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Alignment between SCN7A (top ENST00000643258.1 1682aa) and CACNA1C (bottom ENST00000399655.6 2138aa) score 20786 0096 SILCTLSPFNCIRRTTIKVLVHPFFQLFILISVLIDCVFMSL-------------TNLPK 0142 ++|| |+ | ||| | ++ |++ ||+++ +|| +++ +|| + 0103 ALLC-LTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLER 0161 0143 WRPVLENTLLGIYTFEILVKLFARGVWAGSFSFLGDPWNWLDFSVTV---FEVIIRYSP- 0198 +| | |+| | +|+ | |+ ++| + || ||| + | | |+ + 0162 ----VEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK 0217 0199 -----------LDF-IPTLQTARTLRILKIIPLNQGLKSLVGVLIHCLKQLIGVIILTLF 0246 | + |+ | || |+++ |+ ++ +| + |+ + +| || 0218 ADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLF 0277 0247 FLSIFSLIGMGLFMGNLKHKCFRWPQENENETLHNRTGNPYYIRETENFYYLEGERYALL 0306 + |+++||+ |||| + |+ || + +| 0278 VIIIYAIIGLELFMGKMHKTCYN--QEGIADVPAEDDPSP-------------------- 0315 0307 CGNRTDAG-QCPEGYVCVKAGINPDQGFTNFDSFGWALFALFRLMAQD-YPEVLYHQILY 0364 | | | || | || | | ||||+| +|+ +|+ + + + +||| + 0316 CALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLY-WVND 0374 0365 ASGKVY-MIFFVVVSFLFSFYMASLFLGILAMAYEEEKQRV---GEISKKIEPKFQQTGK 0420 | |+ + |+|| + + ||++ +| ||+|+ + +|+++ |+ | | || + 0375 AVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREK--QQLEE 0432 0421 ELQ------------------EGNETDEAKTIQIEMKKRSPISTDTSL--DVL-EDATLR 0459 +|+ || + ++ + + + + ++|+ |+ |+ | 0433 DLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGAR 0492 0460 HKEELEKSKKICPLYWYKFAKTFLIWNCSPCWLKLKEFVHRIIMAPFTDLFLIICIILNV 0519 + || ||++ + || | | + | + +| + || 0493 LAHRISKS---------KFSRYWRRWN-RFCRRKCRAAVKSNVFY----WLVIFLVFLNT 0538 0520 CFLTLEHYPMSKQTNTLLNIGNLVFIGIFTAEMIFKIIAMHPYGYFQVGWNIFDSMIVFH 0579 + ||| + + | + +|||||+ |+ ++ || +| || +| 0539 LTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCG 0598 0580 GLIELCLANV-----AGMALLRLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLL 0634 |++| | |+++|| |+|||||+ +|| + |+ || || ++ |+||| 0599 GILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLL 0658 0635 FTFIFFSAAFGMKLFGK--NYEEFVCHIDKDCQLPRWHMHDFFHSFLNVFRILCGE-WVE 0691 | || + ||+||| |++| | | +| | | ||+|| || | 0659 FLFIIIFSLLGMQLFGGKFNFDEM--------QTRRSTFDNFPQSLLTVFQILTGEDWNS 0710 0692 TLWD-CMEVAGQSW-----CIPFYLMVILIGNLLVLYLFLAL-VSSFSSCKDVTAEENNE 0744 ++| | | |+ || +++++ + || ++| +|||+ | + + + +|+ + | 0711 VMYDGIMAYGGPSFPGMLVCI-YFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEE 0769 0745 AKNLQLAVARIKKGINYVLLKILCKTQNVPKDTMDHVNEVYVKEDISDHTLSELSNTQDF 0804 + + | | +| + |+ + | + | | + | + 0770 EEEKE--------------RKKLARTAS-PEKKQELVEKPAVGE-----SKEEKIELKSI 0809 0805 LKDKEKSSGTEKNATE---NESQSLIPSPSVSETVPIASGESDIENLDNKEIQSKSGDGG 0861 | | |+ | + ||++ | |+ | +|| | | | + | 0810 TADGESPPATKINMDDLQPNENEDKSPYPN-----PETTGEEDEE-----EPEMPVG--- 0856 0862 SKEKIKQSSSSECSTVDIAISEEEEMFYGGERSKHLKNGCRRGSSLGQISGASKKGKIWQ 0921 + + | + + | | ++ 0857 --PRPRPLSELHLKEKAVPMPEASAFFIFSSNNR-------------------------- 0888 0922 NIRKTCCKIVENNWFKCFIGLVTLLSTGTLAFEDIYMDQRKTIKILLEYADMIFTYIFIL 0981 | | +|| + | | |||+ +|| || || | |++|| || + 0889 -FRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILF-YFDIVFTTIFTI 0946 0982 EMLLKWMAYG---FKAYFSNGWYR-LDFVVVIVFCLS--LIGKTREELKPLISMKFLRPL 1035 |+ || ||| | | ++ || +|| | +| + +| | ++ |||| 0947 EIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPL 1006 1036 RVLSQFERMKVVVRALIKTTLPTLNVFLVCLMIWLIFSIMGVDLFAGRFYECIDPTSGER 1095 | +++ + +| ||+ + |+ +| ++ +|+ +|| || |+ | | | 1007 RAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD------ 1060 1096 FPSSEVMNKSRCES--LLFNESML---------WENAKMNFDNVGNGFLSLLQVATFNGW 1144 | ++ |+ + + + + |||+| +|||| ++| |+|| || 1061 ---SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGW 1117 1145 ITIMNSAIDSVAVNIQPHFEVNIYMYCYFINFIIFGVFLPLSMLITVIIDNFNKHKIKLG 1204 ++ +||| + | + + + +|| +|| | +++ + +| | + 1118 PELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQ----- 1172 1205 GSNIFITVKQRKQYRRLKKLMYEDSQRPVPR--PLNKLQGFIFDVVTSQAFNVIVMVLIC 1262 | + + | |+ + | ||+ | | |+ | ++ || | | ++ ||| 1173 GEQEYKNCELDKNQRQC--VEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLIL 1230 1263 FQAIAMMIDTDVQSLQMSIALYWINSIFVMLYTMECILKLIAFR-CFYFTIAWNIFDFMV 1321 | + + || ||+ +| +| |+|+| |||||||+ || ||| || ++ 1231 LNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALI 1290 1322 VIFSITGL------------CLPM--TVGSYLVPPSLVQLILLSRIIHMLRLGKGPKVFH 1367 |+ || + | | + + + +| + |++ +| |+| 1291 VVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEG---IR 1347 1368 NLMLPLMLSLPALLNIILLIFLVMFIYAVFGMYNFAYV--KKEAGINDVSNFETFGNSML 1425 |+ + | || + ||| ++ ||||| || | + || +||+|| ++| 1348 TLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVL 1407 1426 CLFQVAIFAGWDGMLDAIFNSKWSDCDPDKINPGTQVRGD--CGNPSVGIFYFVSYILIS 1483 ||+ | | ++ | | | |+ | |+ ||+ | +|||+|+ ++ 1408 LLFRCATGEAWQDIMLACMPGK--KCAPES-EPSNSTEGETPCGS-SFAVFYFISFYMLC 1463 1484 WLIIVNMYIVVVMEFLNIASKKKNKTLSEDDFRKFFQVWKRFDPDRTQYIDSSKLSDFAA 1543 +|+|+++ |+|+ + ++ + | +| ++| +||+ | + 1464 AFLIINLFVAVIMDNFDYLTRDWS-ILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLR 1522 1544 ALDPPLFMAK--PNK---GQLIALDLPM 1566 + ||| | |++ +|+++++|+ 1523 RIQPPLGFGKLCPHRVACKRLVSMNMPL 1550