UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F59D12.5	F59D12.5	9e-78	chrX 15,646,886
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	R10E4.11	R10E4.11	n/a	chrIII 4,299,234	contains similarity to Pfam domain PF00096 (Zinc finger, C2H2 type)
4	rpb-11	W01G7.3	n/a	chrII 14,060,256	C. elegans RPB-11 protein; contains similarity to Pfam domain PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain contains similarity to Interpro domains IPR008193 (DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site), IPR011261 (DNA-directed RNA polymerase, dimerisation), IPR009025 (DNA-directed RNA polymerase, RBP11-like)
5	F48E3.2	F48E3.2	n/a	chrX 7,491,715	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
6	D2030.3	D2030.3	n/a	chrI 7,579,667	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
7	F54F2.7	F54F2.7	n/a	chrIII 8,806,716	contains similarity to Interpro domain IPR011053 (Single hybrid motif)
8	ZK1236.5	ZK1236.5	n/a	chrIII 8,431,825	ZK1236.5 encodes a protein with no obvious non-nematode homologs; either ZK1236.9, or ZK1236.5, or both proteins weakly inhibit DHC-1 in vivo; likewise, either ZK1236.5, or ZK1236.9, or both proteins are required in mass RNAi assays for normal osmoregulation and normally rapid growth.
9	C48B6.2	C48B6.2	n/a	chrI 6,917,161	contains similarity to Pfam domain PF01479 S4 domain contains similarity to Interpro domains IPR002942 (RNA-binding S4), IPR001912 (Ribosomal protein S4)
10	C27F2.4	C27F2.4	n/a	chrIII 4,959,381	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
11	R08F11.1	R08F11.1	n/a	chrV 3,781,014	contains similarity to Pfam domain PF04685 Protein of unknown function, DUF608 contains similarity to Interpro domains IPR006775 (Protein of unknown function DUF608), IPR014551 (Beta-glucosidase, GBA2 type), IPR008928 (Six-hairpin glycosidase-like)
12	M04C9.3	M04C9.3	n/a	chrI 9,353,710	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like), IPR000816 (Peptidase C15, pyroglutamyl peptidase I)
13	F07E5.5	F07E5.5	n/a	chrII 2,056,499	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR013084 (Zinc finger, CCHC retroviral-type), IPR001878 (Zinc finger, CCHC-type)
14	nhr-151	C06B8.3	n/a	chrV 15,484,320	C. elegans NHR-151 protein ;
15	mau-2	C09H6.3	n/a	chrI 8,127,936	mau-2 encodes an ortholog of budding yeast Scc4p, Drosophila CG4203, and human KIAA0892; MAU-2 is required (with PQN-85 and SCC-3) for normal mitotic chromosome segregation, and for cellular (e.g., neuronal) or axonal migration; MAU-2 is required for migration both embryonically and postembryonically, along both dorsoventral and longitudinal body axes; MAU-2 guides the axonal projection of AVM (and probably other neurons) by some cell-autonomous mechanism independent of SLT-1; MAU-2 is also required for normal larval development, locomotion, excretory canals and osmoregulation, phasmid morphology, and egg-laying; the primary sequences of MAU-2 and its Scc4-like orthologs are composed of tetratricopeptide repeats, and are highly divergent between yeast and metazoa; MAU-2 is expressed ubiquitously in embryos during late gastrulation, subsequently becoming restricted to neurons; mau-2 transcripts are abundant in oocytes, and maternal transcripts alone can support normal MAU-2 protein synthesis through the L3 larval stage (but not in L4 larvae or adults); MAU-2's N-terminal 371 residues of MAU-2 are its most conserved domain, and are sufficient to transgenically rescue mau-2 mutants; despite its behavioral phenotype, MAU-2 is thought to act early in development, since the uncoordinated phenotype of mau-2 mutants is maternal; while the uncoordinated phenotype of mau-2 mutants can be rescued either maternally or zygotically, the egg-laying phenotype of mau-2 mutants is purely zygotic; partially penetrant mau-2 dye-filling phenotypes occur on one side of the body, suggesting that MAU-2 acts on a whole side of an embryo at a time; while mau-2(RNAi) has no obvious early embryonic phenotype, joint mau-2/scc-3(RNAi) grossly deranges chromosomal segregation in early embryos, and mau-2(RNAi) enhances the lagging of anaphase chromosomes induced by pqn-85(RNAi).
16	scpl-2	F45E12.1	n/a	chrII 7,312,591	scpl-2 encodes a putative serine/threonine phosphatase, orthologous to budding yeast Nem1p and human DULLARD; SCPL-2 is expressed in pharynx and intestine; SCPL-2 is distantly similar to FCP-1 and SCPL-1, -3, and -4; by orthology, SCPL-2 is expected to localize to the nuclear envelope, to regulate nuclear membrane biogenesis, and to dephosphorylate the phosphatidic acid phosphatase ortholog H37A05.1.
17	exos-1	Y48A6B.5	n/a	chrIII 11,009,701	C. elegans EXOS-1 protein ; contains similarity to Drosophila melanogaster Flybase gene name is Csl4-PA;; FLYBASE:CG6249
18	K10E9.1	K10E9.1	n/a	chrI 196,071
19	F26D11.1	F26D11.1	n/a	chrV 7,982,245	contains similarity to Pfam domain PF01202 Shikimate kinase contains similarity to Interpro domains IPR000623 (Shikimate kinase), IPR006001 (Carbohydrate kinase, thermoresistant glucokinase)
20	F29A7.6	F29A7.6	n/a	chrII 2,752,187	contains similarity to Mus musculus M-phase phosphoprotein 6.; SW:Q9D1Q1
21	F44F1.4	F44F1.4	n/a	chrI 13,264,689	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
22	Y26D4A.8	Y26D4A.8	n/a	chrI 13,084,164	contains similarity to Bos taurus Myosin-10 (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb)s(Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellularsmyosin heavy chain, type B) (Non-muscle myosin heavy chain-B) (NMMHC-sB).; SW:Q27991
23	E04D5.2	E04D5.2	n/a	chrII 10,420,700	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
24	F39H11.1	F39H11.1	n/a	chrI 8,697,062	contains similarity to Pfam domain PF07572 Bucentaur or craniofacial development contains similarity to Interpro domains IPR011421 (Bucentaur or craniofacial development), IPR005413 (Low calcium response V antigen)
25	F52H2.3	F52H2.3	n/a	chrX 2,540,613
26	C53C11.1	C53C11.1	n/a	chrX 17,340,978	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
27	pfd-5	R151.9	n/a	chrIII 7,198,447	pfd-5 encodes a putative prefoldin 5 subunit, orthologous to human PFDN5 (OMIM:604899), that is required for normal microtubule growth, embryonic and larval viability, fertility, vulval development, and locomotion; PFD-5 is expressed in most, if not all, tissues; pfd-5(RNAi) animals show sterile progeny, larval arrest or lethality, uncoordination, and abnormal body shapes, and pfd-5(RNAi) embryos show a reduced microtubule growth rate.
28	C26E6.3	C26E6.3	n/a	chrIII 4,945,871	contains similarity to Pfam domain PF04078 Cell differentiation family, Rcd1-like contains similarity to Interpro domain IPR007216 (Cell differentiation proteins, Rcd1-like)
29	lin-25	F56H9.5	n/a	chrV 12,654,300	lin-25 encodes a novel transcription factor that is conserved in C. briggsae and C. remanei; during development, lin-25 functions downstream of let-60 ras to regulate fate specification and differentiation of a number of cell types such as the vulval precursor cells; targets of LIN-25 activity include the lin-39 Hox gene, whose transcriptional upregulation during vulval cell fate specification is dependent upon lin-25; LIN-25 is expressed in vulval precursor cells, hypodermal seam cells, and cells in the somatic gonad; LIN-25 is detected in nuclei, but also seen in the cytoplasm.
30	C01B10.4	C01B10.4	n/a	chrIV 6,630,045	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
31	F10G8.6	F10G8.6	n/a	chrI 10,047,224	F10G8.6 encodes an homolog of S. cerevisiae CFD1 (also known as YIL003W/DRE3), a putative P-loop ATPase conserved in eukaryotes and required in yeast for 4Fe-4S cluster assembly; F10G8.6 is also homologous to yeast NBP35/YGL091C; in C. elegans, F10G8.6 is required for normally rapid growth and maintenance of the germline; F10G8.6 protein was predicted to be mitochondrial on the basis of its phylogenetic profile.
32	end-3	F58E10.5	n/a	chrV 14,015,253	end-3 encodes a GATA zinc finger protein, paralogous to end-1, that helps specify mesoendodermal (as opposed to mesectodermal) lineages derived from the E blastomere.
33	F48A11.4	F48A11.4	n/a	chrII 214,905
34	sru-9	Y45F10B.11	n/a	chrIV 13,589,633	C. elegans SRU-9 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
35	nhr-258	C26B2.4	n/a	chrIV 8,045,986	C. elegans NHR-258 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	rod-1	F55G1.4	n/a	chrIV 7,481,969	C. elegans ROD-1 protein ; contains similarity to Caenorhabditis remanei Putative RoughDeal (Fragment).; TR:Q4TTM7
37	Y76G2A.2	Y76G2A.2	n/a	chrI 5,979,210
38	pro-1	R166.4	n/a	chrII 10,540,649	pro-1 encodes a WD-repeat-containing protein that is orthologous to Saccharomyces cerevisiae IPI3; pro-1 activity is required for ribosome biogenesis and specifically, for efficient processing of intervening sequence 2 (ITS2) from rRNA intermediates during 26S rRNA maturation; during development, pro-1 is essential for larval growth, fertility, and normal cell division patterns; in addition, pro-1 is required cell autonomously in the somatic gonad for proper spatial and temporal regulation of germline development and proliferation; a pro-1 promoter::gfp fusion construct reveals that pro-1 is widely expressed in the embryo as well as in every major post-embryonic lineage including the somatic gonad.
39	syn-13	F36F2.4	n/a	chrI 9,003,016	C. elegans SYN-13 protein; contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR010989 (t-SNARE), IPR006011 (Syntaxin, N-terminal), IPR000727 (Target SNARE coiled-coil region), IPR006012 (Syntaxin/epimorphin, conserved site)
40	F53H4.3	F53H4.3	n/a	chrX 15,886,572	contains similarity to Mus musculus Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).; SW:ATX1_MOUSE
41	K10C2.2	K10C2.2	n/a	chrX 6,433,006	contains similarity to Interpro domain IPR000832 (GPCR, family 2, secretin-like)
42	T08B2.4	T08B2.4	n/a	chrI 6,225,763
43	K07E8.7	K07E8.7	n/a	chrII 645,697	contains similarity to Pfam domain PF00849 RNA pseudouridylate synthase contains similarity to Interpro domains IPR006145 (Pseudouridine synthase), IPR006224 (Pseudouridine synthase, conserved site), IPR002942 (RNA-binding S4), IPR006225 (Pseudouridine synthase, RluD)
44	ZC239.16	ZC239.16	n/a	chrII 3,225,022	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
45	F45G2.9	F45G2.9	n/a	chrIII 13,436,244	contains similarity to Pfam domain PF01728 FtsJ-like methyltransferase contains similarity to Interpro domains IPR016448 (23S ribosomal RNA methyltransferase), IPR015507 (Ribosomal RNA methyltransferase J), IPR002877 (Ribosomal RNA methyltransferase RrmJ/FtsJ)
46	C14E2.1	C14E2.1	n/a	chrX 1,826,905
47	Y47H9C.7	Y47H9C.7	n/a	chrI 11,892,653	Y47H9C.7 is orthologous to the human gene EUKARYOTIC TRANSLATION INITIATION FACTOR 2B, SUBUNIT 2 (BETA, 39KD) (EIF2B2; OMIM:606454), which when mutated leads to disease.
48	str-255	C45H4.15	n/a	chrV 2,162,667	C. elegans STR-255 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000301 (CD9/CD37/CD63 antigen)
49	R12C12.5	R12C12.5	n/a	chrII 6,044,615	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
50	srd-68	F09C6.7	n/a	chrV 16,901,990	C. elegans SRD-68 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)