UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F20D6.11	F20D6.11	0	chrV 8,197,919	F20D6.11 encodes a putative flavin-adenine dinucleotide (FAD)-binding oxidoreductase orthologous to human AIFM3 (AIFL), and paralogous to WAH-1 and mammalian PDCD8 (AIF; OMIM:300169, mutated in Harlequin mice); F20D6.11 is expressed in pharynx, anal depressor and body wall muscles, the reproductive system (including spermatheca), and unidentified tail cells; given its orthology to AIFM3, F20D6.11 may promote apoptosis; however, F20D6.11 has no obvious function in mass RNAi assays.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C44B9.1	C44B9.1	n/a	chrIII 10,871,842	contains similarity to Interpro domains IPR008162 (Inorganic pyrophosphatase), IPR001220 (Legume lectin, beta domain)
4	F16F9.4	F16F9.4	n/a	chrX 8,461,517	contains similarity to Pfam domain PF07859 alpha/beta hydrolase fold contains similarity to Interpro domains IPR002168 (Lipase, GDXG, active site), IPR017157 (Arylacetamide deacetylase), IPR013094 (Alpha/beta hydrolase fold-3)
5	nas-36	C26C6.3	n/a	chrI 7,529,499	nas-36 encodes an astacin-like protease; nas-36 activity is required for molting; a nas-36::gfp reporter is expressed in hypodermal cells.
6	ZK185.2	ZK185.2	n/a	chrIV 4,539,155	ZK185.2 encodes an ortholog of human SLC41A1 (OMIM:610801) and bacterial MgtE; like its orthologs, ZK185.2 is predicted to transport Mg(2+) into cells; ZK185.2 is paralogous to K07H8.2 and ZK1053.6, and has no obvious function in mass RNAi assays.
7	ubc-20	F40G9.3	n/a	chrIII 189,890	C. elegans UBC-20 protein; contains similarity to Pfam domain PF00179 Ubiquitin-conjugating enzyme contains similarity to Interpro domains IPR000608 (Ubiquitin-conjugating enzyme, E2), IPR009060 (UBA-like), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)
8	M04F3.2	M04F3.2	n/a	chrI 4,766,635	contains similarity to Bradyrhizobium japonicum 30S ribosomal protein S6.; SW:Q89MW3
9	tap-1	C44H4.5	n/a	chrX 14,590,650	C. elegans TAP-1 protein; contains similarity to Pfam domain PF00481 Protein phosphatase 2C contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR014045 (Protein phosphatase 2C, N-terminal), IPR015655 (Protein phosphatase 2C)
10	C50D2.8	C50D2.8	n/a	chrII 97,034	contains similarity to Pfam domain PF03194 LUC7 N_terminus contains similarity to Interpro domain IPR004882 (LUC7 related)
11	fbxa-84	T09F5.11	n/a	chrV 15,183,260	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
12	F58G11.2	F58G11.2	n/a	chrV 13,667,324	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR002952 (Eggshell protein), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
13	F38A1.8	F38A1.8	n/a	chrIV 1,236,362	contains similarity to Pfam domains PF00448 (SRP54-type protein, GTPase domain) , PF02881 (SRP54-type protein, helical bundle domain) , PF04086 (Signal recognition particle, alpha subunit, N-terminal) contains similarity to Interpro domains IPR007222 (Signal recognition particle receptor, alpha subunit, N-terminal), IPR000897 (Signal recognition particle, SRP54 subunit, GTPase), IPR011012 (Longin-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR003593 (AAA+ ATPase, core)
14	dpy-1	M01E10.2	n/a	chrIII 2,041,006	dpy-1 encodes a collagen that affects body length and alae formation; site of action localized to the hyp7 syncytium, based on mosaic analysis.
15	lin-12	R107.8	n/a	chrIII 9,065,726	The lin-12 gene encodes a member of the Notch/LIN-12/glp-1 transmembrane receptor family that affects cell fate specification events during development, notably including the anchor cell, secondary vulval precursor cells, and the embryonic ABplp lineage; its expression is dynamic, including Z1.ppp and Z4.aaa, ABplaa descendants, ABplpa descendants, and the intestinal primordium.
16	F39H12.1	F39H12.1	n/a	chrX 836,268	contains similarity to Homo sapiens nuclear pore complex-associated protein TPR; ENSEMBL:ENSP00000356448
17	try-10	F15B9.5	n/a	chrV 13,011,526	C. elegans TRY-10 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine)
18	figl-1	F32D1.1	n/a	chrV 4,343,730	F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays.
19	VT23B5.2	VT23B5.2	n/a	chrIV 12,671,338	VT23B5.2 encodes a BEACH-WD40 domain-containing protein that is orthologous to human WDFY3 (WD repeat and FYVE domain containing 3); loss of VT23B5.2 activity via mutation or large-scale RNAi screens in a wild-type background results in no obvious abnormalities.
20	T20D4.4	T20D4.4	n/a	chrV 3,416,870	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
21	T19C3.4	T19C3.4	n/a	chrIII 619,226	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
22	F53F1.3	F53F1.3	n/a	chrV 13,409,019	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
23	Y54E5A.6	Y54E5A.6	n/a	chrI 14,709,596	contains similarity to Pfam domains PF01207 (Dihydrouridine synthase (Dus)) , PF00035 (Double-stranded RNA binding motif) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like), IPR000632 (Yeast Mrs6p protein), IPR001269 (Dihydrouridine synthase, DuS)
24	ctg-1	H06O01.3	n/a	chrI 7,007,341	C. elegans CTG-1 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
25	F13E6.5	F13E6.5	n/a	chrX 10,696,500	contains similarity to Pfam domain PF01569 PAP2 superfamily contains similarity to Interpro domains IPR000326 (Phosphatidic acid phosphatase type 2/haloperoxidase), IPR016118 (Phosphatidic acid phosphatase/chloroperoxidase, N-terminal)
26	tag-51	K02F3.1	n/a	chrIII 855,363	C. elegans TAG-51 protein ;
27	C03B1.7	C03B1.7	n/a	chrX 6,343,858	contains similarity to Sulfolobus tokodaii DNA double-strand break repair rad50 ATPase.; SW:Q96YR5
28	T07F10.5	T07F10.5	n/a	chrV 12,866,209	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR002168 (Lipase, GDXG, active site), IPR002018 (Carboxylesterase, type B)
29	Y39A1A.6	Y39A1A.6	n/a	chrIII 10,616,526	contains similarity to Interpro domains IPR005727 (Ribosomal protein L22, bacterial-type), IPR001063 (Ribosomal protein L22/L17)
30	C42C1.7	C42C1.7	n/a	chrIV 12,297,231	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
31	math-19	C40D2.1	n/a	chrII 1,999,260	C. elegans MATH-19 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
32	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
33	K09C4.5	K09C4.5	n/a	chrX 3,284,155	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
34	F32A11.1	F32A11.1	n/a	chrII 13,158,777	contains similarity to Interpro domains IPR016071 (Staphylococcal nuclease (SNase-like), OB-fold), IPR006021 (Staphylococcal nuclease (SNase-like))
35	dnc-1	ZK593.5	n/a	chrIV 10,929,896	DNC-1 encodes a dynactin, orthologous to Drosophila GLUED, that is required for pronuclear migration and centrosome separation in one-cell embryos and for the correct alignment of mitotic spindles in early embryos; DNC-1 shares embryonic functions with DNC-2, DHC-1, LIS-1 and NUD-1; DNC-1 is located at cortical microtubule attachment sites.
36	srt-69	B0238.8	n/a	chrV 5,264,800	C. elegans SRT-69 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
37	C06E1.3	C06E1.3	n/a	chrIII 8,582,414	contains similarity to Drosophila melanogaster Flybase gene name is mol-PD;; FLYBASE:CG4482
38	F22G12.3	F22G12.3	n/a	chrI 13,153,129	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
39	aps-1	F29G9.3	n/a	chrV 6,018,404	aps-1 encodes an adaptin: specifically, it encodes an ortholog of the sigma1 subunit of adaptor protein complex 1 (AP-1).
40	F08G12.1	F08G12.1	n/a	chrX 11,303,901	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
41	T04F8.6	T04F8.6	n/a	chrX 11,669,654	contains similarity to Interpro domain IPR011992 (EF-Hand type)
42	R09D1.7	R09D1.7	n/a	chrII 9,455,937	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR001574 (Ribosome-inactivating protein)
43	C04G6.2	C04G6.2	n/a	chrII 5,093,709	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
44	clh-6	R07B7.1	n/a	chrV 12,061,778	clh-6 encodes a voltage-gated chloride channel orthologous to the human CLCN7 chloride channel (OMIM:602727, which when mutated lead to osteopetrosis); although the precise role of CLH-6 in C. elegans development and/or behavior is not yet known, CLH-6 expression is detected in two GABA-ergic neurons, RMEL and RMER, suggesting that CLH-6 could play a role in membrane excitability and/or GABA packaging; as CLH-6 is also detected in many non-neuronal tissues, such as the gut and body wall muscle, it could also have a broader role in such as processes as transepithelial transport and muscle excitation.
45	C18B12.6	C18B12.6	n/a	chrX 15,005,608	contains similarity to Pfam domain PF07970 Protein of unknown function (DUF1692) contains similarity to Interpro domain IPR012936 (Protein of unknown function DUF1692)
46	F34H10.2	F34H10.2	n/a	chrX 9,630,584	contains similarity to Anabaena sp Hypothetical protein Alr0331.; TR:Q8YZX4
47	T01C3.2	T01C3.2	n/a	chrV 14,991,380	T01C3.2 encodes a divergent ortholog of Drosophila melanogaster E(Y)2 and budding yeast Sus1p; by orthology, T01C3.2 is predicted to enable both transcriptional activation and silencing in chromatin; however, T01C3.2 has no obvious function in mass RNAi assays.
48	sre-12	T07H8.7	n/a	chrV 6,978,417	C. elegans SRE-12 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR001680 (WD40 repeat)
49	F22E5.11	F22E5.11	n/a	chrII 2,644,695	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
50	C06H5.6	C06H5.6	n/a	chrV 17,884,381	contains similarity to Pfam domains PF00083 (Sugar (and other) transporter) , PF07690 (Major Facilitator Superfamily) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)