UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxb-35	F07E5.2	0	chrII 2,052,208	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	mxl-1	T19B10.11	n/a	chrV 11,245,345	mxl-1 encodes a basic helix-loop-helix protein similar to the vertebrate MAX transcriptional regulators; in vitro, MXL-1 can heterodimerize, and bind an E-box DNA sequence, with MDL-1, a C. elegans MAD-like bHLH protein; mxl-1::gfp reporter fusions are expressed in the posterior intestine and in head and tail neurons.
4	C41G6.13	C41G6.13	n/a	chrV 15,208,853	contains similarity to Homo sapiens Xylosyltransferase I; ENSEMBL:ENSP00000261381
5	C16A3.6	C16A3.6	n/a	chrIII 6,379,994	contains similarity to Pfam domain PF04874 Mak16 protein contains similarity to Interpro domain IPR006958 (Mak16 protein)
6	clec-223	C03E10.5	n/a	chrV 11,275,618	C. elegans CLEC-223 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR008160 (Collagen triple helix repeat)
7	EEED8.13	EEED8.13	n/a	chrII 5,411,874	contains similarity to Interpro domain IPR011038 (Calycin-like)
8	T19H5.1	T19H5.1	n/a	chrII 9,473,432	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
9	ZK686.1	ZK686.1	n/a	chrIII 7,773,406	contains similarity to Interpro domain IPR004038 (Ribosomal protein L7Ae/L30e/S12e/Gadd45)
10	M116.1	M116.1	n/a	chrIV 8,411,585
11	C49C8.3	C49C8.3	n/a	chrIV 8,644,987
12	srab-20	T20D4.1	n/a	chrV 3,429,701	C. elegans SRAB-20 protein; contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
13	clec-12	T27F6.2	n/a	chrI 12,477,625	C. elegans CLEC-12 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
14	hop-1	C18E3.8	n/a	chrI 4,209,468	hop-1 encodes one of three C. elegans presenilins (the other two presenilins are encoded by sel-12 and spe-4); originally identified on the basis of its sequence similarity to SEL-12 and the human PS1 and PS2 presenilins, HOP-1 has been shown to function redundantly with SEL-12 in embryonic, larval, and germline development and thus, to likely function by regulating LIN-12/GLP-1 signaling; in addition, hop-1 can functionally substitute for sel-12 by rescuing the egg-laying and vulval development defects of sel-12 mutants; hop-1 transcription appears to be regulated, at least in part, by the C. elegans spr genes, some of which encode orthologs of the mammalian CoREST repressor complex.
15	F20C5.3	F20C5.3	n/a	chrIV 8,754,081	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
16	nhr-192	F57A8.5	n/a	chrV 10,069,976	C. elegans NHR-192 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
17	C24H10.4	C24H10.4	n/a	chrX 5,058,527
18	F36G9.3	F36G9.3	n/a	chrV 15,958,350	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF05978 (Eukaryotic protein of unknown function (DUF895)) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
19	F53H2.1	F53H2.1	n/a	chrV 20,385,929	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR007883 (Protein of unknown function DUF713)
20	F28C6.2	F28C6.2	n/a	chrII 8,595,158	F28C6.2 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.1, which lies adjacent to F28C6.1 on chromosome II; loss of F28C6.2 activity via large-scale RNAi results in some embryonic lethality and low levels of larval arrest, body morphology defects, and uncoordinated locomotion.
21	gcy-13	F23H12.6	n/a	chrV 12,366,622	gcy-13 encodes a predicted guanylate cyclase.
22	srw-98	K04F1.3	n/a	chrV 1,677,402	C. elegans SRW-98 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
23	K02A2.1	K02A2.1	n/a	chrII 7,435,459	contains similarity to Pfam domain PF01738 Dienelactone hydrolase family contains similarity to Interpro domain IPR002925 (Dienelactone hydrolase)
24	T19H5.4	T19H5.4	n/a	chrII 9,487,245	contains similarity to Gallus gallus Homeobox prospero-like protein PROX1 (PROX 1).; SW:PRX1_CHICK
25	lgg-3	B0336.8	n/a	chrIII 5,697,730	lgg-3 encodes a hydrophilic protein that is orthologous to Saccharomyces cerevisiae autophagy protein Apg12p; by homology, LGG-3 is predicted to function as a modifier protein required for a protein conjugation system essential for autophagy; in the context of this conjugation system, LGG-3 is predicted to interact with Apg7p and Apg5p homologs (encoded by M7.5 and Y71G12B.12a, respectively) to effect bulk degradation of cytoplasmic components under conditions of starvation or cellular remodeling; free LGG-3 is predicted to localize to the cytoplasm, while LGG-3 conjugated to the Apg5p homolog is predicted to associate with membrane compartments; loss of lgg-3 activity via large-scale RNAi screens results in no obvious developmental or behavioral abnormalities.
26	srx-95	F41G3.11	n/a	chrII 6,753,887	C. elegans SRX-95 protein; contains similarity to Interpro domain IPR003915 (Polycystic kidney disease type 2 protein)
27	2L52.1	2L52.1	n/a	chrII 3,265	2L52.1 encodes a protein with sequence similarity to GLI-family zinc-finger transcription factors; deletion mutations in 2L52.1 are reported to be homozygous viable.
28	lgc-9	C04C3.2	n/a	chrIV 3,417,455	C. elegans LGC-9 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
29	Y49A10A.1	Y49A10A.1	n/a	chrX 10,359,445	contains similarity to Pfam domain PF06565 Repeat of unknown function (DUF1126) contains similarity to Interpro domains IPR010554 (Protein of unknown function DUF1126), IPR006602 (Region of unknown function DM10)
30	K01A2.6	K01A2.6	n/a	chrII 300,268
31	F14D2.8	F14D2.8	n/a	chrII 3,348,717	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
32	hlh-12	C28C12.8	n/a	chrIV 8,478,993	C. elegans HLH-12 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding), IPR002418 (Transcription regulator Myc)
33	F56H6.4	F56H6.4	n/a	chrI 12,291,320	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
34	W06D11.1	W06D11.1	n/a	chrX 12,294,462
35	F35H10.5	F35H10.5	n/a	chrIV 8,300,920
36	H25K10.6	H25K10.6	n/a	chrIV 16,235,400	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
37	ZC155.4	ZC155.4	n/a	chrIII 5,213,465	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
38	tbx-36	ZK829.5	n/a	chrIV 11,951,305	C. elegans TBX-36 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
39	C16C4.1	C16C4.1	n/a	chrII 1,894,512
40	str-227	C07G3.3	n/a	chrV 3,518,993	C. elegans STR-227 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	F54F7.6	F54F7.6	n/a	chrX 11,866,107	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
42	C53B4.6	C53B4.6	n/a	chrIV 8,985,786	contains similarity to Pfam domain PF08449 UAA transporter family contains similarity to Interpro domain IPR013657 (UAA transporter)
43	W02D7.5	W02D7.5	n/a	chrV 8,298,506	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
44	ZK1240.4	ZK1240.4	n/a	chrII 2,315,354
45	T01E8.4	T01E8.4	n/a	chrII 10,238,236	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains WD repeats.
46	clec-127	W10G11.5	n/a	chrII 3,568,702	C. elegans CLEC-127 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
47	T13F2.6	T13F2.6	n/a	chrIV 9,779,719
48	F20D1.7	F20D1.7	n/a	chrX 14,989,294	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR007110 (Immunoglobulin-like)
49	R11H6.4	R11H6.4	n/a	chrV 14,610,325	contains similarity to Homo sapiens Steerin3 protein; ENSEMBL:ENSP00000228327
50	F53B7.4	F53B7.4	n/a	chrV 11,001,724	contains similarity to Interpro domains IPR004090 (Chemotaxis methyl-accepting receptor), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)