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Alignment between SCN4A (top ENST00000435607.3 1836aa) and CACNA1S (bottom ENST00000362061.4 1873aa) score 26334 0110 ALYLLSPFSVVRRGAIKVLIHALFSMFIMITILTNCVFMTMSDPPPWSKN---------V 0160 ||+ |+ + +|+ | ++ | |++|| ||| + + | | | + 0030 ALFCLTLENPLRKACISIVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKL 0089 0161 EYTFTGIYTFESLIKILARGFCVDDFTFLRDPWNWLDFSVIMMAYLTEFVDLGN------ 0214 || | +++ |+ +||+| || +|| || |||+++ + | ++ | 0090 EYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHT 0149 0215 -----------ISALRTFRVLRALKTITVIPGLKTIVGALIQSVKKLSDVMILTVFCLSV 0263 + ||| ||||| |+ ++ +| |+ ++ ++ +++ | + +| +| + + 0150 APMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVII 0209 0264 FALVGLQLFMGNLRQKCVRWPPPFNDTNTTWYSNDTWYGNDTWYGNEMWYGNDSWYANDT 0323 +|++||+|| | + + | + | | 0210 YAIIGLELFKGKMHKTCY------------------FIGTDI------------------ 0233 0324 WNSHASWATNDTFDWDAYISDEGNFYFLEGSNDALLCGNSSDAGHCP-EGYECIKTGRNP 0382 | + +| + | + | | || | 0234 ---------------VATVENE----------EPSPCARTGSGRRCTINGSECRGGWPGP 0268 0383 NYGYTSYDTFSWAFLALFRLMTQDYWENLFQLTLRAAGKTY-MIFFVVIIFLGSFYLINL 0441 |+| | +| | ++ | +++ +| + | ++ | | + |+|| +| ||||+++|| 0269 NHGITHFDNFGFSMLTVYQCITMEGWTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNL 0328 0442 ILAVVAMAYAEQNEATLAEDK-EKEEEFQQMLEKFKKHQEELEKAKAAQALEGGEADGDP 0500 +| |++ + ++ | + +| | ||+ | + + + + + + | 0329 VLGVLSGEFTKEREKAKSRGTFQKLREKQQLDEDLRGYMSWITQGEVMDVEDFRE----- 0383 0501 AHGKDCNGSLDTSQGEKGAPRQSSSGDSGISDAMEELEEAHQKCPPWWYKCAHKVLIWNC 0560 | | +| |+ +| +|++ ++ + | | +++ | | 0384 -------GKLSLDEG--GSDTESLYEIAGLNKIIQFIRHWRQ----W-----NRIFRWKC 0425 0561 CAPWLKFKNIIHLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDNVLTVGNLVFTGI 0620 | || + + + |||| +| ||+ + + | | + 0426 -----------HDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSL 0474 0621 FTAEMVLKLIAMDPYEYFQQGWNIFDSIIV-----TLSLVELGLANVQGLSVLRSFRLLR 0675 || ||++|+ + +|| +| || +| + ||| | |+|||| |||| 0475 FTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLR 0534 0676 VFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKIAL 0735 +||+ | | +|+ |+ + ||+ ++ +| |+| + + |||++|||||| | 0535 IFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYD------FE 0588 0736 DCNLPRWHMHDFFHSFLIVFRILCGE-WIETMWDCM------EVAGQAMCLTVFLMVMVI 0788 | + | + +| + + ||++| || | |++ + | +|+ |+++ | 0589 DTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCI-YFIILFVC 0647 0789 GNLVVLNLFLALLLSSFSADSLAASDEDGEMNNLQIAIGRIKLGIGFAKAFLLGLLHGKI 0848 || ++||+|||+ + |+|| ++ | | 0648 GNYILLNVFLAI-----AVDNLAEAES------------------------LTSAQKAKA 0678 0849 LSPKDIMLSLGEADGAGEAGEAGETAPEDEKKEPPEEDLKKDNHILNHMGLADGPPSSLE 0908 | +| | | + | | | + |+| | | |++ + 0679 EEKKRRKMSKGLPDKSEE--EKSTMAKKLEQKPKGE-----------------GIPTTAK 0719 0909 L------DHLNFINNPYLTIQVPIASEESDLEMPTEEETDTFSEPEDSKKPPQPLYDGNS 0962 | ++| + +|| + | || + |+| |+|| 0720 LKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPR-------------PRPL----- 0761 0963 SVCSTADYKPPEEDPEEQAEENPEGEQPEECFTEACVQRWPCLYVDISQGRGKKWWTLRR 1022 | +|+| || ++ + +| 0762 ----------AELQLKEKAVPIPEASS---------------FFIFSPTNK------IRV 0790 1023 ACFKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFIMEMLL 1082 | +|| || ||+ ||||| ||| || | + ||++ | || +| +|++| 0791 LCHRIVNATWFTNFILLFILLSSAALAAED-PIRADSMRNQILKHFDIGFTSVFTVEIVL 0849 1083 KWVAYGFKV----YFTNAWCWLDFLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLR 1138 | || + + | + || |+| ||+||+ | | + +| || || ||||| 0850 KMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISM---GLESSAISVVKILRVLRVLRPLR 0906 1139 ALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYC--INTTTSE 1196 |++| +|++ || + || +| |++|| + +|+ +|| || |||+ | ++ | | 0907 AINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEE 0966 1197 R----FDISEVNNKSECESLMHTGQVRWLNVKVNYDNVGLGYLSLLQVATFKGWMDIMYA 1252 + + + + + | | | |++ ++||| +|| |+||+|| ++| 0967 ECRGYYYVYKDGDPMQIE-LRHR---EWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLYK 1022 1253 AVDSREKEEQPQYEVNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGKDIFM 1312 |+|| ++ | | + | ++|+|+|| +|| +|+|+| +| | +| |+ + 1023 AIDSNAEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQ-----GETEYK 1077 1313 TEEQKKYYNAMKKLGSKKPQKPIPRPQNKIQGMVYDLVTKQAFDITIMILICLNMVTMMV 1372 | | + | |+| | |+ +|| |+ + || || + + + 1078 NCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGM 1137 1373 ETDNQSQLKVDILYNINMIFIIIFTGECVLKMLALR-QYYFTVGWNIFDFVVVILSIVGL 1431 + |||+ | +|+ | |||| | +||++| + + || ||+|||++|| ||+ + 1138 QHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDV 1197 1432 ALSDLIQKYFVSPTLF-------------------RVIRLARIGRVLRLIRGAKGIRTLL 1472 ||++ | |+ || |+ |+++|+ |+|+|||| 1198 ILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLL 1257 1473 FALMMSLPALFNIGLLLFLVMFIYSIFGMSNFAYVKKESG--IDDMFNFETFGNSIICLF 1530 + + | || + ||+ ++ |||++ || | + | |+ ||+|| +++ || 1258 WTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLF 1317 1531 EITTSAGWDGLLNPILNSGPPDCDPNLE-NPGTSVKGDCGNPSIGICFFCSYIIISFLIV 1589 | | +| + | ||| + || || + +| |+ ++ +| 1318 RCATGEAWQEIL--LACSYGKLCDPESDYAPGEEY--TCGT-NFAYYYFISFYMLCAFLV 1372 1590 VNMYIAIILENFNVATEESSEPLGEDDFEMFYETWEKFDPDATQFIAYSRLSDFVDTLQE 1649 +|+++|+|++||+ | + | || + | | ++||+| | + + + +| 1373 INLFVAVIMDNFDYLTRDWS-ILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQP 1431 1650 PLRIAK--PNKI---KLITLDLPMVPGDKIHCLDILFALTKEVLGDSGEMDALKQTMEEK 1704 || | |+++ +|+ +++|+ + |||| + ||| | 1432 PLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVR---------TALKIKTEGN 1482 1705 FMAAN 1709 | || 1483 FEQAN 1487