Affine Alignment
 
Alignment between ARHGEF25 (top ENST00000286494.9 580aa) and ARHGEF17 (bottom ENST00000263674.4 2063aa) score 3230

0131 PGDKTQPPEEETLSQAPESEEE-QKKKALERSMYVLSELVETEKMYVDDLGQIVEGYMAT 0189
     |  + +|||    +  |    +   |  ++   +|   |++||+ ||+ |  +++|||  
1036 PSAEAKPPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQP 1095

0190 MAAQGVPESLRGRDRI----VFGNIQQIYEWHRDYFLQELQRCLKDPDW---------LA 0236
     +     ||+    |      +|  | ++ | | + ||++++ |++   |         | 
1096 LKQ---PENSVLCDPSLVDEIFDQIPELLE-HHEQFLEQVRHCMQ--TWHAQQKVGALLV 1149

0237 QLFIKHERRLHMYVVYCQ---NKPKSEHVVSEFGDSYFEELRQQLGHRLQ---LNDLLIK 0290
     | | | +  +++|  |     |   +  |  |   ++ + | | +    +   |+||+||
1150 QSFSK-DVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIK 1208

0291 PVQRIMKYQLLLKDFLKYYNRAGMDTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLT 0350
     ||||| +|+||+|| ||+      |   | +|   +  | +| |           +|  +
1209 PVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERIN-----------KGVRS 1257

0351 AQGKLLGQDTFWVTEPEAGGLLSSRGRERRVFLFEQIIIFSEALGG 0396
     |+            |    |+   +   || || ++++|  +|+||
1258 AEEAERHARVLQEIEAHIEGMEDLQAPLRR-FLRQEMVIEVKAIGG 1302