UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	lgg-2	ZK593.6	4.9999999999999997e-64	chrIV 10,935,264	lgg-2 encodes an ortholog of the autophagic budding yeast protein Atg8p; LGG-2 is also homologous the light chain 3 (LC3) subunit of the microtubule-associated proteins 1A and 1B (MAP1A and MAP1B); LGG-2 is predicted to associate with MAP1A and MAP1B and with microtubules and to perhaps play a role in regulating the microtubule-binding activity of MAP1A and MAP1B; LGG-2 has no obvious function in RNAi assays, and is not required for either dauer formation or extended lifespan.
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	K12H4.6	K12H4.6	n/a	chrIII 8,042,653
4	F46B3.7	F46B3.7	n/a	chrV 20,613,776	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
5	Y44A6C.1	Y44A6C.1	n/a	chrV 20,710,785	contains similarity to Plasmodium falciparum Normocyte binding protein 2b.; TR:Q7YWE8
6	grd-9	C04E6.6	n/a	chrV 5,896,978	grd-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-9 is weakly required for normal molting; GRD-9 is also required for normal growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
7	C49H3.12	C49H3.12	n/a	chrIV 7,927,035
8	B0222.2	B0222.2	n/a	chrV 9,136,662	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domain IPR001204 (Phosphate transporter)
9	K01D12.10	K01D12.10	n/a	chrV 12,406,600	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR003072 (Orphan nuclear receptor, NOR1 type), IPR003982 (Leukotriene B4 type 2 receptor)
10	C01G6.4	C01G6.4	n/a	chrII 9,272,092	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
11	Y43F8B.9	Y43F8B.9	n/a	chrV 19,479,769
12	F21D9.3	F21D9.3	n/a	chrV 19,257,632	contains similarity to Hepatitis B virus Large S protein (Major surface antigen).; TR:Q8JXA0
13	M01E10.3	M01E10.3	n/a	chrIII 2,054,148	contains similarity to Interpro domain IPR016187 (C-type lectin fold)
14	ttr-37	F21E9.3	n/a	chrX 1,336,135	C. elegans TTR-37 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
15	Y43F8C.5	Y43F8C.5	n/a	chrV 19,631,978	contains similarity to Dictyostelium discoideum Myb-like protein (Fragment).; SW:MYBH_DICDI
16	F15E6.4	F15E6.4	n/a	chrIV 4,291,666
17	gbh-2	M05D6.7	n/a	chrII 8,486,654	gbh-2 encodes an ortholog of human gamma butyrobetaine hydroxilase 2 involved in carnitine biosynthesis; RNA interference of gbh-2 results in malformation of the gonad and accumulation of fat in the pseudocoelomic cavity and in intestinal cells; the GBH-2-GFP fusion protein is predominantly expressed in intestinal cells from early embryogenesis.
18	F48C1.8	F48C1.8	n/a	chrI 5,335,938	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein)
19	R03H10.5	R03H10.5	n/a	chrII 4,170,159	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
20	str-106	K05D4.2	n/a	chrV 16,181,228	C. elegans STR-106 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	ceh-48	C17H12.9	n/a	chrIV 6,813,828	ceh-48 encodes a ONECUT class CUT homeobox protein with a single N-terminal cut domain; the cut domain may be a compact DNA-binding domain composed of alpha helices; CEH-48 is strongly affiliated with, and may be orthologous to, Drosophila ONECUT and mammalian HNF6 proteins; ceh-48 has no obvious function in mass RNAi assays.
22	med-1	T24D3.1	n/a	chrX 12,430,862	The med-1 gene encodes a GATA-type transcription factor that is an immediate target of maternal SKN-1, and that participates in specifying the mesendoderm.
23	ZC373.2	ZC373.2	n/a	chrX 10,058,054	contains similarity to Synechococcus elongatus Tll2335 protein.; TR:Q8DGI2
24	ZC196.3	ZC196.3	n/a	chrV 8,737,532	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domain IPR007883 (Protein of unknown function DUF713)
25	nhr-77	T15D6.6	n/a	chrI 12,384,994	C. elegans NHR-77 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
26	B0281.6	B0281.6	n/a	chrII 2,301,816	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR000210 (BTB/POZ-like)
27	srz-100	T25E12.11	n/a	chrV 16,732,494	C. elegans SRZ-100 protein ;
28	dct-14	Y38H6C.3	n/a	chrV 20,495,572	C. elegans DCT-14 protein ; contains similarity to Rhizopus oryzae FK506-binding protein 4 (EC 5.2.1.8) (Peptidyl-prolyl cis-transsisomerase) (PPIase) (Rotamase).; SW:P0C1J6
29	nhr-281	F16B12.8	n/a	chrX 14,112,277	C. elegans NHR-281 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	F08H9.4	F08H9.4	n/a	chrV 14,463,959	F08H9.4 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the excretory canal and ventral nerve-cord neurons), and its expression is only mildly induced by heat shock; however, F08H9.4 expression is increased by heat shock, is induced in a new tissue type (intestine) by heat shock, and probably aids heat shock resistance, since F08H9.4(RNAi) animals die as embryos in heat shock at a higher rate than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.
31	C17C3.3	C17C3.3	n/a	chrII 5,562,616	contains similarity to Pfam domain PF02551 Acyl-CoA thioesterase contains similarity to Interpro domain IPR003703 (Acyl-CoA thioesterase)
32	C17A2.4	C17A2.4	n/a	chrII 3,840,560	contains similarity to Cebus apella Galactoside 2-alpha-L-fucosyltransferase 1 (EC 2.4.1.69) (GDP-L-sfucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1)s(Alpha(1,2)FT 1) (Fucosyltransferase 1).; SW:Q866E8
33	T05F1.7	T05F1.7	n/a	chrI 9,640,961	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_33, whole genome shotgun sequence.; TR:A0D056
34	djr-1.2	C49G7.11	n/a	chrV 4,054,635	C. elegans DJR-1.2 protein; contains similarity to Pfam domain PF01965 DJ-1/PfpI family contains similarity to Interpro domains IPR006287 (DJ-1), IPR002818 (ThiJ/PfpI)
35	grl-20	C23H5.9	n/a	chrIV 2,127,497	grl-20 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
36	C18H7.9	C18H7.9	n/a	chrIV 603,317	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
37	ugt-36	F09G2.6	n/a	chrV 7,168,088	C. elegans UGT-36 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR008081 (Cytoplasmic FMR1-interacting), IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
38	clec-264	F31D4.4	n/a	chrV 20,844,595	C. elegans CLEC-264 protein; contains similarity to Pfam domains PF01466 (Skp1 family, dimerisation domain) , PF03931 (Skp1 family, tetramerisation domain) contains similarity to Interpro domains IPR001232 (SKP1 component), IPR016072 (SKP1 component, dimerisation), IPR011333 (BTB/POZ fold), IPR016073 (SKP1 component, POZ)
39	C34D1.4	C34D1.4	n/a	chrV 13,258,178
40	srh-100	C46E10.10	n/a	chrII 3,713,935	C. elegans SRH-100 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	F23A7.1	F23A7.1	n/a	chrX 16,217,447	contains similarity to Saccharomyces cerevisiae RSC4 is a member of RSC complex, which remodels the structure of chromatin.; SGD:YKR008W
42	M176.8	M176.8	n/a	chrII 9,437,409	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
43	srh-258	T06E6.7	n/a	chrV 15,405,935	C. elegans SRH-258 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
44	far-4	F15B9.2	n/a	chrV 12,999,023	far-4 encodes a fatty acid and retinol-binding protein, paralogous to FAR-3 and FAR-5 and distantly homologous to FAR proteins of parasitic nematodes; FAR-4 binds lipids in vitro; far-4 is transcribed at highest levels in the fourth larval stage, and is dispensable for viability and gross morphology in mass RNAi assays.
45	T27E4.1	T27E4.1	n/a	chrV 9,093,497	contains similarity to Interpro domain IPR008973 (C2 calcium/lipid-binding region, CaLB)
46	F22B7.3	F22B7.3	n/a	chrIII 8,649,167
47	F35E2.3	F35E2.3	n/a	chrI 11,735,172	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
48	spp-9	T25C12.2	n/a	chrX 11,487,901	C. elegans SPP-9 protein; contains similarity to Pfam domain PF03489 Saposin-like type B, region 2 contains similarity to Interpro domains IPR008138 (Saposin-like type B, 2), IPR011001 (Saposin-like), IPR008139 (Saposin B)
49	K09D9.9	K09D9.9	n/a	chrV 3,993,382
50	ttr-4	F40F12.1	n/a	chrIII 9,916,526	sdz-17 encodes a protein that contains a transthyretin-like domain; SDZ-17 belongs to a family of apparently nematode-specific proteins whose function is not yet known; early zygotic expression of sdz-17 is dependent upon the SKN-1 transcription factor.