UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ckb-2	B0285.9	0	chrIII 4,368,967	ckb-2 encodes an isoform of choline kinase whose activity has been verified in vitro; CKB-1 through CKB-4 comprise a related group ('B') of choline kinases; purified CKB-2 has a strong preference for choline over ethanolamine, a specific activity of 2.4 micromol/min/mg protein and a pH optimum near 10.
2	W10G11.17	W10G11.17	n/a	chrII 3,564,777
3	gst-6	F11G11.3	n/a	chrII 4,880,483	gst-6 encodes a predicted glutathione S-transferase.
4	gpa-18	W03F8.9	n/a	chrIV 5,192,340	gpa-18 encodes a divergent G protein alpha subunit, with roughly as much similarity to fungal as to metazoan homologs.
5	H25P06.1	H25P06.1	n/a	chrI 11,317,448	contains similarity to Pfam domains PF00349 (Hexokinase) , PF03727 (Hexokinase) contains similarity to Interpro domain IPR001312 (Hexokinase)
6	C01F1.1	C01F1.1	n/a	chrII 4,303,435	contains similarity to Pfam domain PF05793 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) contains similarity to Interpro domains IPR011991 (Winged helix repressor DNA-binding), IPR008851 (Transcription initiation factor IIF, alpha subunit), IPR011039 (Transcription Factor IIF, Rap30/Rap74, interaction)
7	cyp-33E2	F42A9.5	n/a	chrIV 8,613,501	C. elegans CYP-33E2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
8	cdd-1	C47D2.2	n/a	chrX 8,209,904	cdd-1 encodes a cytidine deaminase that contains a zinc-binding region; expressed in the intestine.
9	F39H12.1	F39H12.1	n/a	chrX 836,268	contains similarity to Homo sapiens nuclear pore complex-associated protein TPR; ENSEMBL:ENSP00000356448
10	T24D11.1	T24D11.1	n/a	chrX 16,409,674	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
11	VT23B5.2	VT23B5.2	n/a	chrIV 12,671,338	VT23B5.2 encodes a BEACH-WD40 domain-containing protein that is orthologous to human WDFY3 (WD repeat and FYVE domain containing 3); loss of VT23B5.2 activity via mutation or large-scale RNAi screens in a wild-type background results in no obvious abnormalities.
12	lips-10	F14E5.5	n/a	chrII 8,440,581	C. elegans LIPS-10 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
13	T22H9.4	T22H9.4	n/a	chrV 335,754	contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
14	W04E12.7	W04E12.7	n/a	chrV 19,731,742	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
15	xrn-2	Y48B6A.3	n/a	chrII 14,160,796	C. elegans XRN-2 protein; contains similarity to Pfam domain PF03159 XRN 5'-3' exonuclease N-terminus contains similarity to Interpro domains IPR017151 (5'-3' exoribonuclease 2), IPR004859 (Putative 5-3 exonuclease), IPR002952 (Eggshell protein), IPR001878 (Zinc finger, CCHC-type)
16	R03H10.7	R03H10.7	n/a	chrII 4,177,232	contains similarity to Pfam domain PF01336 OB-fold nucleic acid binding domain contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR004365 (Nucleic acid binding, OB-fold, tRNA/helicase-type)
17	lgc-21	C33G3.3	n/a	chrX 14,065,977	C. elegans LGC-21 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
18	sri-51	ZC239.8	n/a	chrII 3,198,350	C. elegans SRI-51 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	F36F12.7	F36F12.7	n/a	chrV 2,099,700
20	Y54G11A.4	Y54G11A.4	n/a	chrII 14,294,300	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR000023 (Phosphofructokinase)
21	fbxa-156	C06H5.1	n/a	chrV 17,896,012	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
22	pgp-4	F42E11.1	n/a	chrX 11,361,531	pgp-4 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-4 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-4 activity via deletion mutations or RNAi results in no obvious defects, the precise role of PGP-4 in C. elegans development and/or behavior is not yet known; pgp-4 promoter-gfp fusion proteins are expressed in the larval excretory cell.
23	C06E4.3	C06E4.3	n/a	chrIV 7,261,440	contains similarity to Pfam domains PF07993 (Male sterility protein) , PF01370 (NAD dependent epimerase/dehydratase family) , PF00106 (short chain dehydrogenase) contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR001509 (NAD-dependent epimerase/dehydratase), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR013120 (Male sterility, NAD-binding)
24	E01G6.1	E01G6.1	n/a	chrX 12,263,633	contains similarity to Pfam domains PF00027 (Cyclic nucleotide-binding domain) (2), PF01734 (Patatin-like phospholipase) contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin), IPR000595 (Cyclic nucleotide-binding), IPR001423 (Lysophospholipase patatin, conserved site), IPR014710 (RmlC-like jelly roll fold)
25	R13A5.10	R13A5.10	n/a	chrIII 7,582,468	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016193 (Cytidine deaminase-like)
26	kin-3	B0205.7	n/a	chrI 10,735,304	kin-3 encodes an ortholog of the catalytic subunit of casein kinase II alpha, which in Drosophila and mammals is required for normal circadian rhythms, and which directly phosphorylates the Drosophila PERIOD protein (which itself regulates circadian rhythms); by analogy, KIN-3 might be expected to help regulate heterochronic functions dependent on such proteins as LIN-42.
27	B0238.13	B0238.13	n/a	chrV 5,245,859	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
28	str-214	C31A11.9	n/a	chrV 16,316,238	C. elegans STR-214 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	F38A1.8	F38A1.8	n/a	chrIV 1,236,362	contains similarity to Pfam domains PF00448 (SRP54-type protein, GTPase domain) , PF02881 (SRP54-type protein, helical bundle domain) , PF04086 (Signal recognition particle, alpha subunit, N-terminal) contains similarity to Interpro domains IPR007222 (Signal recognition particle receptor, alpha subunit, N-terminal), IPR000897 (Signal recognition particle, SRP54 subunit, GTPase), IPR011012 (Longin-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR003593 (AAA+ ATPase, core)
30	nhr-62	Y67A6A.2	n/a	chrI 9,842,194	C. elegans NHR-62 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	kel-1	C47D12.7	n/a	chrII 11,692,402	kel-1 encodes a BTB/POZ- and Kelch motif-containing protein orthologous to Drosophila Kelch, which is essential for actin organization in ovarian ring canals; in C. elegans, kel-1 is required for regulating feeding during larval development and more specifically, for pharyngeal isthmus peristalsis and efficient trapping of food in the pharynx; KEL-1 is first expressed at the 1.5-fold stage of embryogenesis in the pharyngeal lumen and the nerve ring; later adult and larval expression is confined to the pharyngeal gland cells in which KEL-1 may be required for maintenance of gland cell-specific structures.
32	M02F4.3	M02F4.3	n/a	chrX 3,038,574	M02F4.3 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C33D12.2, C52D10.12, R04E5.2, and R13G10.4; by orthology with MAM3, M02F4.3 may participate in metal homoeostasis; M02F4.3, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; M02F4.3 has no obvious function in RNAi assays.
33	M01G12.9	M01G12.9	n/a	chrI 12,111,806	contains similarity to Lactococcus lactis ORF (Fragment).; TR:Q48730
34	F29B9.10	F29B9.10	n/a	chrIV 4,659,258	contains similarity to Interpro domain IPR001911 (Ribosomal protein S21)
35	F58H7.2	F58H7.2	n/a	chrIV 942,839	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR015830 (Amidase, fungi type)
36	grl-29	T24A6.18	n/a	chrV 3,554,921	grl-29 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-29 is expressed in larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
37	prx-13	F32A5.6	n/a	chrII 7,251,051	prx-13 is orthologous to the human gene PEX13 (OMIM:601789), which when mutated leads to Zellweger syndrome or neonatal adrenoleukodystrophy.
38	pmp-2	C44B7.9	n/a	chrII 6,885,843	C. elegans PMP-2 protein; contains similarity to Pfam domains PF06472 (ABC transporter transmembrane region 2) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR011527 (ABC transporter, transmembrane region, type 1), IPR010509 (ABC transporter, N-terminal), IPR003593 (AAA+ ATPase, core), IPR005283 (Peroxysomal long chain fatty acyl transporter)
39	F18A11.2	F18A11.2	n/a	chrII 13,034,546	contains similarity to Pfam domain PF00650 CRAL/TRIO domain contains similarity to Interpro domains IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal)
40	T04F8.6	T04F8.6	n/a	chrX 11,669,654	contains similarity to Interpro domain IPR011992 (EF-Hand type)
41	T20B12.1	T20B12.1	n/a	chrIII 7,388,607	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (3), PF00515 (Tetratricopeptide repeat) (4)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR001664 (Intermediate filament protein), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR001356 (Homeobox), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
42	C15B12.1	C15B12.1	n/a	chrX 6,477,878	contains similarity to Pfam domain PF01266 FAD dependent oxidoreductase contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR016040 (NAD(P)-binding)
43	F20B4.3	F20B4.3	n/a	chrX 17,706,033
44	Y45F10D.7	Y45F10D.7	n/a	chrIV 13,792,547	Y45F10D.7 encodes a WD40 repeat-containing protein that is the C. elegans ortholog of human WDR36, mutations in which cause primary open angle glaucoma type 1G (GLC1G, OMIM:609887); large-scale RNAi experiments indicate that Y45F10D.7 activity is required for embryonic and larval development; the Saccharomyces cerevisiae homolog of WDR36, Utp21, is a component of the small-subunit (SSU) processome required for formation of 18S rRNA.
45	C01F1.2	C01F1.2	n/a	chrII 4,300,243	C01F1.2 is orthologous to the human gene SCO (CYTOCHROME OXIDASE DEFICIENT, YEAST) HOMOLOG 1 (SCO1; OMIM:603644), which when mutated leads to early-onset hepatic failure; the C01F1.2 protein is predicted to be mitochondrial with 68% accuracy.
46	C06H5.6	C06H5.6	n/a	chrV 17,884,381	contains similarity to Pfam domains PF00083 (Sugar (and other) transporter) , PF07690 (Major Facilitator Superfamily) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
47	sre-27	Y57A10C.3	n/a	chrII 12,416,469	C. elegans SRE-27 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
48	F53B6.5	F53B6.5	n/a	chrI 8,950,742	contains similarity to Pfam domain PF00557 metallopeptidase family M24 contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR011991 (Winged helix repressor DNA-binding)
49	W08F4.7	W08F4.7	n/a	chrII 576,333
50	D1014.7	D1014.7	n/a	chrV 8,119,293	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)