UCSC C. elegans Gene Sorter

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

UCSC C. elegans Gene Sorter

genome assembly search

sort by display output

#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	B0554.3	B0554.3	1e-25	chrV 434,275
2	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
3	nhr-172	C54F6.9	n/a	chrV 7,509,779	C. elegans NHR-172 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR015880 (Zinc finger, C2H2-like), IPR001781 (Zinc finger, LIM-type), IPR007087 (Zinc finger, C2H2-type)
4	ham-1	F53B2.6	n/a	chrIV 12,543,852	ham-1 encodes a novel protein with a winged helix DNA-binding motif; ham-1 is required for the asymmetric divisions of several neuroblasts in the developing embryo and may influence their spindle position; ham-1 mutations also exhibit HSN motor neuron migration defects; HAM-1 interacts with itself in a yeast two-hybrid screen and observations suggest that its multimerization is required for its proper localization; HAM-1 is cytoplasmic and is asymmetrically distributed to the posterior of the HSNPHB neuroblast.
5	F42C5.10	F42C5.10	n/a	chrIV 7,323,684	contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region)
6	F45E12.6	F45E12.6	n/a	chrII 7,313,979
7	K02A2.5	K02A2.5	n/a	chrII 7,411,491
8	src-2	F49B2.5	n/a	chrI 14,325,568	C. elegans SRC-2 protein; contains similarity to Pfam domains PF07653 (Variant SH3 domain) , PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00018 (SH3 domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR000719 (Protein kinase, core), IPR013315 (Spectrin alpha chain), IPR011511 (Variant SH3), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
9	srt-4	C29G2.4	n/a	chrV 2,578,859	C. elegans SRT-4 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
10	srh-7	K09D9.7	n/a	chrV 4,009,007	C. elegans SRH-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	F59C6.8	F59C6.8	n/a	chrI 10,511,155	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
12	C38C5.1	C38C5.1	n/a	chrX 5,560,137
13	ocr-2	T09A12.3	n/a	chrIV 8,216,912	ocr-2 encodes a TRPV (transient receptor potential channel, vanilloid subfamily) ion channel; OCR-2 activity is required for several types of sensory transduction including olfaction, osmosensation, mechanosensation, and chemosensation; an OCR-2 fusion protein is expressed in sensory cilia and requires the OSM-9 TRPV channel protein for proper localization; likewise, OSM-9 requires OCR-2 for its cilial localization.
14	ttx-3	C40H5.5	n/a	chrX 11,766,841	ttx-3 encodes a LIM homeodomain protein required for functions of the interneuron AIY, including thermosensory behavior and olfactory learning.
15	srw-10	ZC482.6	n/a	chrIII 12,755,860	C. elegans SRW-10 protein ;
16	srb-5	C27D6.6	n/a	chrII 5,162,671	C. elegans SRB-5 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
17	sri-45	K07E8.9	n/a	chrII 660,949	C. elegans SRI-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	lgc-1	T05B4.1	n/a	chrV 4,136,911	C. elegans LGC-1 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
19	F23B2.7	F23B2.7	n/a	chrIV 9,151,248	contains similarity to Homo sapiens similar to Cylicin I (Multiple-band polypeptide I); ENSEMBL:ENSP00000331556
20	W04A4.4	W04A4.4	n/a	chrI 13,676,809	contains similarity to Pfam domain PF00648 Calpain family cysteine protease contains similarity to Interpro domain IPR001300 (Peptidase C2, calpain)
21	Y57A10B.2	Y57A10B.2	n/a	chrII 12,376,431	contains similarity to Homo sapiens RNA binding protein; ENSEMBL:ENSP00000301740
22	elc-2	W03H1.2	n/a	chrX 1,777,746	elc-2 encodes a protein containing a Skp1 dimerisation domain that has homology to human transcription elongation factor B (SIII), polypeptide I (15kD, elonginsC).
23	T15B7.10	T15B7.10	n/a	chrV 6,811,130	contains similarity to Ostreococcus tauri Predicted CDS, putative cytoplasmic protein family member, with ascoiled coil-4 domain, of ancient origin (ISS).; TR:Q010X5
24	pha-2	M6.3	n/a	chrX 635,373	pha-2 encodes a homeodomain protein that is orthologous to vertebrate Hex proteins required for the development of B lymphocytes and organs derived from foregut endoderm; in C. elegans, pha-2 is essential for proper development and morphogenesis of the pm5 pharyngeal muscles cells during late stages of embryogenesis; in regulating pm5 fate specification, PHA-2 appears to act downstream of the organ identity factor PHA-4, and upstream of ceh-22, whose expression it may negatively regulate in pm5; a rescuing PHA-2::GFP reporter is expressed in pharyngeal cells, intestinal-rectal cells, and postembryonic head neurons.
25	nas-39	F38E9.2	n/a	chrX 16,464,603	C. elegans NAS-39 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) (2), PF00431 (CUB domain) (4), PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR015446 (Bone morphogenetic protein 1/tolloid-like protein), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR001506 (Peptidase M12A, astacin), IPR006210 (EGF), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013091 (EGF calcium-binding)
26	egrh-1	C27C12.2	n/a	chrX 14,847,486	C27C12.2 is orthologous to the human gene BA436D10.3 (EARLY GROWTH RESPONSE 2 (KROX-20 (DROSOPHILA) HOMOLOG)) (EGR2; OMIM:129010), which when mutated leads to disease.
27	F16G10.6	F16G10.6	n/a	chrII 2,377,526	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
28	clec-22	F49A5.3	n/a	chrV 16,859,205	C. elegans CLEC-22 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
29	F45E6.3	F45E6.3	n/a	chrX 12,488,021	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
30	C15H9.4	C15H9.4	n/a	chrX 6,103,253	contains similarity to Danio rerio Novel protein similar to human cerebral protein 11 (HUCEP11).; TR:Q1MTK0
31	C24A11.5	C24A11.5	n/a	chrI 5,385,191
32	C49F5.5	C49F5.5	n/a	chrX 11,986,477	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domain IPR000197 (Zinc finger, TAZ-type)
33	C45G3.4	C45G3.4	n/a	chrI 9,219,134	contains similarity to Dictyostelium discoideum Prespore-specific protein (Fragment).; TR:O97140
34	R04E5.7	R04E5.7	n/a	chrX 8,797,318
35	Y56A3A.5	Y56A3A.5	n/a	chrIII 11,889,625	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR000504 (RNA recognition motif, RNP-1)
36	math-32	F59H6.4	n/a	chrII 2,012,019	C. elegans MATH-32 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
37	srh-102	F40D4.11	n/a	chrV 17,164,173	C. elegans SRH-102 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	srg-39	T19C4.2	n/a	chrV 11,151,861	C. elegans SRG-39 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
39	F14H8.4	F14H8.4	n/a	chrV 15,024,402	contains similarity to Clostridium acetobutylicum Protein containing a domain related to multimeric flavodoxin WrbAsfamily.; TR:Q97H25
40	F31A9.1	F31A9.1	n/a	chrX 1,797,616
41	srd-5	T19E7.5	n/a	chrIV 5,673,565	C. elegans SRD-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR004268 (Virulence factor MVIN-like)
42	srb-17	F01D4.7	n/a	chrIV 10,455,510	C. elegans SRB-17 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
43	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	cyp-33C2	C45H4.17	n/a	chrV 2,185,028	C. elegans CYP-33C2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
45	sru-40	R07B5.3	n/a	chrV 9,833,347	C. elegans SRU-40 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
46	F54D12.8	F54D12.8	n/a	chrII 1,396,527	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR003609 (Apple-like)
47	T11F9.14	T11F9.14	n/a	chrV 11,480,742	contains similarity to Oryctolagus cuniculus Troponin I, fast skeletal muscle (Troponin I, fast-twitch isoform).; SW:TRIF_RABIT
48	acr-12	R01E6.4	n/a	chrX 13,534,608	acr-12 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8-like group of C. elegans nAChR subunits; as an nAChR subunit, ACR-12 is predicted to mediate fast excitatory neurotransmission, however loss of acr-12 activity via mutation or RNAi results in no obvious defects; ACR-12 copurifies with UNC-29 and LEV-1, suggesting that ACR-12 can form receptors with these two non-alpha AChR subunits; an ACR-12::GFP fusion protein is expressed exclusively in ventral cord motor neurons, including the D neurons; in vivo, ACR-12 colocalizes with some, but not all, UNC-38-containing postsynaptic receptor clusters, suggesting that ACR-12 contributes to only a subset of these receptor clusters.
49	glr-3	K10D3.1	n/a	chrI 7,119,675	glr-3 encodes a protein that contains a ligand-gated ion channel domain and a receptor family ligand binding domain with similarity to kainate-selective ionotropic glutamate receptor 2 (human GRIK2); expressed in the RIA neuron.
50	Y38H6C.9	Y38H6C.9	n/a	chrV 20,516,299	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)