Alignment between SMC4 (top ENST00000357388.8 1288aa) and SMC6 (bottom ENST00000448223.7 1091aa) score 4826

0091 NFKSYAGEKILGPFH--KRFSCIIGPNGSGKSNVIDSMLFVFGYRAQKI-RSKKLSVLIH 0147
     + |++    +||||      + ++| |||||| |+ +++   | ||    |   |   + 
0052 HLKNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGRAVATNRGSSLKGFVK 0111

0148 NSDEHKDIQSCTVEVHFQKIIDKEGDDYEVIPNSNFYVSRTACRDNTSVYHISGKKKTFK 0207
     +     || | |+           |||                    |||          
0112 DGQNSADI-SITLR--------NRGDD----------------AFKASVY---------- 0136

0208 DVGN--LLRSHGIDLDHNRFLILQGEVEQIAMMKPKGQTEHDEGMLEYLEDIIGCGRLNE 0265
       ||  |++ | | +| +|   |+     +   +     |    +|++        +++ 
0137 --GNSILIQQH-ISIDGSRSYKLKSATGSVVSTR----KEELIAILDHFNI-----QVDN 0184

0266 PIKVLCRRVE---ILNEHRGEKLNRVKMVEKEKDALEGEKNIAIEFLTLENEIFRKKNHV 0322
     |+ || + +    + +++ |+|  +  |   + + ++ + +  +|      |  +++ | 
0185 PVSVLTQEMSKQFLQSKNEGDKY-KFFMKATQLEQMKEDYSYIME----TKERTKEQIHQ 0239

0323 CQYYIYELQKRIAEMETQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKF 0382
      +  + ||+++  | |   |+          |+|+ | + +     | + ||+|| |   
0240 GEERLTELKRQCVEKE---ERFQSIAGLSTMKTNLESLKHEMAWAVVNEIEKQLNAIRDN 0296

0383 IEENKEKFTQLD--LEDVQVREKLKHATSKAKKLEKQLQKDKEKVE-------EFKSIPA 0433
     |+  +++  +||  +|+ |||  |  |  | | ++ +|+|  |+           |+   
0297 IKIGEDRAARLDRKMEEQQVR--LNEAEQKYKDIQDKLEKISEETNARAPECMALKADVV 0354

0434 KSNNIINET-TTRNNALEKEK--EKEEKKLKEVMDSLKQET-QGLQKEKESREKELMGFS 0489
           ||     | +| + |  +|++++| + ++ ||+ | | |+ |+  |+|++    
0355 AKKRAYNEAEVLYNRSLNEYKALKKDDEQLCKRIEELKKSTDQSLEPERLERQKKISWLK 0414

0490 KSVNEARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAASETLKERKAAIRDIEGKLP 0549
     + |                + ++ |+   ++ + ++|+    |   + |    |++  | 
0415 ERVK--------------AFQNQENSVNQEIEQFQQAIEKDKEEHGKIKREELDVKHALS 0460

0550 QTEQELKE-KEKELQKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKK 0608
       +++||| |+ +  +| +   |  +|                        |+||    +
0461 YNQRQLKELKDSKTDRLKRFGPNVPAL------------------------LEAIDDAYR 0496

0609 SGRIPGIYGRLGDLGAI----DEKYDVAISSCCHALDYIVVDSIDIAQECVNFLKRQNIG 0664
      |     |  +| |||     | +  +|| ||   |          |  | |    + + 
0497 QGHF--TYKPVGPLGACIHLRDPELALAIESCLKGLLQ--------AYCCHNHADERVLQ 0546

0665 VATFIGLDKMAVWAKKMTEIQTPENTPRLFDLVKVKDEKIRQAFYFALRDTLVADNLDQA 0724
           + +  +       |   |    ++|+      + | |++      | |  +| |
0547 AL----MKRFYLPGTSRPPIIVSEFRNEIYDV------RHRAAYHPDFPTVLTALEIDNA 0596

0725 TRVAYQKDRRW--RVVTLQGQIIEQS------------GTMTGGGSKVMKGRMGSS---- 0766
            | |    |+ ++   + ++               |  | +|  ||  ||    
0597 VVANSLIDMRGIETVLLIKNNSVARAVMQSQKPPKNCREAFTADGDQVFAGRYYSSENTR 0656

0767 --LVIEISEEEVNKMESQLQNDSKKAMQIQEQKVQLEERVVKLRHSE----------REM 0814
        +    + |++ +|++++| + + + +|+    ||+    ++|+|          +|+
0657 PKFLSRDVDSEISDLENEVENKTAQILNLQQHLSALEK---DIKHNEELLKRCQLHYKEL 0713

0815 RNTLEKFTASIQRLIEQEEYLNVQVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVA 0874
     +  + |  + |+ |   ||+ +| +  ||        +| | |++||++   |   + + 
0714 KMKIRKNISEIRELENIEEHQSVDIATLEDE---AQENKSKMKMVEEHMEQQKENMEHL- 0769

0875 EKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNL 0934
      |+ |+||| |       +    |+    +  | +  +|+   | +   +   +  +   
0770 -KSLKIEAENK------YDAIKFKINQLSELADPLKDELNLADSEVDNQKRGKRHYEEKQ 0822

0935 QKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLL 0994
     ++  |++ + ++|+   |||+++  ++ + +  +  ||       |+|   + ||   | 
0823 KEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEV-------EKSASILDKEINRLR 0875

0995 QELKVIQENEHALQKDALSIKLKLEQIDGHIAEHNSKIKYWHKEISKISLHPIEDNPIEE 1054
     |+++     |||   |   |  + ++      + +||++   | |               
0876 QKIQA----EHASHGDREEIMRQYQEARETYLDLDSKVRTLKKFIKL------------- 0918

1055 ISVLSPEDLEAIKNPDSITNQIALLEARCHEMKPNLGAIAEYKKKEELYLQRVAELDKIT 1114
                                        || | |++ |     +|   |    
0919 -----------------------------------LGEIMEHRFKTYQQFRRCLTLRCKL 0943

1115 YERDSFRQAYEDLRKQRLNEFMAGFYIITNKLKENYQMLTLGGDAELELVDSLDPFSEGI 1174
     |        +++|  ||      |        | |+                 |  +| +
0944 Y--------FDNLLSQRA---YCG--------KMNF-----------------DHKNETL 0967

1175 MFSVRPPKKSWKKIFN----LSGGEKTLSSLALVFALHHYKPTPLYFMDEIDAALDFKNV 1230
       ||+| + + |  ||    |||||++ |++  + +|     +|   +|| |  +|  | 
0968 SISVQPGEGN-KAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNR 1026

1231 SIVAFYIYEQTKN---AQFIIISLRNNMFEISDRLIGIYK 1267
      |    | +   +    |||+++ ++     | +|| | +
1027 RIAMDLILKMADSQRFRQFILLTPQSMSSLPSSKLIRILR 1066