UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C27F2.8	C27F2.8	0	chrIII 4,994,766	contains similarity to Interpro domain IPR000694 (Proline-rich region)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
4	C44H4.1	C44H4.1	n/a	chrX 14,574,334	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
5	clec-263	F26F2.6	n/a	chrV 20,571,518	C. elegans CLEC-263 protein; contains similarity to Pfam domains PF08277 (PAN-like domain) (2), PF00024 (PAN domain) contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
6	col-75	K03H9.2	n/a	chrII 6,426,809	C. elegans COL-75 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
7	T03D8.7	T03D8.7	n/a	chrV 20,811,735	contains similarity to Homo sapiens Uncharacterized protein ENSP00000381489; ENSEMBL:ENSP00000335483
8	K09B3.1	K09B3.1	n/a	chrIV 3,795,512	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
9	acr-2	K11G12.2	n/a	chrX 6,705,942	A homolog of a non-alpha type nicotinic acetylcholine receptor subunit that forms a functional channel when co-expressed with the unc-38 alpha subunit.
10	R08B4.3	R08B4.3	n/a	chrX 11,119,911	contains similarity to Homo sapiens 23 kDa protein; VG:OTTHUMP00000170038
11	T23C6.5	T23C6.5	n/a	chrX 17,156,542	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR004827 (Basic-leucine zipper (bZIP) transcription factor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
12	dpy-22	F47A4.2	n/a	chrX 9,816,134	dpy-22 encodes a broadly expressed protein, homologous to the human transcriptional mediator protein TRAP230, which is involved in WNT and RAS signaling, as well as in dosage compensation; DPY-22 has a C-terminal glutamine-rich domain that is dispensable for inhibition of RAS-dependent cell differentiation, but is required for inhibition of BAR-1-dependent gene expression.
13	ltd-1	K02C4.4	n/a	chrII 8,090,520	ltd-1 encodes a protein with LIM and transglutaminase domains; LTD-1 is homologous to the mouse KY protein (MGI:96709, mutated in kyphoscoliosis), and to the HILLARIN protein of Hirudo medicinalis, found at axon hillocks; ltd-1 is expressed in hypodermal cells from the twofold stage embryo to adulthood, but has no obvious function in mass RNAi assays.
14	abch-1	C56E6.5	n/a	chrII 6,530,223	C. elegans ABCH-1 protein; contains similarity to Interpro domain IPR003439 (ABC transporter-like)
15	fbxa-153	B0391.5	n/a	chrV 15,608,029	fbxa-153 encodes a protein with an N-terminal F-box domain and a C-terminal FTH domain; FBXA-153 has no obvious non-nematode orthologs; FBXA-153 shares N-terminal UNC-13 binding, and thus may share at least some functions, with ERI-1, W04D2.6, and Y55F3AM.13; FBXA-153 has no obvious function in mass RNAi assays.
16	ift-74	C18H9.8	n/a	chrII 6,681,205	C. elegans IFT-74 protein; contains similarity to Interpro domains IPR010989 (t-SNARE), IPR000694 (Proline-rich region)
17	srg-67	ZC317.4	n/a	chrV 5,462,245	C. elegans SRG-67 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
18	C34D4.14	C34D4.14	n/a	chrIV 7,139,438	contains similarity to Pfam domains PF06701 (Mib_herc2) , PF07738 (Sad1 / UNC-like C-terminal) , PF02985 (HEAT repeat) , PF00023 (Ankyrin repeat) (2), PF00632 (HECT-domain (ubiquitin-transferase)) contains similarity to Interpro domains IPR012919 (Sad1/UNC-like, C-terminal), IPR011989 (Armadillo-like helical), IPR000569 (HECT), IPR008979 (Galactose-binding like), IPR002110 (Ankyrin), IPR010606 (Mib-herc2), IPR016024 (Armadillo-type fold)
19	F14H12.2	F14H12.2	n/a	chrX 4,351,596
20	ttr-11	F46B3.3	n/a	chrV 20,599,260	C. elegans TTR-11 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
21	F15D3.4	F15D3.4	n/a	chrI 11,568,010	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
22	F22E5.1	F22E5.1	n/a	chrII 2,676,663	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
23	C33D9.8	C33D9.8	n/a	chrIV 8,784,995	contains similarity to Interpro domains IPR000533 (Tropomyosin), IPR009053 (Prefoldin)
24	T20F7.5	T20F7.5	n/a	chrX 16,850,352	contains similarity to Interpro domain IPR000694 (Proline-rich region)
25	F14B8.6	F14B8.6	n/a	chrX 6,930,764
26	ZK265.8	ZK265.8	n/a	chrI 8,271,989	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
27	rsr-1	F28D9.1	n/a	chrI 11,179,945	C. elegans RSR-1 protein; contains similarity to Pfam domain PF01480 PWI domain contains similarity to Interpro domains IPR002483 (Splicing factor PWI), IPR000694 (Proline-rich region), IPR005819 (Histone H5), IPR002185 (Dopamine D4 receptor)
28	T26G10.4	T26G10.4	n/a	chrIII 9,420,953	contains similarity to Forficula auricularia Reverse transcriptase (Fragment).; TR:O44323
29	fbxa-154	B0391.6	n/a	chrV 15,603,958	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
30	vab-9	T22C8.8	n/a	chrII 8,636,902	vab-9 encodes a claudin homolog orthologous to human brain cell membrane protein 1 (BCMP1) and Drosophila CG6982; VAB-9 colocalizes with HMP-1 to an apical layer of the adherens junctions of all epithelial cells, one layer more apically than AJM-1; vab-9 mutants have disorganized F-actin at the adherens junction, implying that VAB-9 links junctions to circumferential actin filaments; VAB-9 is also expressed in the nerve ring; VAB-9 requires the cadherin HMR-1 to localize to the cell membrane, and both alpha-catenin (HMP-1) and beta-catenin (HMP-2) to remain at the cell junction after membrane localization.
31	F01G10.7	F01G10.7	n/a	chrIV 10,240,539	contains similarity to Pfam domains PF04083 (ab-hydrolase associated lipase region) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR006693 (AB-hydrolase associated lipase region), IPR000073 (Alpha/beta hydrolase fold-1), IPR008262 (Lipase, active site)
32	C39F7.5	C39F7.5	n/a	chrV 1,267,440	contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold)
33	tag-293	C03G6.13	n/a	chrV 7,355,612	C. elegans TAG-293 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
34	C34F6.10	C34F6.10	n/a	chrX 11,233,244	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR000694 (Proline-rich region)
35	F40A3.1	F40A3.1	n/a	chrV 7,893,499
36	fbxa-141	D1025.3	n/a	chrX 14,512,622	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
37	srd-45	F17A2.7	n/a	chrX 12,329,674	C. elegans SRD-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	F28G4.3	F28G4.3	n/a	chrV 16,286,908	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
39	gcy-3	R134.1	n/a	chrII 9,504,941	gcy-3 is predicted to encode a guanylate cyclase.
40	rhgf-1	F13E6.6	n/a	chrX 10,704,787	rhgf-1 encodes an RGS RhoGEF (Regulator of G-protein Signaling Rho Guanine Nucleotide Exchange Factor); RHGF-1 functions within cholingergic motor neurons in one of four G-protein-mediated signaling pathways that control locomotion via regulation of acetylcholine (ACh) release at neuromuscular junctions; in regulating ACh release, RHGF-1 functions downstream of the C. elegans Galpha12 ortholog, GPA-12, and upstream of the Rho GTPase ortholog, RHO-1; additionally, rhgf-1 activity is required for normal mechanosensory behavior, egg laying, and embryonic development; an rhgf-1 reporter fusion is expressed in ventral cord motor neurons as well as several head neurons.
41	srt-72	C36C5.9	n/a	chrV 3,148,851	C. elegans SRT-72 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000215 (Protease inhibitor I4, serpin)
42	R07B1.5	R07B1.5	n/a	chrX 9,865,660	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
43	Y57G11C.21	Y57G11C.21	n/a	chrIV 14,846,701	contains similarity to Interpro domain IPR000358 (Ribonucleotide reductase)
44	col-123	W08D2.6	n/a	chrIV 9,822,477	col-123 is homologous to the human gene A TYPE IV COLLAGEN (COL6A1; OMIM:303631), which when mutated is sometimes associated with diffuse leiomyomatosis.
45	srw-138	C44C3.3	n/a	chrV 2,962,370	C. elegans SRW-138 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
46	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
47	dpy-28	Y39A1B.3	n/a	chrIII 10,770,127	dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1.
48	K02H11.4	K02H11.4	n/a	chrV 1,529,803	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
49	tba-9	F40F4.5	n/a	chrX 3,254,559	tba-9 encodes one of nine C. elegans alpha tubulins; by homology, TBA-9 is predicted to be a component of microtubules; as loss of tba-9 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, TBA-9 likely functions redundantly with other alpha tubulins as a basic component of cellular architecture that may play additional roles in processes such as cell division, cell movement, and intracellular transport.
50	set-30	ZC8.3	n/a	chrX 5,001,358	set-30 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-30 is paralogous to SET-10, SET-14, and SET-18; neither set-30(gk314) nor set-30(RNAi) have any obvious phenotypes.