Affine Alignment
 
Alignment between CYP2C8 (top ENST00000371270.6 490aa) and CYP2D6 (bottom ENST00000645361.2 497aa) score 17556

001 MEPFVVL-VLCLSFMLLFSLWRQSCR-RRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFS 058
    +|  | | |+   |+||  |  +  |   + |||| ||| +||+| +| ++    |    
003 LEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLR 062

059 KVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLG------I 112
    + +| ||++     |+|| +|  ||+|||+ +||+ + |   ||+| +  | |       
063 RRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQIL--GFGPRSQGVF 120

113 ISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGC 172
    ++  |  |+| ||||++|||| |+||+|+|  | ||| ||          |  |  +|  
121 LARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDK 180

173 APCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNK 232
    |  ||| |+   +||+| |  || |+    |  +  +    +| |  |+|+   |    |
181 AVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLH-IPALAGK 239

233 VLKNVALTRSYIREKVKEHQASLD-VNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTV 291
    ||+      + + | + ||+ + |    |||  + || +||+ | | +| || |||   |
240 VLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVV 299

292 ADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAV 351
    |||| ||  |||||| +||||++ ||+|  +||+||| |||+ | | | |++||||| ||
300 ADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAV 359

352 VHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGH 411
    +||+||+ |+|| || |  + | + + + ||||||++  |+||| |+  +  |  | | |
360 IHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEH 419

412 FLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTA 471
    |||  |+| | + |+|||||+| | || ||||||||| |++||+|+          +   
420 FLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHG 479

472 VTKGIVSLPPSYQICFIP 489
    |   +|| |  |++| +|
480 VFAFLVS-PSPYELCAVP 496