Affine Alignment
 
Alignment between MCM2 (top ENST00000265056.12 904aa) and ENSG00000286235 (bottom ENST00000652720.1 1009aa) score 15276

125 GRGLGRMR---------RGLLYDSDEEDEERPARKRRQVERATEDGEE-------DEEMI 168
    ||| || |          |       | | ||   +   +| +|   +        + | 
007 GRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTKTPQSMQ 066

169 ESIENLEDLKGHSV--REWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKEN 226
     +++     ||  +   |  | + | +|    |+ |   |+| +     |+ |     | 
067 STLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYD----KDEI-----ER 117

227 RESLVVNYEDLAAREHV------LAYFLPEAPAELLQIFDEAALEVV-------LAMYPK 273
    + |++|++++|     |      +|  | +|| + |     |  +|+        |    
118 KGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQA 177

274 YDRITN---------HIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSM 324
     + ++|         ||| |+ +   + +|+++|  +  + |   | |   + + |  + 
178 QEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTK 237

325 VKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEE---TIYQNYQRIRIQE- 380
    + + |  |  +   |     +   |  ||     |     +     |+  ++| |+||| 
238 MAFLCAACGEIQS-FPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQEL 296

381 -SPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGI--YHNNYDGSLNTANGFPVFAT 437
     |  +  |||+||+ +  |+ |||||| ||| + +|||    |  +|| |  |   +|  
297 MSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRN-KNDKCMFLL 355

438 VILANHVA-KKDNKV----------AVGELTDEDVKMITSLSKDQQIGEKIFASIAPSIY 486
     | || ++  |  |            + | + +|+  |  +  ++ + + |  |+ | |+
356 YIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIF 415

487 GHEDIKRGLALALFGGEPKNPGGKHK--VRGDINVLLCGDPGTAKSQFLKYIEKVSSRAI 544
    ||| +| |||||||||  |    |++  +||| ++|+ ||||  ||| |+    |+ | +
416 GHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGV 475

545 FTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAM 604
    +  |   +  |||  + +   | ++ |||||||| |+|+| ||||||| +| + ++ |||
476 YVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAM 534

605 EQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVR 664
    ||||||++|||+| || || ++||||||+|| |+ + | |||+ +   ++||||++ ++ 
535 EQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILL 594

665 DTVDPVQDEMLARFVVG--------------SHVRHHPSNKEEEGLANGSAAEPAMPNTY 710
    || +   | +|+  |+               + +    ||     + +       +    
595 DTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVP 654

711 G--VEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIE 768
    |  ++|+| ++|+||| ||++ |+|+|+      +   | +|||+|    | ||| | +|
655 GETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLE 714

769 SMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDT 805
    |+||+ || ||+ ||+   ++|    + +|  | + |
715 SLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGT 751