UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y56A3A.16	Y56A3A.16	0	chrIII 11,912,267	contains similarity to Homo sapiens Isoform 1 of Pleckstrin homology domain-containing family M member 3; ENSEMBL:ENSP00000373899
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C26C6.8	C26C6.8	n/a	chrI 7,504,574	contains similarity to Pfam domains PF07653 (Variant SH3 domain) (3), PF00018 (SH3 domain) (2)contains similarity to Interpro domains IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR011511 (Variant SH3)
4	nhr-83	F48G7.3	n/a	chrV 632,120	C. elegans NHR-83 protein; contains similarity to Pfam domains PF07914 (Protein of unknown function (DUF1679)) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core), IPR015897 (CHK kinase-like)
5	F28H6.6	F28H6.6	n/a	chrX 14,121,403	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
6	Y69H2.1	Y69H2.1	n/a	chrV 18,621,264	contains similarity to Myxine glutinosa NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3).; SW:NU4M_MYXGL
7	C47D12.8	C47D12.8	n/a	chrII 11,700,677	C47D12.8 encodes an ortholog of the DNA repair protein XPF/ERCC4, which when mutated in humans leads to xeroderma pigmentosum (complementation group F; OMIM:133520); C47D12.8(RNAi) animals are hypersensitive to ultraviolet radiation, with increased germ cell apoptosis and embryonic lethality; C47D12.8 protein interacts with F10G8.7 (an ERCC1 ortholog) in yeast two-hybrid assays; C47D12.8 is expressed broadly in both embryonic and postembryonic animals, and is required for embryonic development; C47D12.8 is upregulated in dauers, and shares an operon with kel-1 and VF13D12L.3.
8	nhr-189	F47C10.8	n/a	chrV 3,859,413	C. elegans NHR-189 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
9	C23H5.7	C23H5.7	n/a	chrIV 2,107,829	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) , PF00520 (Ion transport protein) contains similarity to Interpro domains IPR005821 (Ion transport), IPR000595 (Cyclic nucleotide-binding), IPR014710 (RmlC-like jelly roll fold)
10	dpr-1	R10D12.2	n/a	chrV 13,941,139	dpr-1 encodes a putative nuclear hormone receptor that affects endoderm differentiation and may promote entry into the dauer state and maintenance of the dauer state; expressed in the endoderm lineage and localization appears dependent on growth conditions.
11	tbx-32	ZK380.1	n/a	chrX 1,656,225	C. elegans TBX-32 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
12	W02D9.9	W02D9.9	n/a	chrI 12,557,310	contains similarity to Bacteroides thetaiotaomicron Arabinose-proton symporter (Arabinose transporter).; TR:Q8AAL0
13	sdc-2	C35C5.1	n/a	chrX 11,528,006	The sdc-2 gene encodes a protein that represses transcription of X chromosomes to achieve dosage compensation, and that also represses the male sex-determination gene her-1 to elicit hermaphrodite differentiation.
14	nhr-32	K08H2.8	n/a	chrX 13,254,014	C. elegans NHR-32 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	bath-33	C08E3.3	n/a	chrII 1,605,408	C. elegans BATH-33 protein; contains similarity to Pfam domains PF00917 (MATH domain) , PF00651 (BTB/POZ domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
16	C13C4.6	C13C4.6	n/a	chrV 12,123,359	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
17	F47G6.3	F47G6.3	n/a	chrI 1,467,585	contains similarity to Homo sapiens Putative uncharacterized protein (Fragment); ENSEMBL:ENSP00000333119
18	sri-11	T22H2.3	n/a	chrI 11,696,802	C. elegans SRI-11 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
19	sre-37	F15A4.3	n/a	chrII 12,466,610	C. elegans SRE-37 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
20	R07E5.5	R07E5.5	n/a	chrIII 4,398,025	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
21	T03E6.2	T03E6.2	n/a	chrV 16,582,078	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	ced-3	C48D1.2	n/a	chrIV 13,202,258	The ced-3 gene encodes a protease required for apoptosis.
23	npr-1	C39E6.6	n/a	chrX 4,768,551	npr-1 encodes a predicted G protein-coupled neuropeptide receptor that is homologous to the mammalian neuropeptide Y (NPY) receptor (OMIM:162641) required for regulating anxiety, food consumption, and pain sensation; in C. elegans, NPR-1 is involved in ethological variations of social behavior such as social versus solitary feeding; NPR-1 also affects some aspect of UNC-6/netrin-mediated branching of motor neurons, as strong npr-1 mutations can suppress abnormal migration of ventral nerve cord neurons induced by overexpression of UNC-6 lacking domain C; NPR-1 is expressed predominantly in the nervous system, and particularly in the AQR, PQR, and URX neurons that are exposed to the body fluid.
24	acr-3	K11G12.7	n/a	chrX 6,711,143	acr-3 encodes a non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; ACR-3 functions as a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with UNC-38, an nAChR alpha subunit, the resulting hetero-oligomer can form levamisole-gated channels; ACR-3 is a member of the UNC-29-like group of nAChR subunits.
25	C23H4.2	C23H4.2	n/a	chrX 12,221,143	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR002018 (Carboxylesterase, type B)
26	sri-25	C41G6.10	n/a	chrV 15,218,422	C. elegans SRI-25 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	C31H1.7	C31H1.7	n/a	chrIV 5,809,426
28	F38C2.1	F38C2.1	n/a	chrIV 16,249,570	contains similarity to Carnobacterium piscicola ATP-dependent translocator.; TR:Q46317
29	srw-103	ZK697.5	n/a	chrV 1,718,354	C. elegans SRW-103 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
30	F54E7.6	F54E7.6	n/a	chrIII 5,660,439
31	rbr-2	ZK593.4	n/a	chrIV 10,923,428	rbr-2 encodes a histone H3 lysine 4 (H3K4) demethylase that is required for normally short lifespan and reliable vulval development, that regulates genome-wide levels of H3K4 trimethylation, and that interacts genetically with CLK-2, GLP-1, LIN-15, and SEM-5; RBR-2 is orthologous to budding yeast Jhd2p, Drosophila LID, and human JARID1A (OMIM:180202), JARID1B (OMIM:605393), JARID1C (OMIM:314690, mutated in mental retardation), and JARID1D (OMIM:426000); rbr-2(tm1231) homozygotes display excess trimethylated H3K4 (H3K4me3) and erratic vulval development (either vulvaless or multivulva); rbr-2(RNAi) animals show extended lifespans, a strong synthetic multivulva and H3K4me3 phenotype in a lin-15(n765ts) mutant background at permissive temperature, and abnormally slow growth with clk-2(mn159), glp-1(or178), or sem-5(n2019) mutant backgrounds.
32	fbxa-203	W05F2.5	n/a	chrI 3,372,801	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
33	C08G5.1	C08G5.1	n/a	chrII 736,664	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
34	C01G6.9	C01G6.9	n/a	chrII 9,294,851	contains similarity to Plasmodium falciparum SET-domain protein, putative.; TR:Q8IC77
35	F31F7.3	F31F7.3	n/a	chrV 6,269,506
36	C15A7.2	C15A7.2	n/a	chrX 12,072,281	contains similarity to Xenopus laevis Transmembrane protein 145.; SW:Q5U239
37	srbc-65	Y32B12B.3	n/a	chrV 16,551,603	C. elegans SRBC-65 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
38	srh-235	F08E10.1	n/a	chrV 17,470,910	C. elegans SRH-235 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	srh-248	H05B21.2	n/a	chrV 2,954,922	C. elegans SRH-248 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000215 (Protease inhibitor I4, serpin)
40	C50C3.7	C50C3.7	n/a	chrIII 8,160,210	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domains IPR000300 (Inositol polyphosphate related phosphatase), IPR005135 (Endonuclease/exonuclease/phosphatase)
41	scl-8	C39E9.6	n/a	chrIV 13,072,085	C. elegans SCL-8 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
42	C47E8.6	C47E8.6	n/a	chrV 14,690,485	contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
43	K09D9.12	K09D9.12	n/a	chrV 4,003,740
44	C03B1.3	C03B1.3	n/a	chrX 6,366,380
45	C25G6.3	C25G6.3	n/a	chrX 1,235,994	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR011130 (SecA preprotein cross-linking region), IPR007087 (Zinc finger, C2H2-type)
46	W02D9.8	W02D9.8	n/a	chrI 12,558,734	contains similarity to Interpro domain IPR004692 (Preprotein translocase SecG subunit)
47	srw-14	C41G6.8	n/a	chrV 15,226,687	C. elegans SRW-14 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000975 (Interleukin-1)
48	H42K12.2	H42K12.2	n/a	chrX 1,319,512
49	set-24	Y43F11A.5	n/a	chrII 12,122,894	set-24 encodes a protein with an N-terminal SET domain, followed by two SPK domains; SET-24's domain organization resembles that of SET-5, but SET-24 has no known non-nematode orthologs or C. elegans paralogs; neither set-24(n4909) nor set-24(RNAi) have any obvious phenotypes.
50	srd-40	F17A2.12	n/a	chrX 12,324,508	C. elegans SRD-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)