Alignment between NOTCH4 (top ENST00000375023.3 2003aa) and TIE1 (bottom ENST00000372476.8 1138aa) score 3705

222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----- 276
    |  |+ || |      ||  || +|| |    + |     |+||||| |  ||       
215 CGAGRWGPGC---TKECP--GCLHGGVCH---DHDGE---CVCPPGFTGTRCEQACREGR 263

277 -PDNCVSHQCQNGGTCQDGL-----DTYTCLCPETWTGWDCSEDV------DECETQGPP 324
       +|   ||     |+ ||     | | | |   | |  | |         +|  |   
264 FGQSC-QEQCPGISGCR-GLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQ--C 319

325 HCRNGGTCQNSAGSFHCVCVSGWGGTSCEEN 355
     |+|||||   +|   ||| ||| |  ||++
320 QCQNGGTCDRFSG---CVCPSGWHGVHCEKS 347