UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	skr-16	C42D4.6	2.9999999999999998e-90	chrIV 7,169,011	The skr-16 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-16(RNAi) animals are at least superficially normal.
2	T09E11.10	T09E11.10	n/a	chrI 12,346,532	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
3	W03G1.4	W03G1.4	n/a	chrIV 509,467	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
4	C56C10.10	C56C10.10	n/a	chrII 6,593,325	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF00515 (Tetratricopeptide repeat) contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
5	taf-3	C11G6.1	n/a	chrX 16,334,113	taf-3 encodes the C. elegans ortholog of mammalian TAF3(TAFII140), a component of the RNA polymerase II TFIID transcription complex; TAF-3 contains a histone fold-like domain in its N-terminus and by homology, is predicted to function in transcriptional regulation; however, as loss of taf-3 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of taf-3 in C. elegans development and/or behavior is not yet known.
6	F14H3.9	F14H3.9	n/a	chrV 16,068,329	contains similarity to Pfam domain PF03236 (Domain of unknown function DUF263)
7	T01G6.10	T01G6.10	n/a	chrV 502,683	contains similarity to Pfam domains PF01370 (NAD dependent epimerase/dehydratase family) , PF00106 (short chain dehydrogenase) contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR001509 (NAD-dependent epimerase/dehydratase), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
8	B0564.4	B0564.4	n/a	chrIV 13,112,036	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
9	W01A11.2	W01A11.2	n/a	chrV 6,497,783	contains similarity to Pfam domain PF03982 Diacylglycerol acyltransferase contains similarity to Interpro domain IPR007130 (Diacylglycerol acyltransferase)
10	fbxb-21	ZC204.8	n/a	chrII 1,648,389	fbxb-21 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-21 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
11	Y51B9A.8	Y51B9A.8	n/a	chrII 9,399,270	contains similarity to Pfam domains PF04942 (CC domain) (2), PF01549 (ShK domain-like) contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
12	sri-70	Y61B8B.1	n/a	chrV 17,303,714	C. elegans SRI-70 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000883 (Cytochrome c oxidase, subunit I)
13	F26D11.6	F26D11.6	n/a	chrV 7,955,880
14	B0304.2	B0304.2	n/a	chrII 4,524,073
15	ubc-21	C06E2.3	n/a	chrX 8,870,667	C. elegans UBC-21 protein; contains similarity to Pfam domain PF00179 Ubiquitin-conjugating enzyme contains similarity to Interpro domains IPR000608 (Ubiquitin-conjugating enzyme, E2), IPR009060 (UBA-like), IPR016135 (Ubiquitin-conjugating enzyme/RWD-like), IPR015940 (Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)
16	tag-40	R02C2.3	n/a	chrV 249,183	C. elegans TAG-40 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
17	rnt-1	B0414.2	n/a	chrI 5,782,356	rnt-1 encodes a transcription factor that is the sole C. elegans member of the RUNX family of transcriptional regulators; rnt-1 activity is required for several developmental processes, including regulation of hypodermal seam cell proliferation and proper development of the male tail; RNT-1 can physically interact with SMA-4 and regulates, either directly or indirectly, expression of tlp-1 and cki-1, which encode a C2H2 zinc finger and CDK inhibitor, respectively; RNT-1::GFP reporter fusions are reportedly expressed in the nuclei of hypodermal seam cells, intestinal cells, body wall muscles, and, in males, cells derived from the V5, V6 and T lineages that give rise to the sensory rays.
18	K08F9.1	K08F9.1	n/a	chrV 15,138,399	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
19	srz-79	C09G12.2	n/a	chrIV 3,494,391	C. elegans SRZ-79 protein ;
20	C53D6.6	C53D6.6	n/a	chrIV 9,030,151	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
21	sri-77	D2062.9	n/a	chrII 2,604,314	C. elegans SRI-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	F53H2.1	F53H2.1	n/a	chrV 20,385,929	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR007883 (Protein of unknown function DUF713)
23	F39G3.6	F39G3.6	n/a	chrV 4,712,695	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
24	ZK686.1	ZK686.1	n/a	chrIII 7,773,406	contains similarity to Interpro domain IPR004038 (Ribosomal protein L7Ae/L30e/S12e/Gadd45)
25	fut-4	K12H6.3	n/a	chrII 2,820,961	fut-4 encodes a member of the glycosyltransferase 10 family.
26	ZK1307.9	ZK1307.9	n/a	chrII 9,650,113	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
27	F26A3.1	F26A3.1	n/a	chrI 7,641,050	contains similarity to Interpro domain IPR008262 (Lipase, active site)
28	F53B7.2	F53B7.2	n/a	chrV 10,993,353	F53B7.2 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that F53B7.2 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
29	ast-1	T08H4.3	n/a	chrII 4,131,358	ast-1 encodes a novel ETS-box transcription factor; AST-1 is required for the proper navigation of some interneuron axons to their targets, for differentiation of the ventral cord pioneer neuron AVG, and for pharyngeal morphogenesis; AST-1 is transiently expressed in many head neurons late in their differentiation and axon outgrowth, and in a few pharyngeal cells; AST-1 is at first nuclear, but then relocates to spots in cell bodies and even neuronal processes; hypomorphic ast-1 mutants have axons extending laterally, and crossing over from the right axon tract to the left axon bundle; null ast-1(hd92) mutants are inviable, failing to attach a working pharynx to their cuticle during development and then starving as L1 larvae; behaviorally, hypomorphic ast-1 animals are at least superficially normal, indicating that the ventral nerve cord can tolerate at least some miswiring; AST-1 regulates odr-2 expression, while ast-1 expression is itself regulated by lin-11.
30	K01A2.6	K01A2.6	n/a	chrII 300,268
31	F42E11.3	F42E11.3	n/a	chrX 11,375,032	contains similarity to Streptococcus mutans Conserved hypothetical protein, possible membrane protein.; TR:Q8DV46
32	T27E7.6	T27E7.6	n/a	chrIV 14,541,148	contains similarity to Interpro domains IPR000533 (Tropomyosin), IPR002291 (Phosphorylase kinase, gamma catalytic subunit)
33	srt-45	M162.3	n/a	chrV 19,780,434	C. elegans SRT-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
34	R05F9.7	R05F9.7	n/a	chrII 4,887,230	contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
35	srab-20	T20D4.1	n/a	chrV 3,429,701	C. elegans SRAB-20 protein; contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
36	Y39A3B.1	Y39A3B.1	n/a	chrIII 2,007,600
37	F07G11.3	F07G11.3	n/a	chrV 7,300,103	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
38	fbxb-35	F07E5.2	n/a	chrII 2,052,208	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
39	T16H12.1	T16H12.1	n/a	chrIII 10,084,745	contains similarity to Human papillomavirus type 70 E7 protein.; SW:VE7_HPV70
40	srw-19	T10H4.8	n/a	chrV 15,280,555	C. elegans SRW-19 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
41	W03F9.1	W03F9.1	n/a	chrV 125,395	contains similarity to Pfam domain PF03367 ZPR1 zinc-finger domain contains similarity to Interpro domain IPR004457 (Zinc finger, ZPR1-type)
42	glb-20	R01E6.6	n/a	chrX 13,554,276	glb-20 encodes a globin; glb-20 transcription is higher in L3 and dauers than in young adults; glb-20 has no obvious function in mass RNAi assays.
43	pde-5	C32E12.2	n/a	chrI 5,198,010	C. elegans PDE-5 protein; contains similarity to Pfam domains PF01590 (GAF domain) , PF00233 (3'5'-cyclic nucleotide phosphodiesterase) contains similarity to Interpro domains IPR002073 (3'5'-cyclic nucleotide phosphodiesterase), IPR003018 (GAF), IPR003607 (Metal-dependent phosphohydrolase, HD region)
44	ZC266.2	ZC266.2	n/a	chrV 4,696,862
45	str-44	C42D4.4	n/a	chrIV 7,177,788	C. elegans STR-44 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	C02B4.3	C02B4.3	n/a	chrX 12,659,689	weak similarity with E. coli hemolysin D protein (Swiss Prot accession number P09986)
47	srx-95	F41G3.11	n/a	chrII 6,753,887	C. elegans SRX-95 protein; contains similarity to Interpro domain IPR003915 (Polycystic kidney disease type 2 protein)
48	F15H10.6	F15H10.6	n/a	chrV 10,411,166	contains similarity to Mycoplasma pneumoniae Oligopeptide transport ATP-binding protein oppF.; SW:OPPF_MYCPN
49	C10G11.6	C10G11.6	n/a	chrI 6,291,932
50	set-9	F15E6.1	n/a	chrIV 4,312,255	set-9 encodes a large (1,655-residue) protein with a low-complexity N-terminal region, followed by a PHD-zinc finger and a SET domain; SET-9 has no non-nematode orthologs, but has 96% identity (1616/1679 residues) to its paralog SET-26; SET-9 is required for a normally short lifespan and low spontaneous mutation rate; life extension by set-9(RNAi) requires DAF-16, indicating that SET-9 limits normal lifespan by negatively regulating DAF-16 (either directly or indirectly); otherwise, neither set-9(n4949) nor set-9(RNAi) have any obvious phenotypes.