UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	YAL065C	YAL065C	463	n/a	chrI 11,758	Putative protein of unknown function has homology to FLO1 possible pseudogene
2	ARG82	YDR173C	463	n/a	chrIV 811,098	Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5 also has diphosphoinositol polyphosphate synthase activity regulates arginine-, phosphate-, and nitrogen-responsive genes
3	PAU22	YPL282C	463	n/a	chrXVI 8,180	Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions identical to Pau21p encodes 2 proteins that are translated from 2 different start codons
4	PAU14	YIL176C	463	n/a	chrIX 8,974	Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions identical to Pau1p
5	UTR1	YJR049C	463	n/a	chrX 527,680	ATP-NADH kinase phosphorylates both NAD and NADH active as a hexamer enhances the activity of ferric reductase (Fre1p)
6	LRE1	YCL051W	463	n/a	chrIII 36,740	Protein involved in control of cell wall structure and stress response overproduction confers resistance to cell-wall degrading enzymes exhibits genetic interactions with genes involved in the cell wall integrity pathway
7	YJU2	YKL095W	463	n/a	chrXI 262,695	Essential protein required for pre-mRNA splicing associates transiently with the spliceosomal NTC ("nineteen complex") and acts after Prp2p to promote the first catalytic reaction of splicing
8	RAD14	YMR201C	463	n/a	chrXIII 666,444	Protein that recognizes and binds damaged DNA during nucleotide excision repair subunit of Nucleotide Excision Repair Factor 1 (NEF1) contains zinc finger motif homolog of human XPA protein
9	PSO2	YMR137C	463	n/a	chrXIII 543,970	Nuclease required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives induced by UV-irradiation
10	MET4	YNL103W	463	n/a	chrXIV 428,744	Leucine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pathway, requires different combinations of the auxiliary factors Cbf1p, Met28p, Met31p and Met32p
11	SPR1	YOR190W	463	n/a	chrXV 691,363	Sporulation-specific exo-1,3-beta-glucanase contributes to ascospore thermoresistance
12	FZF1	YGL254W	463	n/a	chrVII 22,753	Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers
13	BCK2	YER167W	463	n/a	chrV 519,493	Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity overproduction suppresses pkc1 mutations
14	RIM101	YHL027W	463	n/a	chrVIII 52,049	Transcriptional repressor involved in response to pH and in cell wall construction required for alkaline pH-stimulated haploid invasive growth and sporulation activated by proteolytic processing similar to A. nidulans PacC
15	PAU16	YKL224C	463	n/a	chrXI 1,995	Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions
16	YKL222C	YKL222C	463	n/a	chrXI 4,561	Protein of unknown function that may interact with ribosomes, based on co-purification experiments similar to transcriptional regulators from the zinc cluster (binuclear cluster) family null mutant is sensitive to caffeine
17	AVT3	YKL146W	463	n/a	chrXI 172,822	Vacuolar transporter, exports large neutral amino acids from the vacuole member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
18	BYE1	YKL005C	463	0	chrXI 433,985	Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit
19	YKR015C	YKR015C	463	n/a	chrXI 467,814	Putative protein of unknown function
20	YBR063C	YBR063C	463	n/a	chrII 367,577	Putative protein of unknown function YBR063C is not an essential gene
21	PAU24	YBR301W	463	n/a	chrII 809,238	Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p member of the seripauperin multigene family encoded mainly in subtelomeric regions expressed under anaerobic conditions, completely repressed during aerobic growth
22	BIT2	YBR270C	463	n/a	chrII 743,579	Subunit of TORC2, a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates similar to Bit61p
23	SIC1	YLR079W	463	n/a	chrXII 287,247	Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover functional homolog of mammalian Kip1
24	YHL008C	YHL008C	463	n/a	chrVIII 93,568	Putative protein of unknown function, may be involved in the uptake of chloride ions does not appear to be involved in monocarboxylic acid transport green fluorescent protein (GFP)-fusion protein localizes to the vacuole
25	FLO5	YHR211W	463	n/a	chrVIII 527,005	Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile similar to Flo1p
26	YHR213W	YHR213W	463	n/a	chrVIII 539,449	Possible pseudogene has similarity to Flo1p, which is a lectin-like protein involved in flocculation
27	RAD55	YDR076W	463	n/a	chrIV 599,078	Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis forms heterodimer with Rad57p
28	SNF11	YDR073W	463	n/a	chrIV 592,693	Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation interacts with a highly conserved 40-residue sequence of Snf2p
29	SHU2	YDR078C	463	n/a	chrIV 602,533	Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation associates with Shu1p, Psy3p, and Csm2p
30	MET30	YIL046W	463	n/a	chrIX 269,612	F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex interacts with and regulates Met4p, localizes within the nucleus
31	PEX7	YDR142C	463	n/a	chrIV 741,036	Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins WD repeat protein defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP)
32	SAP1	YER047C	463	n/a	chrV 245,156	Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system
33	SLX8	YER116C	463	n/a	chrV 395,760	Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex stimulated by prior attachment of SUMO to the substrate contains a C-terminal RING domain
34	YIL152W	YIL152W	463	n/a	chrIX 56,898	Putative protein of unknown function
35	YKE4	YIL023C	463	n/a	chrIX 309,906	Zinc transporter localizes to the ER null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family
36	PAU5	YFL020C	463	n/a	chrVI 99,415	Member of the seripauperin multigene family encoded mainly in subtelomeric regions induced during alcoholic fermentation induced by low temperature and also by anaerobic conditions negatively regulated by oxygen and repressed by heme
37	GLG2	YJL137C	463	n/a	chrX 155,556	Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside similar to mammalian glycogenin
38	YJR115W	YJR115W	463	n/a	chrX 640,196	Putative protein of unknown function
39	YJR154W	YJR154W	463	n/a	chrX 726,304	Putative protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
40	CCC1	YLR220W	463	n/a	chrXII 577,309	Putative vacuolar Fe2+/Mn2+ transporter suppresses respiratory deficit of yfh1 mutants, which lack the ortholog of mammalian frataxin, by preventing mitochondrial iron accumulation
41	YGL193C	YGL193C	463	n/a	chrVII 142,071	Haploid-specific gene repressed by a1-alpha2, turned off in sir3 null strains, absence enhances the sensitivity of rad52-327 cells to campothecin almost 100-fold
42	CDH1	YGL003C	463	n/a	chrVII 493,324	Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit targets the APC/C to specific substrates including Cdc20p, Ase1p, Cin8p and Fin1p
43	PAU4	YLR461W	463	n/a	chrXII 1,063,100	Member of the seripauperin multigene family encoded mainly in subtelomeric regions active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
44	YNL033W	YNL033W	463	n/a	chrXIV 573,426	Putative protein of unknown function
45	SSL2	YIL143C	463	n/a	chrIX 81,775	Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA involved in DNA repair homolog of human ERCC3
46	SPR6	YER115C	463	n/a	chrV 394,579	Protein of unknown function, expressed during sporulation not required for sporulation, but gene exhibits genetic interactions with other genes required for sporulation
47	PAU10	YDR542W	463	n/a	chrIV 1,523,430	Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions
48	EAR1	YMR171C	463	n/a	chrXIII 604,694	Specificity factor required for Rsp5p-dependent ubiquitination and sorting of specific cargo proteins at the multivesicular body mRNA is targeted to the bud via the mRNA transport system involving She2p
49	HER2	YMR293C	463	n/a	chrXIII 856,096	Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex involved in the formation of Q-tRNAQ required for remodeling of ER caused by Hmg2p overexpression similar to bacterial GatA glutamyl-tRNA amidotransferase
50	SSY1	YDR160W	463	n/a	chrIV 777,442	Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes