UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	K02E2.7	K02E2.7	5.9999999999999995e-64	chrV 20,380,450	contains similarity to Homo sapiens RB1-inducible coiled-coil protein 1; ENSEMBL:ENSP00000025008
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	flp-10	T06C10.4	n/a	chrIV 7,869,261	flp-10 encodes a FMRFamide-related neuropeptide; in males, flp-10 activity is required for a sensory transduction pathway that negatively regulates the frequency of certain substeps of turning behavior during mating; a flp-10::gfp reporter is expressed in a number of neurons including AIM, ASI, AUA, BAG, BDU, DVB, PQR, PVR, and URX, and in the vulD cells.
4	lov-1	ZK945.9	n/a	chrII 10,115,543	lov-1 encodes an ortholog of human PKD1 (OMIM:601313; mutated in autosomal dominant polycystic kidney disease) that is expressed in the ciliated sensory endings of three types of male-specific neurons and that is required for two aspects of male mating behavior: response to hermaphrodite contact and vulva location; LOV-1 acts with PKD-2; EGL-44 and EGL-46 regulate cell-specific expression of lov-1 and pkd-2 to specify the behavioral function of the HOB neuron; in vitro, LOV-1 interacts, via its conserved PLAT domain, with the N-terminus of ATP-2, the beta subunit of ATP synthase that also localizes to cilia, suggesting that ATP synthase may play a role in C. elegans polycystin signaling.
5	F26A3.1	F26A3.1	n/a	chrI 7,641,050	contains similarity to Interpro domain IPR008262 (Lipase, active site)
6	C18D4.4	C18D4.4	n/a	chrV 17,530,973	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
7	C02F12.5	C02F12.5	n/a	chrX 3,671,203	C02F12.5 encodes a putatively secreted protein with a Kunitz/bovine pancreatic trypsin inhibitor domain; C02F12.5 has no obvious function in mass RNAi assays.
8	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
9	F21C10.4	F21C10.4	n/a	chrV 9,127,111	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
10	Y51B9A.8	Y51B9A.8	n/a	chrII 9,399,270	contains similarity to Pfam domains PF04942 (CC domain) (2), PF01549 (ShK domain-like) contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR003582 (Metridin-like ShK toxin)
11	twk-2	T12C9.3	n/a	chrII 4,447,199	twk-2 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-2 in C. elegans development and/or behavior is not yet known, but TWK-2 may function redundantly with other TWK channels; TWK-2 is expressed in a subset of neurons.
12	srab-17	T11A5.2	n/a	chrV 9,867,491	C. elegans SRAB-17 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
13	T27E7.6	T27E7.6	n/a	chrIV 14,541,148	contains similarity to Interpro domains IPR000533 (Tropomyosin), IPR002291 (Phosphorylase kinase, gamma catalytic subunit)
14	srx-20	R13H7.1	n/a	chrIV 6,868,598	C. elegans SRX-20 protein ;
15	Y106G6E.4	Y106G6E.4	n/a	chrI 10,222,213	contains similarity to Pfam domain PF01812 5-formyltetrahydrofolate cyclo-ligase family contains similarity to Interpro domain IPR002698 (5-formyltetrahydrofolate cyclo-ligase)
16	pde-5	C32E12.2	n/a	chrI 5,198,010	C. elegans PDE-5 protein; contains similarity to Pfam domains PF01590 (GAF domain) , PF00233 (3'5'-cyclic nucleotide phosphodiesterase) contains similarity to Interpro domains IPR002073 (3'5'-cyclic nucleotide phosphodiesterase), IPR003018 (GAF), IPR003607 (Metal-dependent phosphohydrolase, HD region)
17	tag-40	R02C2.3	n/a	chrV 249,183	C. elegans TAG-40 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
18	nhr-140	C33G8.9	n/a	chrV 6,988,762	C. elegans NHR-140 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	str-102	R08H2.13	n/a	chrV 15,385,819	C. elegans STR-102 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	T15D6.8	T15D6.8	n/a	chrI 12,390,358	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
21	try-2	C07G1.1	n/a	chrIV 8,213,133	try-2 encodes a homolog of human TRYP1 and ELA2; mutation of human TRYP1 or ELA2 leads, respectively, to hereditary pancreatitis (OMIM:276000) or cyclic haematopoiesis (OMIM:162800).
22	K07A9.3	K07A9.3	n/a	chrIV 1,835,383	contains similarity to Interpro domain IPR001736 (Phospholipase D/Transphosphatidylase)
23	Y6E2A.5	Y6E2A.5	n/a	chrV 15,717,512	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domain IPR007883 (Protein of unknown function DUF713)
24	xtr-1	F54F7.4	n/a	chrX 11,852,038	xtr-1 encodes a protein with similarity to TRA-2A and TRA-2B in a region known as the MX region, hypothesized to be a protein-protein interaction domain involved in negatively regulating tra-2 activity in the germ line.
25	C54A12.2	C54A12.2	n/a	chrII 5,254,604	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR000276 (GPCR, rhodopsin-like)
26	str-138	ZC513.11	n/a	chrV 8,059,468	C. elegans STR-138 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	ZK1307.9	ZK1307.9	n/a	chrII 9,650,113	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
28	fbxa-2	T13F3.5	n/a	chrV 16,268,911	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
29	K08H2.7	K08H2.7	n/a	chrX 13,247,766	contains similarity to Synechocystis sp Probable glycogen synthase 2 (EC 2.4.1.21) (Starch [bacterialsglycogen] synthase 2).; SW:GLG2_SYNY3
30	T22F7.4	T22F7.4	n/a	chrIII 526,147
31	clec-15	T07D10.4	n/a	chrI 12,631,859	C. elegans CLEC-15 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
32	Y38H6C.19	Y38H6C.19	n/a	chrV 20,548,064	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
33	C17H1.2	C17H1.2	n/a	chrI 13,102,913	contains similarity to Apple stem grooving virus Genome polyprotein [Contains: RNA replicase (EC 2.7.7.48); Helicase;sCoat protein].; SW:POLR_ASGVP
34	acbp-5	T12D8.3	n/a	chrIII 13,640,695	C. elegans ACBP-5 protein; contains similarity to Pfam domains PF00023 (Ankyrin repeat) (2), PF00887 (Acyl CoA binding protein) contains similarity to Interpro domains IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR002110 (Ankyrin), IPR000582 (Acyl-CoA-binding protein, ACBP)
35	W08F4.5	W08F4.5	n/a	chrII 567,279
36	tag-225	K07C11.5	n/a	chrV 8,202,146	K07C11.5 is orthologous to the human gene SIMILAR TO TISSUE INHIBITOR OF METALLOPROTEINASE 3 (SORSBY FUNDUS DYSTROPHY, PSEUDOINFLAMMATORY) (TIMP3; OMIM:188826), which when mutated leads to disease.
37	C54F6.4	C54F6.4	n/a	chrV 7,530,843	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domain IPR004316 (MtN3 and saliva related transmembrane protein)
38	F57B1.5	F57B1.5	n/a	chrV 13,208,243	contains similarity to unidentified bacterium Hypothetical protein.; TR:Q93DU5
39	F15H10.6	F15H10.6	n/a	chrV 10,411,166	contains similarity to Mycoplasma pneumoniae Oligopeptide transport ATP-binding protein oppF.; SW:OPPF_MYCPN
40	skr-16	C42D4.6	n/a	chrIV 7,169,011	The skr-16 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-16(RNAi) animals are at least superficially normal.
41	Y11D7A.10	Y11D7A.10	n/a	chrIV 9,259,330	contains similarity to Coniophora arida ATP synthase subunit 6 (EC 3.6.3.14) (ATP synthase A chain)s(Fragment).; TR:Q9XLN6
42	F46G11.2	F46G11.2	n/a	chrX 5,789,196
43	W03G1.4	W03G1.4	n/a	chrIV 509,467	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
44	C06E4.6	C06E4.6	n/a	chrIV 7,257,716	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
45	ZK930.2	ZK930.2	n/a	chrII 11,892,790	contains similarity to Interpro domain IPR010989 (t-SNARE)
46	Y7A5A.9	Y7A5A.9	n/a	chrX 15,828,129	contains similarity to Cyprinus carpio Nucleolin.; TR:Q804J2
47	Y42A5A.3	Y42A5A.3	n/a	chrV 11,095,685	contains similarity to Bacillus subtilis Hypothetical protein yhen.; TR:O07596
48	C13A10.1	C13A10.1	n/a	chrII 1,353,185
49	F14H3.12	F14H3.12	n/a	chrV 16,074,705	contains similarity to Pfam domain PF02149 Kinase associated domain 1 contains similarity to Interpro domain IPR001772 (Kinase-associated KA1)
50	cyp-13A7	T10B9.10	n/a	chrII 9,804,455	cyp-13A7 encodes a homolog of cytochrome P450 proteins; these proteins are membrane proteins with a heme prosthetic group that catalyse the synthesis of steroid hormones (and bile salts), and also detoxify foreign substances (xenobiotic compounds).