UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srt-26	C24B9.2	6e-148	chrV 2,716,136	C. elegans SRT-26 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
2	clec-229	H02K04.1	n/a	chrV 15,340,763	C. elegans CLEC-229 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR001202 (WW/Rsp5/WWP)
3	F13A2.3	F13A2.3	n/a	chrV 4,394,967
4	unc-29	T08G11.5	n/a	chrI 8,899,525	unc-29 encodes an non-alpha subunit of the nicotinic acetylcholine receptor (nAChR) superfamily; UNC-29 is required for normal locomotion and egg-laying, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with LEV-1, a non-alpha nAChR subunit, and UNC-38 or UNC-63, alpha AChR subunits, the resulting multimer can form levamisole-gated channels; UNC-29 is expressed in body wall muscle.
5	dmd-4	C27C12.6	n/a	chrX 14,859,502	C. elegans DMD-4 protein; contains similarity to Pfam domains PF00751 (DM DNA binding domain) , PF03474 (DMRTA motif) contains similarity to Interpro domains IPR005173 (DMRTA motif), IPR001275 (DM DNA-binding)
6	aat-7	F54D12.3	n/a	chrII 1,389,233	aat-7 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-7 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-7 does not require this residue for heterodimer formation or alternatively, does not require the glycoprotein subunit for function.
7	snt-6	C08G5.4	n/a	chrII 747,906	C. elegans SNT-6 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
8	nhr-216	T09D3.4	n/a	chrV 5,356,451	C. elegans NHR-216 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
9	lgc-31	F21A3.7	n/a	chrV 15,516,308	C. elegans LGC-31 protein
10	F28B4.1	F28B4.1	n/a	chrX 3,205,615
11	T04B8.1	T04B8.1	n/a	chrII 635,951
12	W03F9.4	W03F9.4	n/a	chrV 149,461	contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domains IPR000542 (Acyltransferase ChoActase/COT/CPT), IPR001644 (C3A-anaphylatoxin receptor)
13	C44B11.1	C44B11.1	n/a	chrIII 3,156,820	contains similarity to Pfam domain PF06905 Fas apoptotic inhibitory molecule (FAIM1) contains similarity to Interpro domain IPR010695 (Fas apoptotic inhibitory molecule)
14	glb-11	C36E8.2	n/a	chrIII 3,990,752	glb-11 encodes a globin; glb-11 transcription is higher in L3 and dauers than in young adults; glb-11 has no obvious function in mass RNAi assays; glb-11 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background.
15	C16C10.9	C16C10.9	n/a	chrIII 4,156,357	contains similarity to Bacillus anthracis MutS2 family protein.; TR:Q81L40
16	flp-4	C18D1.3	n/a	chrII 10,054,913	C. elegans FLP-4 protein ;
17	ctbp-1	F49E10.5	n/a	chrX 5,867,998	tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.
18	F08G12.5	F08G12.5	n/a	chrX 11,309,490	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
19	srb-17	F01D4.7	n/a	chrIV 10,455,510	C. elegans SRB-17 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
20	srd-60	C13B7.3	n/a	chrV 2,420,332	C. elegans SRD-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	unc-75	C17D12.2	n/a	chrI 11,596,943	unc-75 encodes an RNA-binding protein with two N-terminal RNA recognition motifs (RRMs), a glutamine/asparagine-rich linker domain, and a third C-terminal RRM; UNC-75 is orthologous to mammalian CELF/BrunoL proteins that control pre-mRNA splicing; unc-75 is expressed in all neurons and in neurosecretory gland cells, and is required for normal modulation of GABA- and acetylcholine-mediated neurotransmission; UNC-75 protein is found with other RRM proteins in dynamic nuclear speckles, consistent with a role in alternative mRNA splicing; unc-75 mutations can be rescued in vivo by a human unc-75 transgene, but not by exc-7 or W02D3.11, indicating that UNC-75 acts on evolutionarily conserved but highly specific pre-mRNA substrates; both UNC-75 and EXC-7 are required in parallel for normal cholinergic neurotransmission.
22	dkf-1	W09C5.5	n/a	chrI 13,644,346	C. elegans DKF-1 protein; contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) (2)contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR001849 (Pleckstrin-like), IPR000719 (Protein kinase, core), IPR015727 (Protein kinase C mu-related), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
23	F02E11.3	F02E11.3	n/a	chrII 3,273,416	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
24	R04B3.1	R04B3.1	n/a	chrX 2,468,815	contains similarity to Interpro domain IPR000998 (MAM)
25	ZK896.1	ZK896.1	n/a	chrIV 12,874,056	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
26	C01B12.2	C01B12.2	n/a	chrII 20,848	contains similarity to Pfam domain PF01342 SAND domain contains similarity to Interpro domains IPR010919 (SAND-like), IPR000770 (SAND)
27	str-150	T03E6.4	n/a	chrV 16,584,195	C. elegans STR-150 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	C34E7.3	C34E7.3	n/a	chrX 12,931,101	contains similarity to Plasmodium falciparum Ribonuclease, putative.; TR:Q8ICL5
29	moe-3	F32A11.6	n/a	chrII 13,163,070	moe-3 encodes a CCCH tandem zinc finger (TZF) protein; while loss of moe-3 activity via RNAi alone results in no obvious abnormalities, animals triply mutant for moe-3, oma-1, and oma-2 demonstrate oocyte maturation defects, indicating that these genes likely function redundantly during germline development; in situ hybridization experiments indicate that moe-3 mRNA expression is relatively weak and restricted to the distal region of the gonad; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of MOE-3 is predicted to function as an RNA-binding protein.
30	asic-2	T28F4.2	n/a	chrI 7,481,759	C. elegans ASIC-2 protein; contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domains IPR001873 (Na+ channel, amiloride-sensitive), IPR004726 (Degenerin)
31	D1044.1	D1044.1	n/a	chrIII 5,545,251	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
32	T02H6.8	T02H6.8	n/a	chrII 681,180
33	str-39	F37B4.12	n/a	chrV 2,878,851	C. elegans STR-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002355 (Multicopper oxidase, copper-binding site)
34	CD4.5	CD4.5	n/a	chrV 5,590,729
35	F48B9.1	F48B9.1	n/a	chrX 2,183,370	contains similarity to Interpro domain IPR001220 (Legume lectin, beta domain)
36	php-3	Y75B8A.1	n/a	chrIII 12,075,804	C. elegans PHP-3 protein; contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
37	unc-130	C47G2.2	n/a	chrII 11,282,880	A member of the forkhead domain family of transcription factors that affects the generation of the AWA and ASG chemosensory neurons and is partially required for male tail morphogenesis and embryogenesis; it is expressed in the AWA and ASG precursors; it is required for the graded spatial expression of the UNC-129 TGF-beta guidance factor.
38	bbs-9	C48B6.8	n/a	chrI 6,920,270	C. elegans BBS-9 protein ; contains similarity to Homo sapiens 95 kDa protein; ENSEMBL:ENSP00000346214
39	Y56A3A.5	Y56A3A.5	n/a	chrIII 11,889,625	contains similarity to Pfam domain PF01425 Amidase contains similarity to Interpro domains IPR000120 (Amidase signature enzyme), IPR000504 (RNA recognition motif, RNP-1)
40	C46E10.5	C46E10.5	n/a	chrII 3,712,130
41	pqn-84	Y41C4A.5	n/a	chrIII 11,701,451	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
42	fax-1	F56E3.4	n/a	chrX 3,198,294	fax-1 encodes a conserved nuclear receptor that contains two C4-type zinc fingers and is orthologous to the vertebrate photoreceptor-specific nuclear receptor PNR (OMIM:604485, mutated in enhanced S-cone syndrome and retinitis pigmentosa); fax-1 is required for normal locomotion and neuron fate specification, including specification of the AVA, AVE, and AVK interneurons and proper axon pathfinding of the AVK, HSNL, and PVQL axons; expression of reporter gene fusions in fax-1 mutants suggests that fax-1 functions by regulating expression of a number of downstream targets, including nmr-1 and nmr-2, opt-3, flp-1, and ncs-1; in some neurons, fax-1 regulates expression combinatorially with unc-42, which encodes a paired-like homeodomain protein that additionally, regulates fax-1 expression in AVK neurons; FAX-1 is expressed in the nuclei of 18 neurons, including the AVK, AVA, AVB, and AVE interneurons, beginning at mid-embryogenesis and continuing through larval and adult stages; FAX-1 is also seen in two non-neuronal cell types: the distal tip cells (DTCs), from L2 to L4 larval stages, and two pairs of vulval cells in L4 animals.
43	sto-6	Y71H9A.2	n/a	chrX 11,634,381	C. elegans STO-6 protein; contains similarity to Pfam domain PF01145 SPFH domain / Band 7 family contains similarity to Interpro domains IPR001107 (Band 7 protein), IPR001972 (Stomatin)
44	Y18D10A.2	Y18D10A.2	n/a	chrI 12,808,033	contains similarity to Pfam domain PF03227 Gamma interferon inducible lysosomal thiol reductase (GILT) contains similarity to Interpro domain IPR004911 (Gamma interferon inducible lysosomal thiol reductase GILT)
45	lon-2	C39E6.1	n/a	chrX 4,743,993	lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans; during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length; genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling; in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells; LON-2 localizes to the cell surface.
46	T04F8.3	T04F8.3	n/a	chrX 11,658,991	contains similarity to Staphylococcus phage 44AHJD Hypothetical protein.; TR:Q859L9
47	str-31	C54F6.10	n/a	chrV 7,507,570	C. elegans STR-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000539 (Frizzled protein)
48	T05C12.8	T05C12.8	n/a	chrII 8,189,001	contains similarity to Interpro domain IPR002110 (Ankyrin)
49	F16C3.2	F16C3.2	n/a	chrI 10,152,680	contains similarity to Clostridium acetobutylicum DNA repair protein recN, ATPase.; TR:Q97HD9
50	lgc-34	T27A1.4	n/a	chrII 528,462	C. elegans LGC-34 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)