UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srx-54	Y102A5C.22	2.9999999999999997e-166	chrV 16,975,937	C. elegans SRX-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	srg-17	F15A4.7	n/a	chrII 12,474,385	C. elegans SRG-17 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
4	F15E11.4	F15E11.4	n/a	chrV 2,340,462	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
5	srw-44	F14F8.6	n/a	chrV 16,681,440	C. elegans SRW-44 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
6	inft-2	F15B9.4	n/a	chrV 13,004,645	C. elegans INFT-2 protein; contains similarity to Pfam domain PF02181 Formin Homology 2 Domain contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR003104 (Actin-binding FH2 and DRF autoregulatory), IPR000976 (Wilm's tumour protein)
7	twk-35	F31D4.7	n/a	chrV 20,859,750	C. elegans TWK-35 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
8	F16B4.3	F16B4.3	n/a	chrV 1,597,417	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
9	F25E2.3	F25E2.3	n/a	chrX 812,150	contains similarity to Pfam domain PF02551 Acyl-CoA thioesterase contains similarity to Interpro domain IPR003703 (Acyl-CoA thioesterase)
10	Y70D2A.1	Y70D2A.1	n/a	chrX 14,922,327	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR000276 (GPCR, rhodopsin-like)
11	E03H12.4	E03H12.4	n/a	chrIV 4,982,952	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
12	C12D5.10	C12D5.10	n/a	chrV 7,692,770	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
13	prx-2	ZK809.7	n/a	chrIV 11,645,165	prx-2 is orthologous to the human gene PEROXISOMAL MEMBRANE PROTEIN 3 (PXMP3; OMIM:170993), which when mutated leads to Zellweger syndrome 3 or infantile Refsum disease.
14	C46H3.3	C46H3.3	n/a	chrX 1,228,487	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
15	egl-38	C04G2.7	n/a	chrIV 10,108,695	The egl-38 gene encodes a Pax5 homolog.
16	glb-8	C26C6.7	n/a	chrI 7,510,602	glb-8 encodes a globin with no obvious function in mass RNAi assays; glb-8 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-8 expression is downregulated in a daf-2(e1370) mutant background under normoxic conditions; glb-8 expression is lower in L3 larvae than in young adults or dauers.
17	srw-24	C41G6.7	n/a	chrV 15,224,639	C. elegans SRW-24 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
18	skr-6	Y37H2C.2	n/a	chrV 18,269,765	The skr-6 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-6(RNAi) animals are at least superficially normal.
19	T10B10.5	T10B10.5	n/a	chrX 15,197,450	contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
20	F47H4.2	F47H4.2	n/a	chrV 17,356,736	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
21	ZK643.7	ZK643.7	n/a	chrIII 8,925,977
22	F02C9.2	F02C9.2	n/a	chrV 3,135,542	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domains IPR005049 (Protein of unknown function DUF288), IPR002972 (Prostaglandin D synthase)
23	EEED8.12	EEED8.12	n/a	chrII 5,408,624	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
24	C31G12.3	C31G12.3	n/a	chrV 18,185,300	contains similarity to Rhodopirellula baltica Probable polysaccharide export protein.; TR:Q7UYB3
25	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
26	srb-15	C48B6.5	n/a	chrI 6,899,186	C. elegans SRB-15 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
27	Y53C10A.3	Y53C10A.3	n/a	chrI 11,969,389	Y53C10A.3 encodes a paralog of HSF-1 that might regulate ubq-1, since ubq-1 has 5'-flanking sequences resembling heat shock regulatory elements, yet is uninduced by heat shock.
28	col-123	W08D2.6	n/a	chrIV 9,822,477	col-123 is homologous to the human gene A TYPE IV COLLAGEN (COL6A1; OMIM:303631), which when mutated is sometimes associated with diffuse leiomyomatosis.
29	K11G9.5	K11G9.5	n/a	chrV 6,687,134	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
30	Y41C4A.13	Y41C4A.13	n/a	chrIII 11,735,378	contains similarity to Homo sapiens Rabconnectin; ENSEMBL:ENSP00000251076
31	spp-12	T22G5.7	n/a	chrV 13,890,091	C. elegans SPP-12 protein; contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
32	Y17D7C.2	Y17D7C.2	n/a	chrV 18,717,931	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
33	srbc-6	C36C5.3	n/a	chrV 3,170,772	C. elegans SRBC-6 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
34	F40D4.12	F40D4.12	n/a	chrV 17,161,146	contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
35	ocam-1	T02B5.2	n/a	chrV 14,167,452	T02B5.2 encodes a protein with an OCAM domain, a nematode-specific motif conserved between T02B5.2 and two other nematode ONECUT homeobox proteins (CEH-21 and CEH-41); this gene is probably derived from a ONECUT gene that lost both tit cut domain and its homeodomain; T02B5.2 has no obvious function in mass RNAi assays.
36	F26F2.7	F26F2.7	n/a	chrV 20,581,046	contains similarity to Pfam domain PF05346 Eukaryotic membrane protein family contains similarity to Interpro domain IPR008010 (Protein of unknown function DUF747, CMV receptor)
37	srx-67	K07C6.10	1e-38	chrV 3,917,627	C. elegans SRX-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
38	T21E12.2	T21E12.2	n/a	chrI 4,414,499	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
39	K10H10.5	K10H10.5	n/a	chrII 14,502,114	contains similarity to Interpro domain IPR001030 (Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)
40	nhr-132	R11G11.1	n/a	chrV 535,310	C. elegans NHR-132 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	C48E7.6	C48E7.6	n/a	chrI 6,244,688	contains similarity to Drosophila pseudoobscura GA10211-PA (Fragment).; TR:Q29MP8
42	T20D4.17	T20D4.17	n/a	chrV 3,395,750	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
43	C44H9.4	C44H9.4	n/a	chrV 12,837,723	contains similarity to Interpro domain IPR000839 (Porin, Oms28 type)
44	srz-95	Y102A5C.33	n/a	chrV 16,992,941	C. elegans SRZ-95 protein ;
45	scl-4	C39E9.1	n/a	chrIV 13,062,457	C. elegans SCL-4 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related), IPR000480 (Glutelin)
46	ire-1	C41C4.4	n/a	chrII 8,118,482	ire-1 encodes a transmembrane serine/threonine protein kinase and site-specific endoribonuclease orthologous to Saccharomyces cerevisiae inositol-requiring 1 protein kinase (Ire1) and human endoplasmic reticulum-to-nucleus signaling 1 (ERN1, OMIM:604033); IRE-1 is required for the unfolded protein response (UPR) that counteracts cellular stress induced by accumulation of unfolded proteins in the endoplasmic reticulum (ER); in response to ER stress, IRE-1 cleaves xbp-1 mRNA to produce transcriptionally active XBP-1 that positively regulates UPR gene expression in order to maintain ER homeostasis.
47	W02B3.3	W02B3.3	n/a	chrIII 668,260
48	M01B2.6	M01B2.6	n/a	chrV 15,242,739	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
49	ceh-28	K03A11.3	n/a	chrX 13,075,231	A homeobox protein of the NK-2 family; it is expressed in a single pharyngeal neuron, M4.
50	str-178	R11D1.5	n/a	chrV 12,715,427	C. elegans STR-178 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)