Affine Alignment
 
Alignment between CYP2C9 (top ENST00000260682.8 490aa) and CYP2D6 (bottom ENST00000645361.2 497aa) score 16891

001 MDSLVVLVLCLSCLLLL--SLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLS 058
    +++|| | + ++  |||   + |+     + |||| ||| +||+| +  ++       | 
003 LEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLR 062

059 KVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERAN---RGFGIVFS 115
    + +| ||+|     |+|||+|  ||+|||+  ||+ + |   |+ +      |  |+  +
063 RRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLA 122

116 N-GKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAP 174
      |  |+| ||||+ |||| |+||+|+|  | ||| ||          |  |  +|  | 
123 RYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAV 182

175 CNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLL 234
     ||| |+   +||+| | +|| |++   | +|   | +++   |  |++ + |    |+|
183 SNVIASLTCGRRFEYDDPRFLRLLDLAQEGLK-EESGFLREVLNAVPVLLHIPALAGKVL 241

235 KNVAFMKSYIL---EKVKEHQESMD-MNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENT 290
    +   | |+++    | + ||+ + |    |+|  + || +||| | |  | |  |+|   
242 R---FQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIV 298

291 AVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDA 350
      ||| ||  |||||| + |||++ ||+|  +||+||+ |||+ | | | |++||||| |
299 VADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTA 358

351 VVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPH 410
    |+|||||+ |++|  + |  + ||+ + + ||||||++ +|+||| |   +  |  | | 
359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418

411 HFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTT 470
    ||||  |+| | + |+|||||+| |+|| || |||||| ||+||+|+  |+   +   + 
419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSF-SVPTGQPRPSH 477

471 PVVNGFASVPPFYQLCFIP 489
      |  |   |  |+|| +|
478 HGVFAFLVSPSPYELCAVP 496