UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F57B10.5	F57B10.5	1.9999999999999999e-115	chrI 6,563,176	contains similarity to Pfam domain PF01105 emp24/gp25L/p24 family/GOLD contains similarity to Interpro domains IPR009038 (GOLD), IPR000348 (emp24/gp25L/p24)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	Y47D3B.1	Y47D3B.1	n/a	chrIII 11,385,678	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008166 (Protein of unknown function DUF23), IPR000276 (GPCR, rhodopsin-like)
4	F38B2.3	F38B2.3	n/a	chrX 11,283,730	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
5	F46C8.1	F46C8.1	n/a	chrX 7,550,722
6	R04B3.2	R04B3.2	n/a	chrX 2,472,601	The R04B3.2 gene encodes an ortholog of the human gene LYSOSOMAL GLYCOSYLASPARAGINASE (AGA; OMIM:208400), which when mutated leads to aspartylglucosaminuria (OMIM:208400).
7	ttb-1	W03F9.5	n/a	chrV 160,090	C. elegans TTB-1 protein; contains similarity to Pfam domains PF00382 (Transcription factor TFIIB repeat) (2), PF08271 (TFIIB zinc-binding) contains similarity to Interpro domains IPR006670 (Cyclin), IPR000812 (Transcription factor TFIIB related), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR013150 (Transcription factor TFIIB, cyclin-related), IPR013137 (Zinc finger, TFIIB-type)
8	Y57G11C.31	Y57G11C.31	n/a	chrIV 14,685,186	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
9	ZK1225.1	ZK1225.1	n/a	chrI 13,206,699	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
10	M04F3.4	M04F3.4	n/a	chrI 4,772,433	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
11	W03F11.5	W03F11.5	n/a	chrI 2,217,759	n/a
12	cdc-42	R07G3.1	n/a	chrII 7,617,275	cdc-42 encodes a RHO GTPase which controls polarity of both individual cells and developing embryos by regulating the localization of PAR proteins; CDC-42 is expressed at hypodermal cell boundaries; cdc-42 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults.
13	flr-1	F02D10.5	n/a	chrX 13,454,529	flr-1 encodes an ion channel that belongs to the DEG/ENaC sodium channel superfamily; flr-1 activity is essential for normal defecation rhythm, growth rates, expulsion, and dauer larvae formation; a rescuing FLR-1::GFP reporter is expressed in the intestine from embryonic to adult stages where it localizes to the membranes facing the inner lumen as well as to part of the lateral membrane between intestinal cells.
14	C34E7.4	C34E7.4	n/a	chrX 12,933,527	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
15	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
16	F01G10.9	F01G10.9	n/a	chrIV 10,257,677	contains similarity to Interpro domain IPR000694 (Proline-rich region)
17	tag-123	F08F1.7	n/a	chrX 8,420,290	C. elegans TAG-123 protein; contains similarity to Pfam domain PF02990 Endomembrane protein 70 contains similarity to Interpro domains IPR008075 (Lipocalin-1 receptor), IPR004240 (Nonaspanin (TM9SF))
18	F11A5.6	F11A5.6	n/a	chrV 16,203,986	contains similarity to Bradyrhizobium japonicum Bll7368 protein.; TR:Q89DS1
19	R05D7.5	R05D7.5	n/a	chrI 12,186,205	contains similarity to Ascaris suum P40.; TR:Q7YXJ9
20	C14B9.3	C14B9.3	n/a	chrIII 8,109,908
21	F53G12.3	F53G12.3	n/a	chrI 141,205	F53G12.3 encodes a large partial homolog of dual oxidase ('Ce-Duox2'), with an N-terminal peroxidase domain, two central calmodulin-binding EF hands, and a C-terminal superoxide-generating NADPH-oxidase domain; F53G12.3 may be required for dityrosine cross-linking of collagen, and thus for cuticular integrity; F53G12.3 may use cytosolic NADPH to generate reactive oxygen, which then may drive the peroxidase ectodomain to cross-link free tyrosine in collagen; F53G12.3 has no visible expression pattern detectable by antibodies, implying very low or rare expression.
22	math-21	C40D2.3	n/a	chrII 1,994,852	C. elegans MATH-21 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
23	C13C12.2	C13C12.2	n/a	chrV 12,524,627	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
24	R09D1.8	R09D1.8	n/a	chrII 9,460,970	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
25	F53E10.1	F53E10.1	n/a	chrV 2,617,140	contains similarity to Pfam domains PF03473 (MOSC domain) , PF03476 (MOSC N-terminal beta barrel domain) contains similarity to Interpro domains IPR005303 (MOSC, N-terminal beta barrel), IPR005302 (Molybdenum cofactor sulphurase, C-terminal), IPR011037 (Pyruvate kinase, beta-barrel-like)
26	ZC513.2	ZC513.2	n/a	chrV 8,055,592	contains similarity to Pfam domain PF01273 LBP / BPI / CETP family, N-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
27	col-73	F11G11.12	n/a	chrII 4,872,607	C. elegans COL-73 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR000596 (Cholecystokinin receptor, type A), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
28	pqn-59	R119.4	n/a	chrI 377,739	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
29	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
30	pqn-67	T16G1.1	n/a	chrV 12,926,198	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
31	T15D6.4	T15D6.4	n/a	chrI 12,375,417	contains similarity to Aedes aegypti N-acetyllactosaminide beta-1,3-n-acetylglucosaminyltransferase.; TR:Q175J5
32	ltd-1	K02C4.4	n/a	chrII 8,090,520	ltd-1 encodes a protein with LIM and transglutaminase domains; LTD-1 is homologous to the mouse KY protein (MGI:96709, mutated in kyphoscoliosis), and to the HILLARIN protein of Hirudo medicinalis, found at axon hillocks; ltd-1 is expressed in hypodermal cells from the twofold stage embryo to adulthood, but has no obvious function in mass RNAi assays.
33	tra-3	LLC1.1	n/a	chrIV 14,440,241	tra-3 encodes an atypical calpain regulatory protease that lacks calcium-binding EF hand domains; during development, TRA-3 likely promotes female development in XX hermaphrodites by cleaving the membrane-associated TRA-2A protein to generate a TRA-2 peptide likely to have feminizing activity; in addition, TRA-3 is one of several proteases that mediate necrotic cell death during neurodegeneration.
34	ZC328.2	ZC328.2	n/a	chrI 6,389,348	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
35	K07C11.4	K07C11.4	n/a	chrV 8,204,685	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
36	C24H10.2	C24H10.2	n/a	chrX 5,065,438
37	F58G1.6	F58G1.6	n/a	chrII 12,941,277	contains similarity to Pfam domain PF02752 Arrestin (or S-antigen), C-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal)
38	F40E3.2	F40E3.2	n/a	chrI 2,643,222
39	T22B11.2	T22B11.2	n/a	chrIV 4,690,180	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
40	ZC513.1	ZC513.1	n/a	chrV 8,056,969	contains similarity to Pfam domain PF02886 LBP / BPI / CETP family, C-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
41	F52G3.5	F52G3.5	n/a	chrX 16,974,629	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR003582 (Metridin-like ShK toxin)
42	ZK185.2	ZK185.2	n/a	chrIV 4,539,155	ZK185.2 encodes an ortholog of human SLC41A1 (OMIM:610801) and bacterial MgtE; like its orthologs, ZK185.2 is predicted to transport Mg(2+) into cells; ZK185.2 is paralogous to K07H8.2 and ZK1053.6, and has no obvious function in mass RNAi assays.
43	crb-1	F11C7.4	n/a	chrX 17,408,117	crb-1 encodes a homolog of Drosophila CRUMBS that affects dauer formation and feeding behavior; CRB-1 can bind cyclic AMP-response element (CRE) sites and be phosphorylated by PKA in vitro, and is expressed immediately apical to the zonula adherens in embryos and then ubiquitously later during development and in adults; CRB-1 is homologous to human CRB1 (OMIM:604210, mutated in retinitis pigmentosa 12 or Leber congenital amaurosis).
44	T01B10.5	T01B10.5	n/a	chrX 8,496,580
45	tra-4	F53B3.1	n/a	chrX 2,855,643	C. elegans TRA-4 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR008162 (Inorganic pyrophosphatase), IPR015880 (Zinc finger, C2H2-like), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
46	tsr-1	F53G2.6	n/a	chrII 2,466,865	tsr-1 encodes a homolog of human transportin-SR, a nuclear transport receptor, and affects embryonic viability.
47	F08D12.7	F08D12.7	n/a	chrII 2,768,193	F08D12.7 encodes a novel protein conserved amongst Caenorhaditis species; although loss of F08D12.7 activity via RNAi results in no obvious defects, F08D12.7 transcripts are enriched in L1-stage muscle and upregulated in L2 larvae in response to overexpression of hlh-2 and hlh-8; in addition, in analyses of the early embryonic transcriptome, F08D12.7 transcripts are classified as strictly maternal; an F08D12.7::gfp reporter fusion is expressed in the vm1 and vm2 vulval muscles, the intestinal and anal depressor muscles, the hypodermis, distal tip cell, ventral nerve cord, head and tail neurons, and body wall muscle.
48	C18H7.5	C18H7.5	n/a	chrIV 587,001
49	ZK154.5	ZK154.5	n/a	chrX 7,785,505	contains similarity to Homo sapiens Isoform 4 of Target of Nesh-SH3 precursor; ENSEMBL:ENSP00000373190
50	sem-5	C14F5.5	n/a	chrX 7,960,532	sem-5 encodes a Src homology (SH) domain 2 and 3-containing protein, orthologous to human GRB2 (OMIM:108355), that functions in multiple signaling pathways during development; these pathways include those regulating sex myoblast migration, muscle membrane extension, vulval induction, fluid balance, viability, and formation of the male tail; SEM-5 acts downstream of the LET-23 epidermal growth factor receptor to negatively regulate RAS-, MAP-, as well as IP-3-, mediated signal transduction.