Alignment between CYP3A4 (top ENST00000651514.1 503aa) and CYP2D6 (bottom ENST00000645361.2 497aa) score 5168

002 ALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILS---YHKGFC 058
    ||+|       | + |++ || +   |    +     ||| ||| |||+|     +  +|
005 ALVP-------LAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYC 057

059 MFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPV------G 112
     || +  +++| |+       ||+ +     ++  ||   +   |  ||  |+      |
058 -FD-QLRRRFGDVFSLQLAWTPVVVLNGLAAVREALV--THGEDTADRPPVPITQILGFG 113

113 FMKSAISIAE-DEEWKRLRSLLSPTFTS---GKLKEMVPIIAQYGDVLVRNLRREAETGK 168
         + +|     |+  |     |  +   || | +   + +    |         +|+
114 PRSQGVFLARYGPAWREQRRFSVSTLRNLGLGK-KSLEQWVTEEAACLCAAFAN--HSGR 170

169 PVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFP- 227
    |     +      +|| | + |                     ||++ || || +     
171 PFRPNGLLDKAVSNVIASLTCG--------------------RRFEYDDPRFLRLLDLAQ 210

228 --------FLIPILE----VLNICVFPREVTNFLRKSVKRMKESRLE-----DTQKHRVD 270
            ||  +|     +|+|     +|  | +  + ++ |   |     |  +   |
211 EGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRD 270

271 FLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQK 330
      +  +      +     + +|  |         ||  |||+ |++ +  +  |||||++
271 LTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRR 330

331 LQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA-MRLERVCKKDVEINGMFIP 389
    +|+||| |+     |       | |   |++|  |   |  + +  +  +|+|+ |  ||
331 VQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIP 390

390 KGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFAL 449
    ||  ++    ++ +|   | +| +| || |       + |  + || +| | |+|   | 
391 KGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLAR 450

450 MNMKLALIRVLQNFSF 465
    | + |    +||+|||
451 MELFLFFTSLLQHFSF 466