UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y39A1A.14	Y39A1A.14	1.9999999999999998e-130	chrIII 10,649,949	contains similarity to Pfam domain PF03587 Nep1 ribosome biogenesis protein contains similarity to Interpro domain IPR005304 (Suppressor Mra1)
2	C50F4.2	C50F4.2	n/a	chrV 9,533,151	C50F4.2 encodes a putative 6-phosphofructokinase, paralogous to Y71H10A.1; C50F4.2 is required for fertility, full body size, and normally rapid growth in mass RNAi assays; C50F4.2 transcripts are enriched during spermatogenesis.
3	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
4	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
5	F13C5.5	F13C5.5	n/a	chrX 606,710
6	B0280.11	B0280.11	n/a	chrIII 7,137,323	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
7	wrt-3	F38E11.7	n/a	chrIV 9,476,571	wrt-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a region of low-complexity sequence; WRT-3 is expressed in the trinucleate pharyngeal gland cell g1 beginning at the three-fold stage of embryogenesis, in seam cells and hypodermis, and in single muscle cells and the distal tip cells of late stage larvae and adults; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-3 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
8	srx-78	C01G10.3	n/a	chrV 15,096,226	C. elegans SRX-78 protein
9	F01G12.6	F01G12.6	n/a	chrX 16,401,117	contains similarity to Drosophila melanogaster Flybase gene name is CG11727-PA;; FLYBASE:CG11727
10	T22D1.12	T22D1.12	n/a	chrIV 6,930,087	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
11	Y54G9A.4	Y54G9A.4	n/a	chrII 13,714,353	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
12	F41H10.2	F41H10.2	n/a	chrIV 5,381,978
13	ari-1	C27A12.8	n/a	chrI 6,059,904	C. elegans ARI-1 protein; contains similarity to Pfam domain PF01485 IBR domain contains similarity to Interpro domains IPR009060 (UBA-like), IPR002867 (Zinc finger, C6HC-type)
14	C06C3.8	C06C3.8	n/a	chrII 9,388,665	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domains IPR005020 (Protein of unknown function DUF278), IPR001984 (Peptidase S16, Lon protease), IPR006578 (MADF)
15	tag-141	C30H6.2	n/a	chrIV 17,365,684	tag-141/C30H6.2 encodes a putative zinc transporter orthologous to human SLC39A4 (OMIM:607059, mutated in acrodermatitis enteropathica).
16	srh-213	T22F3.5	n/a	chrV 3,593,857	C. elegans SRH-213 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	lin-52	ZK632.13	n/a	chrIII 9,824,348	lin-52 encodes a novel protein that is most closely related to the Drosophila melanogaster CG15929 protein and the human protein XP_040376; lin-52 is a class B synthetic multivulva (synMuv) gene that appears to function with lin-35/Rb to negatively regulate vulval development; in addition, lin-52 is also required for germline and larval development.
18	sre-1	B0495.1	n/a	chrII 7,710,540	sre-1 encodes a putative seven transmembrane chemoreceptor; an SRE-1::GFP reporter is expressed in the ADL and ASJ amphid sensory neurons.
19	ubq-2	ZK1010.1	n/a	chrIII 12,978,145	ubq-2 encodes a bifunctional protein that contains two domains; an N-terminal ubiquitin peptide, and a C-terminal large ribosomal subunit protein L40 peptide.
20	grl-29	T24A6.18	n/a	chrV 3,554,921	grl-29 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-29 is expressed in larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
21	lact-1	F46H5.8	n/a	chrX 7,259,241	lact-1 encodes a beta-lactamase domain-containing protein.
22	fbxa-218	Y49E10.17	n/a	chrIII 12,438,684	C. elegans FBXA-218 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
23	T19D2.1	T19D2.1	n/a	chrX 3,935,349	contains similarity to Pfam domains PF00090 (Thrombospondin type 1 domain) (4), PF01421 (Reprolysin (M12B) family zinc metalloprotease) contains similarity to Interpro domains IPR008085 (Thrombospondin, subtype 1), IPR000884 (Thrombospondin, type I), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR013273 (Peptidase M12B, ADAM-TS), IPR001590 (Peptidase M12B, ADAM/reprolysin)
24	D2089.2	D2089.2	n/a	chrII 10,660,588	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
25	Y38H6C.15	Y38H6C.15	n/a	chrV 20,530,900	contains similarity to Interpro domain IPR006017 (Caldesmon)
26	T06E4.5	T06E4.5	n/a	chrV 9,631,723	contains similarity to Interpro domains IPR001046 (Natural resistance-associated macrophage protein), IPR001266 (Ribosomal protein S19e)
27	pad-1	Y18D10A.13	n/a	chrI 12,890,677	The pad-1 gene encodes a highly conserved, but unfamiliar, protein that is required for embryonic development.
28	C33C12.4	C33C12.4	n/a	chrII 2,165,992
29	fbxa-90	Y102A5C.19	n/a	chrV 16,967,704	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
30	pgp-4	F42E11.1	n/a	chrX 11,361,531	pgp-4 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-4 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-4 activity via deletion mutations or RNAi results in no obvious defects, the precise role of PGP-4 in C. elegans development and/or behavior is not yet known; pgp-4 promoter-gfp fusion proteins are expressed in the larval excretory cell.
31	str-214	C31A11.9	n/a	chrV 16,316,238	C. elegans STR-214 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	srbc-44	ZC455.9	n/a	chrV 12,787,889	C. elegans SRBC-44 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
33	F40F12.4	F40F12.4	n/a	chrIII 9,895,687	contains similarity to Interpro domain IPR000998 (MAM)
34	T08D10.3	T08D10.3	n/a	chrX 11,956,831	contains similarity to Homo sapiens Hypothetical protein KIAA1681; ENSEMBL:ENSP00000316543
35	T22D1.1	T22D1.1	n/a	chrIV 6,924,455	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR008166 (Protein of unknown function DUF23)
36	F20B4.3	F20B4.3	n/a	chrX 17,706,033
37	F58H7.2	F58H7.2	n/a	chrIV 942,839	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR015830 (Amidase, fungi type)
38	prx-13	F32A5.6	n/a	chrII 7,251,051	prx-13 is orthologous to the human gene PEX13 (OMIM:601789), which when mutated leads to Zellweger syndrome or neonatal adrenoleukodystrophy.
39	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
40	F48B9.2	F48B9.2	n/a	chrX 2,173,341
41	F20G2.5	F20G2.5	n/a	chrV 13,772,581	contains similarity to Pfam domain PF02408 (Domain of unknown function DUF141)
42	F08D12.2	F08D12.2	n/a	chrII 2,782,368	contains similarity to Pfam domain PF04942 CC domain contains similarity to Interpro domain IPR007026 (Domian of unknown function, DUF-CC)
43	F53B6.5	F53B6.5	n/a	chrI 8,950,742	contains similarity to Pfam domain PF00557 metallopeptidase family M24 contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR011991 (Winged helix repressor DNA-binding)
44	C06A5.10	C06A5.10	n/a	chrI 5,982,746
45	eif-3.G	F22B5.2	n/a	chrII 8,443,436	eif-3.G encodes a homolog of eukaryotic translation initiation factor 3, subunit 4 that affects embryonic viability, fertility, and growth.
46	acr-23	F59B1.9	n/a	chrV 3,655,579	acr-23 encodes an alpha 7-like homomer-forming subunit of the nicotinic acetylcholine receptor (nAChR) superfamily which encode ligand-gated ion channels that regulate fast action of acetylcholine at neuromuscular junctions and in the nervous system; ACR-23 is a member of the DEG-3-like group of nAChR subunits which appears to be unique to nematodes.
47	K07D4.6	K07D4.6	n/a	chrII 4,017,758	contains similarity to Drosophila melanogaster Flybase gene name is CG31439-PA;; FLYBASE:CG31439
48	W01C9.4	W01C9.4	n/a	chrII 8,546,188	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
49	T15B7.6	T15B7.6	n/a	chrV 6,826,715
50	kcc-1	R13A1.2	n/a	chrIV 7,215,841	C. elegans KCC-1 protein; contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR000076 (K-Cl co-transporter), IPR004841 (Amino acid permease-associated region), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)