UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	W10G11.3	W10G11.3	2e-123	chrII 3,562,186	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
2	clec-118	W04H10.4	n/a	chrII 610,423	C. elegans CLEC-118 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
3	E02H9.1	E02H9.1	n/a	chrIII 2,468,952
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	fbxb-47	F58E1.14	n/a	chrII 1,702,944	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
6	Y75B8A.5	Y75B8A.5	n/a	chrIII 12,116,403	contains similarity to Interpro domain IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal)
7	ceh-10	W03A3.1	n/a	chrIII 5,800,012	ceh-10 encodes a member of the Paired-like class of homeodomain proteins; the CEH-10 homeodomain is closely related to the homeodomains of two vertebrate retina proteins (Chx10 from mice and Vsx-1 from goldfish); ceh-10 is required for CAN cell fate specification and migration, complete loss of ceh-10 function results in failure of CAN cell migration and loss of expression of CEH-23 and CEH-10 itself in the CAN and AIY interneurons; CEH-10, along with TTX-3 and CEH-23, constitutes a regulatory cascade of transcription factors that controls all sub-type specific features of the AIY interneurons.
8	srd-40	F17A2.12	n/a	chrX 12,324,508	C. elegans SRD-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	vps-32.2	C37C3.3	n/a	chrV 7,850,487	C. elegans VPS-32.2 protein; contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
10	F48B9.8	F48B9.8	n/a	chrX 2,175,203	contains similarity to Homo sapiens Protein FAM8A1; ENSEMBL:ENSP00000259963
11	T15B7.15	T15B7.15	n/a	chrV 6,837,660	contains similarity to Interpro domain IPR000533 (Tropomyosin)
12	F49C12.12	F49C12.12	n/a	chrIV 9,320,583	contains similarity to Homo sapiens RNase K; VG:OTTHUMP00000182776
13	F01G10.9	F01G10.9	n/a	chrIV 10,257,677	contains similarity to Interpro domain IPR000694 (Proline-rich region)
14	hlh-3	T24B8.6	n/a	chrII 9,086,866	hlh-3 encodes a basic helix-loop-helix transcription factor homologous to Drosophila Achaete-scute; in vitro, HLH-3 can heterodimerize, and bind an E-box-containing probe, with HLH-2, the C. elegans E/daughterless ortholog with which it is coexpressed in the nuclei of embryonic neuronal precursors.
15	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
16	R04B3.2	R04B3.2	n/a	chrX 2,472,601	The R04B3.2 gene encodes an ortholog of the human gene LYSOSOMAL GLYCOSYLASPARAGINASE (AGA; OMIM:208400), which when mutated leads to aspartylglucosaminuria (OMIM:208400).
17	C23H5.7	C23H5.7	n/a	chrIV 2,107,829	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000595 (Cyclic nucleotide-binding), IPR014710 (RmlC-like jelly roll fold)
18	F58H7.1	F58H7.1	n/a	chrIV 933,095	contains similarity to Homo sapiens Isoform 8 of Collagen alpha-2(XI) chain precursor; ENSEMBL:ENSP00000355123
19	F49E12.8	F49E12.8	n/a	chrII 8,393,450	contains similarity to Homo sapiens Hypothetical protein KIAA0335; TR:O15044
20	btb-12	ZC204.3	n/a	chrII 1,655,685	C. elegans BTB-12 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
21	W03F11.5	W03F11.5	n/a	chrI 2,217,759	n/a
22	H10E21.2	H10E21.2	n/a	chrIII 10,398	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
23	dpr-1	R10D12.2	n/a	chrV 13,941,139	dpr-1 encodes a putative nuclear hormone receptor that affects endoderm differentiation and may promote entry into the dauer state and maintenance of the dauer state; expressed in the endoderm lineage and localization appears dependent on growth conditions.
24	rnp-1	ZK863.7	n/a	chrV 12,193,297	C. elegans RNP-1 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1), IPR001878 (Zinc finger, CCHC-type)
25	set-30	ZC8.3	n/a	chrX 5,001,358	set-30 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-30 is paralogous to SET-10, SET-14, and SET-18; neither set-30(gk314) nor set-30(RNAi) have any obvious phenotypes.
26	bcc-1	M7.3	n/a	chrIV 11,089,293	bcc-1 encodes a homolog of Drosophila and vertebrate Bicaudal C (BICC) that contains KH RNA-binding domains, a serine-rich region, and a SAM (sterile alpha motif) domain; by homology, BCC-1 is predicted to function as a cytoplasmic RNA-binding protein that is required for translational regulation and/or mRNA stability during embryonic or germline development; however, as loss of bcc-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of BCC-1 in C. elegans development and/or behavior is not yet known.
27	cdc-42	R07G3.1	n/a	chrII 7,617,275	cdc-42 encodes a RHO GTPase which controls polarity of both individual cells and developing embryos by regulating the localization of PAR proteins; CDC-42 is expressed at hypodermal cell boundaries; cdc-42 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults.
28	ZK1055.3	ZK1055.3	n/a	chrV 6,590,794
29	srx-134	F09F3.7	n/a	chrV 13,855,910	C. elegans SRX-134 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	C15A7.2	C15A7.2	n/a	chrX 12,072,281	contains similarity to Xenopus laevis Transmembrane protein 145.; SW:Q5U239
31	ttb-1	W03F9.5	n/a	chrV 160,090	C. elegans TTB-1 protein; contains similarity to Pfam domains PF00382 (Transcription factor TFIIB repeat) (2), PF08271 (TFIIB zinc-binding) contains similarity to Interpro domains IPR006670 (Cyclin), IPR000812 (Transcription factor TFIIB related), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR013150 (Transcription factor TFIIB, cyclin-related), IPR013137 (Zinc finger, TFIIB-type)
32	rhgf-2	T08H4.1	n/a	chrII 4,124,087	C. elegans RHGF-2 protein; contains similarity to Pfam domain PF00621 RhoGEF domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR000694 (Proline-rich region), IPR011993 (Pleckstrin homology-type), IPR015721 (Rho GTP exchange factor)
33	F53C3.8	F53C3.8	n/a	chrII 3,891,751
34	clk-1	ZC395.2	n/a	chrIII 5,278,572	clk-1 encodes the C. elegans ortholog of COQ7/CAT5, a highly conserved demethoxyubiquinone (DMQ) hydroxylase that is necessary for the biosynthesis of ubiquinone (coenzyme Q, Q9) from 5-demethoxyubiquinone (DMQ9); in C. elegans, CLK-1 activity is required for normal physiological rates of growth, development, behavior, and aging, as well as for normal brood sizes.
35	sri-11	T22H2.3	n/a	chrI 11,696,802	C. elegans SRI-11 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
36	nhr-78	F36A4.14	n/a	chrIV 4,276,441	C. elegans NHR-78 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
37	F49D11.7	F49D11.7	n/a	chrI 10,923,733
38	C09G5.8	C09G5.8	n/a	chrII 10,723,744	contains similarity to Mus musculus Protein fantom (RPGR-interacting protein 1-like protein) (RPGRIP1-likesprotein).; SW:Q8CG73
39	F54E7.6	F54E7.6	n/a	chrIII 5,660,439
40	irx-1	C36F7.1	n/a	chrI 9,538,707	irx-1 encodes a homeodomain-containing protein that is most similar to members of the Iroquois subclass of TALE (three amino acid loop extension) superclass atypical homeodomain proteins; IRX-1 is predicted to function as a transcriptional regulator during development, but as loss of irx-1 activity via RNAi results in no obvious defects, the precise role of irx-1 in C. elegans development and/or behavior is not yet known.
41	mtm-5	H28G03.6	n/a	chrX 5,239,010	C. elegans MTM-5 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF06602 (Myotubularin-related) , PF02893 (GRAM domain) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR010569 (Myotubularin-related), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR005113 (uDENN), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding), IPR001194 (DENN), IPR004182 (GRAM)
42	H14E04.1	H14E04.1	n/a	chrIII 2,404,160	contains similarity to Pfam domains PF02353 (Cyclopropane-fatty-acyl-phospholipid synthase) , PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) , PF01209 (ubiE/COQ5 methyltransferase family) contains similarity to Interpro domains IPR004033 (UbiE/COQ5 methyltransferase), IPR003333 (Cyclopropane-fatty-acyl-phospholipid synthase), IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
43	fbxa-171	C38D9.1	n/a	chrV 17,564,573	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
44	srw-117	C44C3.6	n/a	chrV 2,982,800	C. elegans SRW-117 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
45	W05H5.1	W05H5.1	n/a	chrII 12,443,814	contains similarity to Ovis aries Lysophosphatidic acid receptor Edg-2 (LPA receptor 1) (LPA-1).; SW:EDG2_SHEEP
46	C15C7.6	C15C7.6	n/a	chrX 3,169,031	contains similarity to Interpro domain IPR003945 (NADH-plastoquinone oxidoreductase, chain 5)
47	tsr-1	F53G2.6	n/a	chrII 2,466,865	tsr-1 encodes a homolog of human transportin-SR, a nuclear transport receptor, and affects embryonic viability.
48	F43C1.5	F43C1.5	n/a	chrIII 4,229,767	contains similarity to Pfam domain PF02845 CUE domain contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR009060 (UBA-like)
49	K05F6.4	K05F6.4	n/a	chrII 1,544,461	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
50	Y39A3A.3	Y39A3A.3	n/a	chrIII 2,067,514	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))