Alignment between NOTCH3 (top ENST00000263388.7 2321aa) and JAG1 (bottom ENST00000254958.10 1218aa) score 26182

0140 GRFLC------SCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPL 0193
     | + |      +|  |+ |  |   +  || |   +||   |  ||   |+|  |+ |  
0208 GHYACDQNGNKTCMEGWMGPECNRAI--CRQGCSPKHGSCKL--PGD--CRCQYGWQGLY 0261

0194 CENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR-CLNGGTCV 0252
     |+     | | |    | | +     + | |   + || |+ +++ |  |+ ||||||| 
0262 CDK----CIPHPGCVHGICNE----PWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCS 0313

0253 D-GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESC 0311
     + | + | | ||  ++|  |      |   |  ||| |+|  |  |  | |  |||| +|
0314 NTGPDKYQCSCPEGYSGPNCEIAEHACLSDP--CHNRGSCKETSLGFECECSPGWTGPTC 0371

0312 SQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPV 0371
     | |||||+   | || || | |  |                                   
0372 STNIDDCSPNNCSHGGTCQDLVNGFK---------------------------------- 0397

0372 NGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETD 0431
          | ||| +||  |  | +||   | || +   | |   |+ | |  |+ |  |+ +
0398 -----CVCPPQWTGKTCQLDANECE--AKPCVNAKSCKNLIASYYCDCLPGWMGQNCDIN 0450

0432 VNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGF 0491
     +|+|| | |+| |+| | +  + |||  |+ | +|| ||||| |+||+||| |++ +| |
0451 INDCL-GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF 0509

0492 SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSP 0551
      | ||+||||+ ||||+| |   ||+|||+| ++   | |+| | +||  |    | |  
0510 QCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRT 0569

0552 DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLV-DKYLCRCPS 0610
      ||     +|     ||  |     |     |    |  |   |||      |+ | |  
0570 TPC---EVID-----SCTVAMASNDT--PEGVRYISSNVCGPHGKCKSQSGGKFTCDCNK 0619

0611 GTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEG 0669
     | ||  |  ||+|| ||||   | | ||+| | |+|  |+ |  |   ||+|+ +||  |
0620 GFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNG 0679

0670 GSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRC 0729
     |+| |  |                                      | | |+ || |  |
0680 GTCRDLVN-------------------------------------DFYCDCKNGWKGKTC 0702

0730 SQSLARDA-CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL--SPCTPNPCEHGGRC 0786
         +||+ |+   |  ||||  +|  | | || | +|  | +   | | |||| +|| |
0703 H---SRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTC 0759

0787 ESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSC 0846
         |+                                       ||+| |  |+ || |
0760 -VVNGE---------------------------------------SFTCVCKEGWEGPIC 0779

0847 DQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHV 0905
      |+ ||| |+|| | |+| ||   + | | |||||| |  +++|| |+||  | || | +
0780 AQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEI 0839

0906 ASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP 0965
       + | ||||+ |  |+    + |   |   |+ +               ||    + + 
0840 NGYRCVCPPGHSGAKCQ----EVSGRPCITMGSVIP-------------DGAKWDDDCNT 0882

0966 CLSRPCLHGGV-CSAAHPGFRCTCL------ESFTGPQC-QTLVDWCSRQPCQNGGRC 1015
     |    ||+| + ||    | |  ||      |  +|  |   | | |   ||   | |
0883 C---QCLNGRIACSKVWCGPR-PCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGEC 0936