic morphogenesis and may require gex-2 and gex-3 for its function.
12	R05F9.11	R05F9.11	n/a	chrII 4,913,028
13	C41D11.1	C41D11.1	n/a	chrI 4,458,028
14	K11E4.2	K11E4.2	n/a	chrX 13,718,299	contains similarity to Pfam domain PF00017 SH2 domain contains similarity to Interpro domains IPR006020 (Phosphotyrosine interaction region), IPR000980 (SH2 motif)
15	C01H6.9	C01H6.9	n/a	chrI 7,231,276	C01H6.9 encodes a homolog of haploid germ cell-specific nuclear protein kinase (haspin) that specifically binds GOA-1 in yeast two-hybrid assays; C01H6.9 is expressed in PHB sensory neurons and PVT interneurons in the tail, several unidentified neurons in the head (with projections to the nose and nerve ring), and intestinal cells, with mainly nuclear localization; C01H6.9 has no obvious function or phenotype in RNAi assays, either alone or with inactivation of a close paralog (F22H10.5).
16	tag-189	T04A8.12	n/a	chrIII 4,706,131	C. elegans TAG-189 protein ; contains similarity to Cricetulus griseus Post-GPI-attachment to proteins 2.; TR:Q2ABP2
17	efl-1	Y102A5C.18	n/a	chrV 16,962,099	efl-1 encodes a homolog of mammalian E2F that is required for embryonic asymmetry and that functions as a transcriptional repressor; during vulval development, efl-1, a class B synMuv gene, acts with class B synMuv genes dpl-1 and lin-35/Rb to antagonize receptor tyrosine kinase and Ras-mediated signaling; EFL-1 also negatively regulates the G1 to S phase cell cycle transition.
18	osm-11	F11C7.5	n/a	chrX 17,420,817	C. elegans OSM-11 protein ;
19	D2096.1	D2096.1	n/a	chrIV 8,397,532	contains similarity to Pfam domain PF02466 Tim17/Tim22/Tim23 family contains similarity to Interpro domain IPR003397 (Mitochondrial import inner membrane translocase, subunit Tim17/22)
20	F10E7.11	F10E7.11	n/a	chrII 7,121,124	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR000949 (ELM2)
21	F25H5.5	F25H5.5	n/a	chrI 9,161,573	F25H5.5 encodes the C. elegans homologue of Claspin, an S-phase checkpoint component that interacts with Chk1 and negatively regulates cell cycle progression; in wild-type animals, loss of F25H5.5 activity results in some embryonic lethality; loss of F25H5.5 activity in a lin-35 mutant background, however, results in sterility, as well as smaller than normal body size, uncoordinated locomotion, and a protruding vulva; weaker F25H5.5 RNAi phenotypes are seen in lin-15B and eri-1; lin-15B backgrounds.
22	srj-4	C27A7.7	n/a	chrV 12,163,847	C. elegans SRJ-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	pqn-51	K11D12.2	n/a	chrV 5,050,974	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
24	C01F6.9	C01F6.9	n/a	chrIV 9,095,971	The C01F6.9 gene resides in an operon that also contains the genes icl-1 and lpl-1.
25	C10A4.2	C10A4.2	n/a	chrX 7,412,571
26	fbxa-200	T07D3.1	n/a	chrII 905,248	C. elegans FBXA-200 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
27	T02G5.1	T02G5.1	n/a	chrII 7,098,996
28	glb-18	F52A8.4	n/a	chrI 7,344,423	glb-18 encodes a globin; glb-18 is expressed in larval and adult neurons and excretory gland cells, and in adult spermetheca and vulva; glb-18 transcription is higher in L3 and dauers than in young adults; glb-18 has no obvious function in mass RNAi assays.
29	K10D11.2	K10D11.2	n/a	chrIV 12,980,447	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
30	secs-1	D1054.13	n/a	chrV 10,803,314	C. elegans SECS-1 protein; contains similarity to Pfam domain PF05889 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) contains similarity to Interpro domains IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR008829 (Soluble liver antigen/liver pancreas antigen)
31	F56A6.4	F56A6.4	n/a	chrI 622,086
32	mes-2	R06A4.7	n/a	chrII 14,386,115	mes-2 encodes a SET domain-containing protein that is orthologous to the Drosophila Polycomb group protein Enhancer of zeste [E(Z)]; as a member of a Polycomb-like chromatin repressive complex with MES-3 and MES-6, MES-2 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; in addition, MES-2 activity is required for normal levels and localization of MES-3 in >24-cell-stage embryos; MES-2 expression is detected in the primordial germ cells and germline nuclei throughout development, in all nuclei in early embryos, and in somatic nuclei, including those of the male tail, in L2 and L3 larvae; in the nucleus, MES-2 appears to localize to chromatin.
33	his-60	F55G1.11	n/a	chrIV 7,487,766	his-60 encodes an H4 histone; by homology, HIS-60 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-60 expression is detected in early embryos, beginning at the 28-cell stage and continuing through the comma stage (early morphogenesis); his-60 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
34	C08F11.1	C08F11.1	n/a	chrIV 13,624,656	contains similarity to Coxiella burnetii Hypothetical protein.; TR:Q83D43
35	H25P19.1	H25P19.1	n/a	chrV 688,859
36	Y48A5A.1	Y48A5A.1	n/a	chrIV 1,967,552	contains similarity to Pfam domain PF04925 SHQ1 protein contains similarity to Interpro domain IPR007009 (SHQ1 protein)
37	lips-17	R07G3.2	n/a	chrII 7,609,466	C. elegans LIPS-17 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domains IPR002918 (Lipase, class 2), IPR008262 (Lipase, active site)
38	M03C11.2	M03C11.2	n/a	chrIII 10,402,129	contains similarity to Pfam domain PF06733 DEAD_2 contains similarity to Interpro domains IPR014013 (Helicase, superfamily 1 and 2, ATP-binding, DinG/Rad3-type), IPR010614 (DEAD2), IPR006554 (Helicase-like, DEXD box c2 type), IPR006555 (Helicase, ATP-dependent, c2 type), IPR014001 (DEAD-like helicase, N-terminal), IPR013020 (DNA helicase (DNA repair), Rad3 type)
39	math-37	R52.9	n/a	chrII 2,121,460	C. elegans MATH-37 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
40	C25D7.10	C25D7.10	n/a	chrV 15,067,993	contains similarity to Mus musculus Probable taste receptor type 2 member 23 (T2R23) (STC9-2).; SW:T2R2_MOUSE
41	F31F4.1	F31F4.1	n/a	chrV 685,113	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
42	his-44	F08G2.1	n/a	chrII 13,826,823	his-44 encodes an H2B histone.
43	srx-53	T27C5.2	n/a	chrV 17,400,916	C. elegans SRX-53 protein; contains similarity to Interpro domain IPR010989 (t-SNARE)
44	F43G9.10	F43G9.10	n/a	chrI 8,639,367	contains similarity to Pfam domain PF06991 Micro-fibrillar-associated protein 1 C-terminus contains similarity to Interpro domains IPR009730 (Micro-fibrillar-associated 1, C-terminal), IPR000533 (Tropomyosin)
45	K02E7.2	K02E7.2	n/a	chrII 1,080,452
46	duo-3	Y106G6H.12	n/a	chrI 10,467,681	C. elegans DUO-3 protein; contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02338 (OTU-like cysteine protease) contains similarity to Interpro domains IPR003323 (Ovarian tumour, otubain), IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
47	taf-6.1	W09B6.2	n/a	chrII 1,130,167	C. elegans TAF-6.1 protein; contains similarity to Pfam domains PF07571 (Protein of unknown function (DUF1546)) , PF02969 (TATA box binding protein associated factor (TAF)) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR004823 (TATA box binding protein associated factor (TAF)), IPR011442 (Protein of unknown function DUF1546)
48	srd-2	R05H5.1	n/a	chrII 10,186,817	C. elegans SRD-2 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
49	F26F4.6	F26F4.6	n/a	chrIII 4,892,477	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
50	F56G4.6	F56G4.6	n/a	chrI 11,369,184	contains similarity to Interpro domain IPR001623 (Heat shock protein DnaJ, N-terminal)