UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	his-3	T10C6.12	9.999999999999999e-43	chrV 16,040,965	his-3 encodes an H2A histone; by homology, HIS-3 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-3 is a replication-dependent histone locus that resides in the HIS1 cluster on chromosome V.
2	gly-13	B0416.6	n/a	chrX 9,295,081	gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates; gly-13 is expressed throughout development in many cell types; gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14.
3	H23N18.4	H23N18.4	n/a	chrV 4,902,178	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
4	R12E2.12	R12E2.12	n/a	chrI 4,174,271	contains similarity to Interpro domain IPR000529 (Ribosomal protein S6)
5	Y56A3A.19	Y56A3A.19	n/a	chrIII 11,915,313	contains similarity to Pfam domain PF00550 Phosphopantetheine attachment site contains similarity to Interpro domains IPR006163 (Phosphopantetheine-binding), IPR009081 (Acyl carrier protein-like), IPR003231 (Acyl carrier protein (ACP))
6	F25E5.1	F25E5.1	n/a	chrV 7,468,526	contains similarity to Interpro domain IPR009091 (Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)
7	C33D3.3	C33D3.3	n/a	chrX 10,485,911	contains similarity to Interpro domains IPR000679 (Zinc finger, GATA-type), IPR013088 (Zinc finger, NHR/GATA-type), IPR011011 (Zinc finger, FYVE/PHD-type)
8	prx-19	F54F2.8	n/a	chrIII 8,808,467	prx-19 is orthologous to the human gene PEROXISOMAL FARNESYLATED PROTEIN (PXF; OMIM:600279), which when mutated leads to peroxisome biogenesis (Zellweger) syndrome of complementation group J.
9	pcp-2	F23B2.12	n/a	chrIV 9,162,862	C. elegans PCP-2 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domains IPR008758 (Peptidase S28), IPR000258 (Bacterial ice-nucleation proteins octamer repeat)
10	rap-3	C08F8.7	n/a	chrIV 11,177,654	C. elegans RAP-3 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily)
11	F15D4.5	F15D4.5	n/a	chrII 13,246,445	contains similarity to Interpro domain IPR001878 (Zinc finger, CCHC-type)
12	ppk-3	VF11C1L.1	n/a	chrX 12,972,222	C. elegans PPK-3 protein; contains similarity to Pfam domains PF01504 (Phosphatidylinositol-4-phosphate 5-Kinase) , PF01363 (FYVE zinc finger) contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002498 (Phosphatidylinositol-4-phosphate 5-kinase, core), IPR016034 (Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup), IPR002423 (Chaperonin Cpn60/TCP-1), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
13	F08A8.3	F08A8.3	n/a	chrI 12,948,957	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
14	T11G6.4	T11G6.4	n/a	chrIV 10,850,812	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
15	F55E10.6	F55E10.6	n/a	chrX 8,345,470	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
16	elt-2	C33D3.1	n/a	chrX 10,482,266	elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation
17	H19N07.1	H19N07.1	n/a	chrV 11,111,736	contains similarity to Pfam domains PF03143 (Elongation factor Tu C-terminal domain) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) contains similarity to Interpro domains IPR000795 (Protein synthesis factor, GTP-binding), IPR004160 (Translation elongation factor EFTu/EF1A, C-terminal), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR009001 (Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)
18	F26H9.5	F26H9.5	n/a	chrI 9,313,557	contains similarity to Pfam domain PF00266 Aminotransferase class-V contains similarity to Interpro domains IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR000192 (Aminotransferase, class V/Cysteine desulphurase), IPR003248 (Phosphoserine aminotransferase), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
19	dnc-2	C28H8.12	n/a	chrIII 5,925,025	dnc-2 encodes a member of the dynamitin family that affects spindle alignment in polarized cells in early embryos, nuclear movement, spindle morphology, chromosome segregation, and pronuclear migration.
20	F43E2.9	F43E2.9	n/a	chrII 7,359,080
21	F39B2.3	F39B2.3	n/a	chrI 14,788,812	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
22	M02G9.1	M02G9.1	n/a	chrII 10,330,867	contains similarity to Pfam domain PF02363 Cysteine rich repeat contains similarity to Interpro domains IPR003341 (Cysteine rich repeat, tripleX), IPR015333 (Pollen allergen ole e 6)
23	R04E5.2	R04E5.2	n/a	chrX 8,814,421	R04E5.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, M02F4.3, and R13G10.4; by orthology with MAM3, R04E5.2 may participate in metal homoeostasis; R04E5.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; R04E5.2 has no obvious function in RNAi assays.
24	inx-15	R12E2.9	n/a	chrI 4,160,065	C. elegans INX-15 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
25	Y43F8C.4	Y43F8C.4	n/a	chrV 19,627,836	contains similarity to Homo sapiens 90 kDa protein; VG:OTTHUMP00000182483
26	K11B4.1	K11B4.1	n/a	chrI 14,796,015	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
27	arx-5	Y37D8A.1	n/a	chrIII 12,817,350	arx-5 encodes the C. elegans ortholog of the p21Arc subunit of the actin-related protein (Arp) 2/3 complex.
28	nlt-1	ZK892.2	n/a	chrII 10,000,661	nlt-1 encodes a member of the SCP-2 sterol transfer family.
29	oxi-1	Y39A1C.2	n/a	chrIII 10,862,495	C. elegans OXI-1 protein; contains similarity to Pfam domain PF00632 HECT-domain (ubiquitin-transferase) contains similarity to Interpro domain IPR000569 (HECT)
30	nuo-1	C09H10.3	n/a	chrII 11,099,005	nuo-1 encodes a encodes a 51 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation, resistance to volatile anesthetics, and progression through development; nuo-1 is orthologous to human NDUFV1 (OMIM:161015, mutated in Leigh syndrome); nuo-1(ua1) induces a developmental arrest at the third larval (L3) stage that blocks reproduction, and thus is lethal to a population homozygous for nuo-1(ua1); yet arrested L3 nuo-1(ua1) animals have an individual lifespan significantly longer than normal.
31	tag-197	F08C6.3	n/a	chrX 7,566,676	C. elegans TAG-197 protein; contains similarity to Pfam domain PF04129 Vps52 / Sac2 family contains similarity to Interpro domain IPR007258 (Vps52/Sac2)
32	C11H1.5	C11H1.5	n/a	chrX 14,300,542	contains similarity to Pfam domain PF00090 Thrombospondin type 1 domain contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
33	F53F1.2	F53F1.2	n/a	chrV 13,407,532	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
34	K10D11.6	K10D11.6	n/a	chrIV 12,988,061	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
35	kqt-2	M60.5	n/a	chrX 8,244,691	kqt-2 encodes one of three C. elegans KCNQ-like potassium channel subunits for which mutations in humans are associated with heredity diseases that affect epithelial cells, cardiac muscle and neurons; a KQT-2::GFP fusion protein is expressed exclusively in the intestine.
36	Y54G11A.7	Y54G11A.7	n/a	chrII 14,298,367	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR000023 (Phosphofructokinase)
37	C35A11.4	C35A11.4	n/a	chrV 5,391,300	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
38	C05E11.7	C05E11.7	n/a	chrX 4,583,603
39	M03B6.1	M03B6.1	n/a	chrX 13,842,218
40	F21G4.1	F21G4.1	n/a	chrX 9,890,917	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF03137 (Organic Anion Transporter Polypeptide (OATP) family) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR004156 (Organic anion transporter polypeptide OATP), IPR000539 (Frizzled protein), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
41	tag-264	B0511.8	n/a	chrI 10,637,866	C. elegans TAG-264 protein; contains similarity to Pfam domain PF07147 Mitochondrial 28S ribosomal protein S30 (PDCD9) contains similarity to Interpro domain IPR010793 (Ribosomal protein S30, mitochondrial)
42	ubh-4	C08B11.7	n/a	chrII 8,038,864	C. elegans UBH-4 protein; contains similarity to Pfam domain PF01088 Ubiquitin carboxyl-terminal hydrolase, family 1 contains similarity to Interpro domains IPR001578 (Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1), IPR017390 (Ubiquitinyl hydrolase, UCH37 type)
43	mog-5	EEED8.5	n/a	chrII 5,402,615	The mog-5 gene encodes a DEAH helicase orthologous to the Drosophila CG8241, the human HRH1, and the S. cerevisiae PRP22 proteins.
44	tomm-7	ZK652.2	n/a	chrIII 7,859,778	C. elegans TOMM-7 protein; contains similarity to Pfam domain PF08038 TOM7 family contains similarity to Interpro domain IPR012621 (Mitochondrial import translocase, subunit Tom7)
45	K07G5.5	K07G5.5	n/a	chrI 7,171,105	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
46	rnf-121	C16C10.5	n/a	chrIII 4,169,952	C. elegans RNF-121 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
47	T24C12.3	T24C12.3	n/a	chrX 2,200,203	contains similarity to Pfam domains PF00294 (pfkB family carbohydrate kinase) , PF04227 (Indigoidine synthase A like protein) contains similarity to Interpro domains IPR011611 (Carbohydrate/purine kinase), IPR002139 (Ribokinase), IPR007342 (Indigoidine synthase A like protein), IPR002173 (Carbohydrate/puine kinase, PfkB, conserved site)
48	T01E8.6	T01E8.6	n/a	chrII 10,241,373	contains similarity to Pfam domain PF00253 Ribosomal protein S14p/S29e contains similarity to Interpro domain IPR001209 (Ribosomal protein S14)
49	C29F7.1	C29F7.1	n/a	chrX 13,413,508	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
50	Y48A6C.4	Y48A6C.4	n/a	chrIII 11,121,345	Y48A6C.4 encodes an ortholog of S. cerevisiae IPI1 that may suppress tumorous growth in the germline; like PRO-1, -2, and -3, Y48A6C.4 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline.