UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	grl-3	K03B8.7	3e-152	chrV 11,411,850	grl-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-3 is expressed in intestine, larval renal gland cells, and larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
2	clec-249	Y51A2A.7	n/a	chrV 18,304,784	C. elegans CLEC-249 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
3	F15D4.2	F15D4.2	n/a	chrII 13,216,307	contains similarity to Strongylocentrotus purpuratus Protein ENDO16 (Fragment).; SW:P13665
4	spp-6	T08A9.10	n/a	chrX 7,317,449	spp-6 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-6 is predicted to function as a lipid-binding protein that may possess pore-forming, cytotoxic activity; as loss of SPP-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of SPP-6 in C. elegans development and/or behavior is not yet known.
5	F57E7.2	F57E7.2	n/a	chrV 16,482,980	contains similarity to Psilotum nudum Hypothetical protein.; TR:Q8WHW9
6	Y40H7A.11	Y40H7A.11	n/a	chrIV 15,219,977	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
7	Y38H6C.21	Y38H6C.21	n/a	chrV 20,550,079	contains similarity to Aquifex aeolicus Flagellar biosynthetic protein flhB.; SW:FLHB_AQUAE
8	K08D9.6	K08D9.6	n/a	chrV 3,233,173	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
9	Y106G6D.6	Y106G6D.6	n/a	chrI 10,120,080	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
10	ZK930.2	ZK930.2	n/a	chrII 11,892,790	contains similarity to Interpro domain IPR010989 (t-SNARE)
11	str-171	T01G5.5	n/a	chrV 15,131,482	C. elegans STR-171 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	C40C9.4	C40C9.4	n/a	chrX 13,651,413	contains similarity to Saccharomyces cerevisiae Protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; SGD:YML034W
13	C01G6.4	C01G6.4	n/a	chrII 9,272,092	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
14	C13A2.11	C13A2.11	n/a	chrV 7,281,405	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
15	T26H5.8	T26H5.8	n/a	chrV 15,429,911	contains similarity to Pfam domains PF04789 (Protein of unknown function (DUF621)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR006874 (Protein of unknown function DUF621)
16	F26G1.3	F26G1.3	n/a	chrII 4,759,013	F26G1.3 encodes a protein containing a transthyretin-like domain; the product of F26G1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
17	C43F9.4	C43F9.4	n/a	chrIV 10,588,322
18	D1079.1	D1079.1	n/a	chrX 4,405,551
19	col-37	ZK863.2	n/a	chrV 12,167,206	col-37 encodes a cuticle collagen.
20	F27E5.1	F27E5.1	n/a	chrII 10,140,416	contains similarity to Pfam domain PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family contains similarity to Interpro domains IPR003199 (Choloylglycine hydrolase), IPR016699 (Acid ceramidase-like)
21	try-2	C07G1.1	n/a	chrIV 8,213,133	try-2 encodes a homolog of human TRYP1 and ELA2; mutation of human TRYP1 or ELA2 leads, respectively, to hereditary pancreatitis (OMIM:276000) or cyclic haematopoiesis (OMIM:162800).
22	F17E9.2	F17E9.2	n/a	chrIV 8,356,187
23	C08B6.5	C08B6.5	n/a	chrV 10,118,697	contains similarity to Danio rerio Glutamate receptor delta-2 subunit precursor (GluR delta-2).; SW:Q68Y21
24	W07B8.4	W07B8.4	n/a	chrV 1,131,011	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
25	F48A9.2	F48A9.2	n/a	chrI 6,593,082
26	C33A12.7	C33A12.7	n/a	chrIV 9,507,832	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
27	R03H4.5	R03H4.5	n/a	chrV 9,020,799	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
28	his-8	F45F2.12	n/a	chrV 8,532,878	his-8 encodes an H2B histone; his-8 is contained within the histone gene cluster HIS2.
29	hex-1	T14F9.3	n/a	chrX 2,225,047	hex-1 encodes a beta-N-acetylhexosaminidase that is orthologous to the human gene CERVICAL CANCER PROTO-ONCOGENE 7 (HEXB; OMIM:606873), which when mutated leads to disease.
30	C31B8.4	C31B8.4	n/a	chrV 2,897,526	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
31	K01H12.1	K01H12.1	n/a	chrIV 9,707,386	K01H12.1 encodes a small protein conserved in diverse eukaryotes, with a CSL motif (a probable zinc finger, sometimes found associated with the N-terminal domain of DnaJ protein); K01H12.1 is probably a small subunit or ancillary protein of RNA polymerase II Elongator or of a hypothetical diphthamide synthase complex; K01H12.1 is orthologous to to mammalian DESR1 (diphtheria toxin and Pseudomonas exotoxin A sensitivity required gene 1) and S. cerevisiae KTI11; DESR1, and probably KTI11, enables the first step in posttranslational modification of histidine to dipthamide; K01H12.1 has no obvious function in mass RNAi assays.
32	K08D8.1	K08D8.1	n/a	chrIV 12,893,458	contains similarity to Fusobacterium nucleatum Tryptophanase (EC 4.1.99.1).; TR:Q8RHQ6
33	ttr-37	F21E9.3	n/a	chrX 1,336,135	C. elegans TTR-37 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
34	T23F4.3	T23F4.3	n/a	chrII 1,170,980	contains similarity to Pfam domain PF01738 Dienelactone hydrolase family contains similarity to Interpro domain IPR002925 (Dienelactone hydrolase)
35	sri-2	F36G9.9	n/a	chrV 15,964,503	C. elegans SRI-2 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002208 (SecY protein)
36	flp-10	T06C10.4	n/a	chrIV 7,869,261	flp-10 encodes a FMRFamide-related neuropeptide; in males, flp-10 activity is required for a sensory transduction pathway that negatively regulates the frequency of certain substeps of turning behavior during mating; a flp-10::gfp reporter is expressed in a number of neurons including AIM, ASI, AUA, BAG, BDU, DVB, PQR, PVR, and URX, and in the vulD cells.
37	ref-1	T01E8.2	n/a	chrII 10,219,169	ref-1 encodes a protein with two basic helix-loop-helix (bHLH) domains that is distantly related to the hairy/Enhancer of split subfamily of bHLH transcription factors; REF-1 is required in hermaphrodites during early larval development for regulating the pattern of posterior Pn.p hypodermal cell fusions, primarily through regulation of MAB-5 homeodomain protein activity; REF-1 is also required for head morphogenesis and specification of the V6 lateral seam cell fate; in males, ref-1 is a target of MAB-3 transcriptional repression which in turn, promotes expression of LIN-32, a proneural bHLH transcription factor.
38	R03H10.1	R03H10.1	n/a	chrII 4,181,882	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
39	ZC196.1	ZC196.1	n/a	chrV 8,744,495
40	F14H3.12	F14H3.12	n/a	chrV 16,074,705	contains similarity to Pfam domain PF02149 Kinase associated domain 1 contains similarity to Interpro domain IPR001772 (Kinase-associated KA1)
41	H43I07.1	H43I07.1	n/a	chrV 4,206,564	contains similarity to Interpro domains IPR010754 (Optic atrophy 3-like), IPR005819 (Histone H5)
42	srx-128	F55B12.7	n/a	chrV 13,838,056	C. elegans SRX-128 protein ;
43	tag-40	R02C2.3	n/a	chrV 249,183	C. elegans TAG-40 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
44	W04D12.1	W04D12.1	n/a	chrIII 5,837,006
45	F26A3.1	F26A3.1	n/a	chrI 7,641,050	contains similarity to Interpro domain IPR008262 (Lipase, active site)
46	Y57G11C.18	Y57G11C.18	n/a	chrIV 14,841,760	contains similarity to Interpro domain IPR000767 (Disease resistance protein)
47	clec-5	C35D10.14	n/a	chrIII 4,882,708	C. elegans CLEC-5 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR013838 (Beta tubulin, autoregulation binding site), IPR001304 (C-type lectin)
48	K09D9.9	K09D9.9	n/a	chrV 3,993,382
49	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
50	nhr-188	F47C10.7	n/a	chrV 3,857,080	C. elegans NHR-188 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)