UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C17B7.4	C17B7.4	9.999999999999999e-116	chrV 3,339,687	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR003559 (Cytolethal distending toxin C), IPR002542 (Protein of unknown function DUF19)
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	T28A11.5	T28A11.5	3.9999999999999996e-100	chrV 3,270,895	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR003559 (Cytolethal distending toxin C), IPR002542 (Protein of unknown function DUF19)
4	F53F4.7	F53F4.7	n/a	chrV 13,613,185	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
5	C07A9.8	C07A9.8	n/a	chrIII 9,688,522	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
6	ins-11	C17C3.4	n/a	chrII 5,556,897	ins-11 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-11 is one of 38 insulin-like peptides in C. elegans and is expressed in the labial sensory neurons, the nerve ring, and other neurons; although the precise role of INS-11 in C. elegans development is not yet clear, loss of INS-11 function via RNA-mediated interference can result in animals that are smaller than wild type (Sma).
7	dhs-31	T04B2.6	n/a	chrIV 10,040,250	C. elegans DHS-31 protein; contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
8	tag-38	B0222.4	n/a	chrV 9,145,742	C. elegans TAG-38 protein; contains similarity to Pfam domains PF00282 (Pyridoxal-dependent decarboxylase conserved domain) , PF00266 (Aminotransferase class-V) contains similarity to Interpro domains IPR002129 (Pyridoxal phosphate-dependent decarboxylase), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
9	dhs-26	ZK816.5	n/a	chrX 3,361,621	dhs-26 encodes a short-chain dehydrogenase predicted to be mitochondrial.
10	T19D12.3	T19D12.3	n/a	chrII 6,660,581
11	C32H11.3	C32H11.3	n/a	chrIV 12,919,384	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
12	srw-120	K12D9.5	n/a	chrV 2,995,551	C. elegans SRW-120 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
13	ins-7	ZK1251.2	n/a	chrIV 9,682,219	ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity.
14	ttr-1	K03H1.6	n/a	chrIII 9,929,635	ttr-1 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; although TTR-1 belongs to a family of apparently nematode-specific proteins whose function is not yet known, loss of ttr-1 function via RNAi can result in enhanced dauer formation and daf-16-dependent lifespan extension.
15	F47B8.4	F47B8.4	n/a	chrV 14,324,002	contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR012336 (Thioredoxin-like fold)
16	C32F10.4	C32F10.4	n/a	chrI 5,809,249
17	cnc-4	R09B5.9	n/a	chrV 1,447,465	cnc-4 encodes one of six C. elegans caenacin peptides; cnc-4 expression is strongly induced after infection by the fungus Drechmeria coniospora, suggesting that it functions as a secreted antimicrobial peptide in the innate immune response.
18	K01A2.10	K01A2.10	n/a	chrII 322,278	contains similarity to Homo sapiens Coiled-coil domain-containing protein 92; ENSEMBL:ENSP00000238156
19	srw-33	T26H5.5	n/a	chrV 15,450,551	C. elegans SRW-33 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000276 (GPCR, rhodopsin-like)
20	thn-2	F28D1.5	n/a	chrIV 12,383,557	C. elegans THN-2 protein; contains similarity to Pfam domain PF00314 Thaumatin family contains similarity to Interpro domain IPR001938 (Thaumatin, pathogenesis-related)
21	C36C5.12	C36C5.12	3.9999999999999994e-19	chrV 3,158,933	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
22	C03G6.6	C03G6.6	n/a	chrV 7,358,148	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
23	F46A8.7	F46A8.7	n/a	chrI 11,238,164	contains similarity to Homo sapiens hypothetical protein MGC35285; ENSEMBL:ENSP00000279688
24	F55G1.7	F55G1.7	n/a	chrIV 7,467,673
25	tag-243	T04A8.4	n/a	chrIII 4,686,618	C. elegans TAG-243 protein; contains similarity to Interpro domain IPR000637 (HMG-I and HMG-Y, DNA-binding)
26	skr-5	F47H4.10	n/a	chrV 17,348,283	The skr-5 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-5(RNAi) animals are at least superficially normal.
27	F18G5.6	F18G5.6	n/a	chrX 9,263,128
28	F11C1.4	F11C1.4	n/a	chrX 12,979,059	contains similarity to Drosophila melanogaster Flybase gene name is CG9186-PA;; FLYBASE:CG9186
29	F35F10.1	F35F10.1	n/a	chrV 3,317,203	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
30	F36G9.7	F36G9.7	n/a	chrV 15,968,760	contains similarity to Methanosarcina mazei Hypothetical protein MM0083.; TR:Q8Q0Q3
31	fbxa-24	F54D10.2	n/a	chrII 3,817,370	C. elegans FBXA-24 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
32	C17G10.7	C17G10.7	n/a	chrII 5,607,281
33	ZC196.2	ZC196.2	n/a	chrV 8,740,693	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
34	F48G7.2	F48G7.2	n/a	chrV 637,034
35	ilys-3	C45G7.3	n/a	chrIV 2,464,939	C. elegans ILYS-3 protein; contains similarity to Pfam domain PF05497 Destabilase contains similarity to Interpro domain IPR008597 (Destabilase)
36	ttr-5	C40H1.5	n/a	chrIII 9,330,525	C40H1.5 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of C40H1.5 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
37	F49H6.5	F49H6.5	n/a	chrV 17,024,380	The F49H6.5 gene encodes a homolog of the human gene MOCS1A, which when mutated leads to molybdenum cofactor deficiency (OMIM:252150).
38	fat-5	W06D12.3	n/a	chrV 17,725,852	fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1.
39	F07C3.9	F07C3.9	n/a	chrV 9,254,456
40	C13A2.3	C13A2.3	n/a	chrV 7,283,523	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
41	F48C1.8	F48C1.8	n/a	chrI 5,335,938	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein)
42	F26D11.2	F26D11.2	n/a	chrV 7,960,124
43	F53A9.7	F53A9.7	n/a	chrX 8,716,682	contains similarity to Interpro domain IPR002395 (HMW kininogen)
44	T24F1.5	T24F1.5	n/a	chrII 11,319,376	contains similarity to Bombyx mori Lebocin 1/2 precursor.; SW:LEB1_BOMMO
45	C06E4.8	C06E4.8	n/a	chrIV 7,284,853	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
46	spp-20	K04A8.8	n/a	chrV 6,557,433	C. elegans SPP-20 protein; contains similarity to Pfam domain PF05184 Saposin-like type B, region 1 contains similarity to Interpro domains IPR011001 (Saposin-like), IPR007856 (Saposin-like type B, 1), IPR008139 (Saposin B)
47	F53A9.1	F53A9.1	n/a	chrX 8,711,652	contains similarity to Interpro domains IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR002395 (HMW kininogen)
48	grd-9	C04E6.6	n/a	chrV 5,896,978	grd-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-9 is weakly required for normal molting; GRD-9 is also required for normal growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
49	B0554.1	B0554.1	n/a	chrV 438,570
50	tyr-3	F21C3.2	n/a	chrI 7,276,425	C. elegans TYR-3 protein; contains similarity to Pfam domains PF00264 (Common central domain of tyrosinase) , PF01549 (ShK domain-like) (4)contains similarity to Interpro domains IPR008922 (Di-copper centre-containing), IPR002227 (Tyrosinase), IPR003582 (Metridin-like ShK toxin)