UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C34F6.8	C34F6.8	0	chrX 11,216,944	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004790 (Isocitrate dehydrogenase NADP-dependent, eukaryotic), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
2	C36B7.6	C36B7.6	n/a	chrX 7,098,999	contains similarity to Pfam domain PF05602 Cleft lip and palate transmembrane protein 1 (CLPTM1) contains similarity to Interpro domain IPR008429 (Cleft lip and palate transmembrane 1)
3	M02G9.1	M02G9.1	n/a	chrII 10,330,867	contains similarity to Pfam domain PF02363 Cysteine rich repeat contains similarity to Interpro domains IPR003341 (Cysteine rich repeat, tripleX), IPR015333 (Pollen allergen ole e 6)
4	M01A10.3	M01A10.3	n/a	chrI 5,549,799	contains similarity to Pfam domain PF05817 Ribophorin II (RPN2) contains similarity to Interpro domain IPR008814 (Ribophorin II)
5	C06G1.5	C06G1.5	n/a	chrX 16,640,570	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
6	F22G12.4	F22G12.4	n/a	chrI 13,157,287	contains similarity to Pfam domains PF01363 (FYVE zinc finger) , PF00023 (Ankyrin repeat) (17)contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002110 (Ankyrin), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
7	T07G12.3	T07G12.3	n/a	chrIV 10,535,145	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
8	C05E11.7	C05E11.7	n/a	chrX 4,583,603
9	F53H8.3	F53H8.3	n/a	chrX 940,562	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
10	clec-53	T03F1.10	n/a	chrI 3,872,447	C. elegans CLEC-53 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR002352 (Eosinophil major basic protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
11	his-33	F17E9.13	n/a	chrIV 8,335,508	his-33 encodes an H2A histone; by homology, HIS-33 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-33 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
12	K02B12.7	K02B12.7	n/a	chrI 8,528,009	contains similarity to Pfam domain PF01412 Putative GTPase activating protein for Arf contains similarity to Interpro domain IPR001164 (Arf GTPase activating protein)
13	pyr-1	D2085.1	n/a	chrII 8,654,903	pyr-1 is orthologous to the human gene CARBAMYL PHOSPHATE SYNTHETASE I (CPS1, which when mutated leads to hyperammonemia (OMIM:237300); PYR-1 protein is predicted to be mitochondrial with 68% accuracy.
14	F15D4.5	F15D4.5	n/a	chrII 13,246,445	contains similarity to Interpro domain IPR001878 (Zinc finger, CCHC-type)
15	W02B12.11	W02B12.11	n/a	chrII 11,474,835	contains similarity to Pfam domain PF02709 Galactosyltransferase contains similarity to Interpro domain IPR003859 (Metazoa galactosyltransferase)
16	rab-11.1	F53G12.1	n/a	chrI 109,369	rab-11.1 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; RAB-11.1 activity is required for completion of the final stages of cytokinesis during early embryogenesis and for efficient uptake of yolk proteins during oocyte development; RAB-11.1 is also required for normal peripheral localization of nuclei in the synctial germ cell in the ovary.
17	C01B10.10	C01B10.10	n/a	chrIV 6,626,165	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR002410 (Peptidase S33, prolyl aminopeptidase), IPR002018 (Carboxylesterase, type B)
18	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
19	tag-257	F46G11.3	n/a	chrX 5,784,865	C. elegans TAG-257 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
20	B0416.1	B0416.1	n/a	chrX 9,307,010	contains similarity to Pfam domain PF07810 TMC domain contains similarity to Interpro domain IPR012496 (TMC)
21	gosr-2.1	B0272.2	n/a	chrX 9,440,914	C. elegans GOSR-2.1 protein; contains similarity to Pfam domain PF05008 Vesicle transport v-SNARE protein contains similarity to Interpro domain IPR007705 (Vesicle transport v-SNARE)
22	drr-1	F45H10.4	n/a	chrII 13,495,384	C. elegans DRR-1 protein; contains similarity to Interpro domain IPR008253 (Marvel)
23	K11G9.2	K11G9.2	n/a	chrV 6,675,280	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
24	F46C8.8	F46C8.8	n/a	chrX 7,552,792
25	gei-15	M03A8.4	n/a	chrX 6,821,678	C. elegans GEI-15 protein ;
26	C31E10.7	C31E10.7	n/a	chrX 14,002,346	C31E10.7 is orthologous to the human gene UNKNOWN (PROTEIN FOR MGC:10230) (CYB5; OMIM:250790), which when mutated leads to disease.
27	C03H12.1	C03H12.1	n/a	chrX 15,692,830	contains similarity to Interpro domain IPR012336 (Thioredoxin-like fold)
28	maoc-1	E04F6.3	n/a	chrII 7,196,834	maoc-1 encodes an ortholog of human HSD17B4 (OMIM:601860, mutated in D-bifunctional protein deficiency); MAOC-1 contains a MaoC-like domain found in diverse enzymes (HSD17B4, peroxisomal hydratase-dehydrogenase-epimerase, and the fatty acid synthase beta subunit) and by homology, is predicted to function in peroxisomal fatty acid beta-oxidation; loss of maoc-1 activity via RNAi results in lifespan extension, increased fat content, and an increased susceptibility to pathogens.
29	F46C5.9	F46C5.9	n/a	chrII 8,809,612	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
30	nhr-267	H22D14.1	n/a	chrIV 9,285,626	C. elegans NHR-267 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	R04B3.3	R04B3.3	n/a	chrX 2,474,889
32	F08G2.7	F08G2.7	n/a	chrII 13,838,597	contains similarity to Saccharomyces cerevisiae Suppresor of mar1-1 (sir2) mutation; SGD:YDR310C
33	K08F11.5	K08F11.5	n/a	chrIV 4,714,405	contains similarity to Pfam domains PF08356 (EF hand associated) , PF08355 (EF hand associated) , PF00071 (Ras family) , PF00036 (EF hand) (2), PF08477 (Miro-like protein) (2)contains similarity to Interpro domains IPR013566 (EF hand associated, type-1), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily), IPR013567 (EF hand associated, type-2)
34	C11H1.5	C11H1.5	n/a	chrX 14,300,542	contains similarity to Pfam domain PF00090 Thrombospondin type 1 domain contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
35	F49C12.9	F49C12.9	n/a	chrIV 9,315,482	contains similarity to Pfam domain PF00627 UBA/TS-N domain contains similarity to Interpro domains IPR009060 (UBA-like), IPR000449 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)
36	acl-8	T05H4.1	n/a	chrV 6,451,547	C. elegans ACL-8 protein; contains similarity to Pfam domain PF01553 Acyltransferase contains similarity to Interpro domain IPR002123 (Phospholipid/glycerol acyltransferase)
37	T11G6.4	T11G6.4	n/a	chrIV 10,850,812	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
38	gly-13	B0416.6	n/a	chrX 9,295,081	gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates; gly-13 is expressed throughout development in many cell types; gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14.
39	K07E3.2	K07E3.2	n/a	chrX 8,105,875
40	B0286.3	B0286.3	n/a	chrII 4,371,091	contains similarity to Pfam domains PF01259 (SAICAR synthetase) , PF00731 (AIR carboxylase) contains similarity to Interpro domains IPR001636 (SAICAR synthetase), IPR000031 (1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase), IPR013816 (ATP-grasp fold, subdomain 2)
41	Y54E5A.1	Y54E5A.1	n/a	chrI 14,690,180	contains similarity to Pfam domains PF00487 (Fatty acid desaturase) , PF08557 (Sphingolipid Delta4-desaturase (DES)) contains similarity to Interpro domains IPR013866 (Sphingolipid delta4-desaturase, N-terminal), IPR010257 (Fatty acid desaturase, type 1, N-terminal), IPR011388 (Sphingolipid delta4-desaturase), IPR005804 (Fatty acid desaturase, type 1)
42	pcp-2	F23B2.12	n/a	chrIV 9,162,862	C. elegans PCP-2 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domains IPR008758 (Peptidase S28), IPR000258 (Bacterial ice-nucleation proteins octamer repeat)
43	B0303.2	B0303.2	n/a	chrIII 8,685,551	contains similarity to Pfam domain PF01234 NNMT/PNMT/TEMT family contains similarity to Interpro domain IPR000940 (Methyltransferase, NNMT/PNMT/TEMT)
44	his-7	F45F2.4	n/a	chrV 8,533,548	his-7 encodes an H2A histone.
45	B0393.5	B0393.5	n/a	chrIII 4,772,641	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) (6), PF06119 (Nidogen-like) (2)contains similarity to Interpro domains IPR003886 (Nidogen, extracellular region), IPR001438 (EGF-like, type 2), IPR001881 (EGF-like calcium-binding), IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR013091 (EGF calcium-binding), IPR006210 (EGF)
46	snx-1	C05D9.1	n/a	chrX 1,130,709	C. elegans SNX-1 protein; contains similarity to Pfam domains PF09325 (Vps5 C terminal like) , PF00787 (PX domain) contains similarity to Interpro domains IPR001683 (Phox-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR015404 (Vps5 C terminal like)
47	his-3	T10C6.12	n/a	chrV 16,040,965	his-3 encodes an H2A histone; by homology, HIS-3 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-3 is a replication-dependent histone locus that resides in the HIS1 cluster on chromosome V.
48	K11B4.1	K11B4.1	n/a	chrI 14,796,015	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
49	F46H5.4	F46H5.4	n/a	chrX 7,249,770	contains similarity to Pfam domain PF06920 Dedicator of cytokinesis contains similarity to Interpro domains IPR011608 (PRD), IPR002052 (N-6 adenine-specific DNA methylase, conserved site), IPR010703 (Dedicator of cytokinesis), IPR016024 (Armadillo-type fold), IPR000008 (C2 calcium-dependent membrane targeting)
50	cnx-1	ZK632.6	n/a	chrIII 9,815,658	cnx-1 encodes the C. elegans ortholog of calnexin, a type I Ca2+-binding integral membrane protein of the endoplasmic reticulum (ER); CNX-1 binds calcium and is predicted to function as a molecular chaperone required for glycoprotein folding and maturation as well as regulation of intracellular calcium homeostasis; in C. elegans, cnx-1 activity is required at 25 degrees C for wild-type levels of fertility and normal embryonic and larval development; cnx-1 activity is also required for maintaining viability in response to ER stress; in addition, cnx-1(RNAi) can suppress necrotic-like cell death induced by hyperactivated MEC-4 and DEG-1 ion channels, suggesting that CNX-1 also plays a role in regulating necrotic cell death; CNX-1 expression is first detected ubiquitously in the early embryo, with expression then becoming restricted to embryonic head and tail regions; post-embryonic expression is seen in the excretory cell, head and tail neurons, spermatheca, intestine, germ cells, and spicules in the male tail; antibody staining of early embryos indicates that CNX-1 localizes to the endoplasmic reticulum; in regulating reproduction at 25 degrees C, cnx-1 functions redundantly with crt-1, which encodes calreticulin, an additional Ca2+-binding ER chaperone protein.