UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
2	glr-1	C06E1.4	0	chrIII 8,586,335	glr-1 encodes an AMPA (non-NMDA)-type ionotropic glutamate receptor subunit; GLR-1 activity is required for mediating the behavioral response to light nose touch and the frequency with which animals change locomotory direction in response to sensory cues such as food; GLR-1 and GLR-2, a second AMPA-type ionotropic glutatmate receptor, can interact to form functional heteromeric channels; GLR-1 is expressed in motorneurons and interneurons, including four of the five pairs of command interneurons that are required for locomotory control; in the ventral nerve cord and nerve ring, GLR-1 localizes to perinuclear structures in cell bodies and to punctate structures that appear to be glutamatergic postsynaptic specializations; proper GLR-1 localization in the anterior ventral nerve cord of older larvae and adults requires activity of the class I PDZ protein LIN-10; GLR-1 is ubiquitinated in vivo and its abundance at postsynaptic elements, which may influence postsynaptic strength, is regulated by ubiquitination.
3	R03H10.6	R03H10.6	n/a	chrII 4,172,578	contains similarity to Pfam domain PF01336 OB-fold nucleic acid binding domain contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR004365 (Nucleic acid binding, OB-fold, tRNA/helicase-type)
4	B0198.3	B0198.3	n/a	chrX 12,045,895	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
5	F32B6.9	F32B6.9	n/a	chrIV 9,904,788	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
6	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
7	Y69H2.2	Y69H2.2	n/a	chrV 18,632,391	contains similarity to Pfam domains PF00008 (EGF-like domain) (5), PF00858 (Amiloride-sensitive sodium channel) , PF07974 (EGF-like domain) (2)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR001873 (Na+ channel, amiloride-sensitive)
8	C25G6.4	C25G6.4	n/a	chrX 1,248,831
9	M60.6	M60.6	n/a	chrX 8,250,273
10	C31A11.7	C31A11.7	n/a	chrV 16,312,313	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
11	hst-3.1	F40H3.5	n/a	chrII 6,168,467	C. elegans HST-3.1 protein; contains similarity to Pfam domain PF00685 Sulfotransferase domain contains similarity to Interpro domain IPR000863 (Sulphotransferase)
12	M163.5	M163.5	n/a	chrX 14,475,017	contains similarity to Interpro domain IPR008995 ()
13	nlr-1	F20B10.1	n/a	chrIV 12,174,554	C. elegans NLR-1 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF02210 (Laminin G domain) (2), PF00054 (Laminin G domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR001791 (Laminin G), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR012680 (Laminin G, subdomain 2), IPR008985 (Concanavalin A-like lectin/glucanase), IPR012679 (Laminin G, subdomain 1)
14	srx-36	T01C4.6	n/a	chrV 7,130,371	C. elegans SRX-36 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
15	M01G4.1	M01G4.1	n/a	chrIII 6,665,107
16	ugt-56	T04H1.8	n/a	chrV 12,260,070	C. elegans UGT-56 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
17	glb-2	C06E4.7	n/a	chrIV 7,262,720	glb-2 encodes a globin; glb-2 transcription is higher in L3 and dauers than in young adults; glb-2 has no obvious function in mass RNAi assays.
18	Y76G2A.2	Y76G2A.2	n/a	chrI 5,979,210
19	srw-117	C44C3.6	n/a	chrV 2,982,800	C. elegans SRW-117 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
20	F47G4.5	F47G4.5	n/a	chrI 14,061,493	F47G4.5 encodes a paralog of MEI-2 that, like MEI-2, binds MEI-1 in vitro; F47G4.5 might thus be an alternative ligand of MEI-1 in vivo.
21	T07F12.3	T07F12.3	n/a	chrX 4,887,726	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
22	F56D2.5	F56D2.5	n/a	chrIII 5,579,782	contains similarity to Pfam domains PF05773 (RWD domain) , PF01485 (IBR domain) (2)contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR006575 (RWD), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR002867 (Zinc finger, C6HC-type)
23	T14G12.6	T14G12.6	n/a	chrX 3,758,129	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
24	K03B8.6	K03B8.6	n/a	chrV 11,408,332	contains similarity to Interpro domain IPR000585 (Hemopexin)
25	F30A10.1	F30A10.1	n/a	chrI 9,473,896	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
26	lin-32	T14F9.5	n/a	chrX 2,229,639	lin-32 encodes a basic helix-loop-helix transcription factor that is required for development of several types of neurons, including the touch receptor neurons and the male sensory ray neurons.
27	cah-1	F54D8.4	n/a	chrIII 5,084,208	cah-1 encodes a member of the carbonic anhydrase family.
28	str-20	C05E4.2	n/a	chrV 757,182	C. elegans STR-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	dct-10	Y38H6C.5	n/a	chrV 20,503,211	C. elegans DCT-10 protein; contains similarity to Pfam domains PF03732 (Retrotransposon gag protein) , PF00098 (Zinc knuckle) contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR005162 (Retrotransposon gag protein), IPR001878 (Zinc finger, CCHC-type)
30	E04D5.2	E04D5.2	n/a	chrII 10,420,700	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
31	sor-3	C04E7.2	n/a	chrX 355,777	sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins; during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size; SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons; in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway; sor-3 and sop-2 also function together to regulate progression through larval development; a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus.
32	F57B7.2	F57B7.2	n/a	chrV 11,442,786	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
33	C01B10.7	C01B10.7	n/a	chrIV 6,638,773	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
34	C09F12.2	C09F12.2	n/a	chrX 11,055,383	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23C46
35	ZK418.7	ZK418.7	n/a	chrIII 7,079,862	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003842 (Vacuolating cytotoxin), IPR000276 (GPCR, rhodopsin-like)
36	C05G5.3	C05G5.3	n/a	chrX 14,751,355	contains similarity to Homo sapiens Isoform 1 of Matrix-remodeling-associated protein 7; ENSEMBL:ENSP00000348050
37	ZK678.3	ZK678.3	n/a	chrX 15,748,766	contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal)
38	zig-1	K10C3.3	n/a	chrI 9,848,900	zig-1 encodes a predicted transmembrane protein that is a member of the immunoglobulin superfamily of proteins; a zig-1::gfp reporter fusion is expressed in most neurons, including the PVT interneuron, as well as in body wall muscle; zig-1::gfp expression begins during the L1 larval stage of development.
39	C53A5.11	C53A5.11	n/a	chrV 14,563,580	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF07646 (Kelch motif) (3)contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
40	fbxa-52	F07G6.6	n/a	chrX 1,710,748	C. elegans FBXA-52 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
41	unc-122	F11C3.2	n/a	chrI 14,873,757	unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known.
42	C26E1.1	C26E1.1	n/a	chrV 13,297,767	contains similarity to Rattus norvegicus GLUT4 vesicle protein.; TR:Q9Z1X1
43	nhr-84	T06C12.7	n/a	chrV 15,878,178	C. elegans NHR-84 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	K04G11.4	K04G11.4	n/a	chrX 14,351,065	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR000694 (Proline-rich region), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR001632 (G-protein, beta subunit), IPR015943 (WD40/YVTN repeat-like)
45	ubc-19	Y69H2.6	n/a	chrV 18,688,049	ubc-19 encodes a predicted conjgating enzyme (UBCs/E2s) of the ubiquitin-conjugation system with a potentially low effect on embryonic viability, based on RNAi analysis.
46	mec-6	W02D3.3	n/a	chrI 6,726,624	mec-6 is homologous to the human PARAOXONASE 1 gene (PON1, OMIM:168820), which in some allelic forms is associated with susceptibility to coronary artery disease; MEC-6 protein interacts physically with the MEC-4 degenerin ion channel, is colocalized with it in vivo, and is required for MEC-4 punctate expression along touch-receptor neural processes.
47	cec-1	ZK1236.2	n/a	chrIII 8,427,378	cec-1 encodes a nuclear protein with a chromodomain that is ubiquitously expressed in somatic cells, but is dispensable for embryonic survival or gross adult morphology.
48	ncs-1	C44C1.3	n/a	chrX 961,929	The ncs-1 gene encodes a neuronal calcium sensor protein that, along with calcium, is essential for thermotaxis along isothermal paths in thermal gradients.
49	T05H4.10	T05H4.10	n/a	chrV 6,420,809	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
50	gpa-6	F48C11.1	n/a	chrX 13,192,522	gpa-6 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that affects response to water-soluble odorants; it is expressed in AWA amphid neurons, the PHB sensory cell, and (at low levels) in ASI amphid neurons.