UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	dyb-1	F47G6.1	0	chrI 1,486,779	The dyb-1 gene encodes a homolog of mammalian alpha-dystrobrevin (DTNA; OMIM:601239), mutation of which can lead to left ventricular noncompaction with congenital heart defects.
2	F02D10.4	F02D10.4	n/a	chrX 13,458,404	contains similarity to Emericella nidulans Anucleate primary sterigmata protein B.; SW:APSB_EMENI
3	C44B12.3	C44B12.3	n/a	chrIV 1,105,091
4	rpm-1	C01B7.6	n/a	chrV 8,812,661	rpm-1 encodes an E3 ubiquitin ligase that contains an N-terminal RCC1 (regulator of chromosome condensation)-like guanine nucleotide exchange factor (GEF) domain and that is orthologous to Drosophila highwire and murine Phr1; RPM-1 functions autonomously within several different types of neurons to regulate presynaptic differentiation; in regulating axon termination, RPM-1 acts through the GLO-4 guanine nucleotide exchange factor that positively regulates vesicular trafficking through GLO-1/Rab; in regulating synaptogenesis, RPM-1 functions as part of an SCF-like ubiquitin ligase complex that negatively regulates signaling through the DLK-1 MAP kinase cascade; RPM-1 is expressed in most, if not all, neurons from the comma stage of embryogenesis through adulthood; RPM-1 expression is also seen in the pharynx, coelomocytes, and distal tip cells; in neurons, RPM-1 localizes to presynaptic terminals.
5	C41G7.7	C41G7.7	n/a	chrI 9,534,916	contains similarity to Plasmodium falciparum S-antigen (Fragment).; TR:Q9GZB4
6	H01G02.2	H01G02.2	n/a	chrIV 11,799,864	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
7	C28H8.7	C28H8.7	n/a	chrIII 5,886,352	contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
8	Y116A8C.23	Y116A8C.23	n/a	chrIV 17,054,490	contains similarity to Interpro domain IPR000694 (Proline-rich region)
9	T28D9.11	T28D9.11	n/a	chrII 6,491,500
10	fbxb-107	F29A7.2	n/a	chrII 2,760,240	C. elegans FBXB-107 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
11	F39G3.3	F39G3.3	n/a	chrV 4,732,719	contains similarity to Homo sapiens Isoform 2 of Zinc finger CCCH domain-containing protein 13; ENSEMBL:ENSP00000282007
12	hum-7	F56A6.2	n/a	chrI 596,704	hum-7 encodes a class IX unconventional myosin heavy chain that contains a myosin motor domain in the head region and zinc-finger and rhoGAP (rho GTPase activating protein) domains in the tail region; HUM-7 is required during embryogenesis for cytokinesis and normal cytoplasmic rearrangements, and by homology, may function in organization of the actin cytoskeleton; the precise expression and localization patterns of HUM-7 are not yet known.
13	srz-60	C04C3.1	n/a	chrIV 3,429,627	C. elegans SRZ-60 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
14	jph-1	T22C1.7	n/a	chrI 7,948,882	jph-1 encodes a junctophilin, a protein that belongs to a transmembrane family of proteins implicated in the formation of the junctional membrane complex that forms between the plasma membrane and the endoplasmic reticulum in excitable cells; this complex facilitates cross-talk between the cell surface and intracellular ionic channels; RNA interference of jph-1 results in a locomotion defect suggesting impaired body-wall muscle function; a jph-1 promoter-gfp fusion reporter is expressed in all muscle cells and certain neurons of the nerve ring.
15	T03D8.2	T03D8.2	n/a	chrV 20,833,812	contains similarity to Pfam domain PF00164 Ribosomal protein S12 contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR006032 (Ribosomal protein S12/S23), IPR012340 (Nucleic acid-binding, OB-fold), IPR005679 (Ribosomal protein S12, bacterial-type)
16	lgc-34	T27A1.4	n/a	chrII 528,462	C. elegans LGC-34 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
17	C06A5.10	C06A5.10	n/a	chrI 5,982,746
18	Y45F10A.3	Y45F10A.3	n/a	chrIV 13,511,278	contains similarity to Mus musculus Probable arylformamidase (EC 3.5.1.9) (Kynurenine formamidase) (KF).; SW:Q8K4H1
19	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
20	T12E12.6	T12E12.6	n/a	chrIV 5,570,564	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
21	K09D9.3	K09D9.3	n/a	chrV 4,020,029
22	F21D9.4	F21D9.4	n/a	chrV 19,255,280	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
23	C49F8.2	C49F8.2	n/a	chrX 13,374,194	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
24	F16C3.2	F16C3.2	n/a	chrI 10,152,680	contains similarity to Clostridium acetobutylicum DNA repair protein recN, ATPase.; TR:Q97HD9
25	lrk-1	T27C10.6	n/a	chrI 10,886,998	lrk-1 encodes a homolog of GbpC, the primary high-affinity cGMP-binding protein in Dictyostelium discoideum, which is required for normal phosphorylation and cytoskeletal assembly of myosin during chemotaxis; GbpC is generally conserved in eukaryotes, with homologs in mammals and flies.
26	K09E4.2	K09E4.2	n/a	chrII 14,130,163	contains similarity to Pfam domain PF05208 ALG3 protein contains similarity to Interpro domains IPR007873 (ALG3), IPR013838 (Beta tubulin, autoregulation binding site)
27	C35B1.2	C35B1.2	n/a	chrIV 4,094,546	n/a
28	gsk-3	Y18D10A.5	n/a	chrI 12,821,999	C. elegans GSK-3 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
29	nas-14	F09E8.6	n/a	chrIV 13,172,108	nas-14 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-14::GFP promoter fusion is expressed in the pharynx.
30	adm-2	C04A11.4	n/a	chrX 13,691,794	adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family); like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development.
31	C56G2.3	C56G2.3	n/a	chrIII 6,347,461	contains similarity to Pfam domain PF01746 tRNA (Guanine-1)-methyltransferase contains similarity to Interpro domains IPR016009 (tRNA (guanine-N1-)-methyltransferase), IPR007356 (tRNA (guanine-N1-)-methyltransferase, eukaryotic)
32	clec-191	F38C2.6	n/a	chrIV 16,280,134	C. elegans CLEC-191 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	sea-2	K10G6.3	n/a	chrII 3,966,905	sea-2 is an autosomal signal element gene, whose protein product contains four C2H2 zinc finger domains and three involucrin repeats embedded in extensive regions of low-complexity (e.g., glutamine/asparagine-rich) protein sequence; sea-2 has no obvious biological function in mass RNAi assays.
34	T23G5.6	T23G5.6	n/a	chrIII 9,241,340	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domain IPR000637 (HMG-I and HMG-Y, DNA-binding)
35	F54H12.5	F54H12.5	n/a	chrIII 7,971,111	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
36	lam-1	W03F8.5	n/a	chrIV 5,176,291	lam-1 encodes a laminin beta that affects degenerin-induced cell death and is required redundantly with lam-2 for morphogenesis.
37	nxf-1	C15H11.3	n/a	chrV 14,414,076	nxf-1 encodes a homolog of human TAP protein, a member of the NXF family of shuttling transport receptors for nuclear export of mRNA; binds RNA directly and its function has been shown to be conserved with the NXF family.
38	fox-1	T07D1.4	n/a	chrX 2,448,279	fox-1 encodes an RNA-binding protein of the RNA recognition motif (RRM) superfamily of ribonucleic acid binding proteins; during C. elegans development, FOX-1 functions redundantly with other numerator elements to effect proper dosage compensation in the early embryo; in influencing dosage compensation, FOX-1 likely acts via post-transcriptional regulation of xol-1 mRNA levels; in addition to its role in dosage compensation, fox-1 activity is also required for normal male mating behavior; Western analysis and lacZ reporter constructs indicate that FOX-1 is expressed throughout the life cycle, beginning at the 18-20-cell stage of embryogenesis and continuing on through larval stages and into adult hermaphrodites and males; while early embryonic expression of fox-1 is ubiquitous, postembryonic expression is limited to a subset of head and tail neurons.
39	M151.1	M151.1	n/a	chrII 3,642,785
40	F13E6.4	F13E6.4	n/a	chrX 10,693,437	contains similarity to Pfam domain PF00397 WW domain contains similarity to Interpro domains IPR002349 (WW), IPR001202 (WW/Rsp5/WWP)
41	cyp-33D1	K05D4.4	n/a	chrV 16,174,796	C. elegans CYP-33D1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR008071 (Cytochrome P450, E-class, group I, CYP2J-like), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
42	K08B12.3	K08B12.3	n/a	chrV 6,236,378	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006355 (HAD-superfamily hydrolase, subfamily IIA, hypothetical 2), IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR005834 (Haloacid dehalogenase-like hydrolase)
43	dsl-2	W09G12.1	n/a	chrIV 1,203,808	dsl-2 encodes a putative transmembrane protein whose extracellular domain has single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-2 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
44	set-6	C49F5.2	n/a	chrX 11,972,276	set-6 encodes a putative histone H3 lysine-9 methyltransferase; SET-6 has no non-nematode orthologs, but several paralogs (SET-13, SET-15, SET-19, SET-20, SET-21, and SET-32); neither set-6(tm1611) nor set-6(RNAi) have any obvious phenotypes.
45	R03H10.7	R03H10.7	n/a	chrII 4,177,232	contains similarity to Pfam domain PF01336 OB-fold nucleic acid binding domain contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR004365 (Nucleic acid binding, OB-fold, tRNA/helicase-type)
46	tag-278	C02F12.7	n/a	chrX 3,686,384	C. elegans TAG-278 protein; contains similarity to Interpro domain IPR000533 (Tropomyosin)
47	K03H6.1	K03H6.1	n/a	chrIV 1,525,035	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
48	srbc-34	Y113G7B.9	n/a	chrV 20,202,676	C. elegans SRBC-34 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	C26E6.12	C26E6.12	n/a	chrIII 4,931,357	contains similarity to Pfam domains PF01018 (GTP1/OBG) , PF01926 (GTPase of unknown function) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR014100 (GTP-binding protein Obg/CgtA), IPR006169 (GTP1/OBG subdomain), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG)
50	cdd-1	C47D2.2	n/a	chrX 8,209,904	cdd-1 encodes a cytidine deaminase that contains a zinc-binding region; expressed in the intestine.