UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxa-58	C29F9.11	3e-178	chrIII 110,182	C. elegans FBXA-58 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
2	tre-4	F15A2.2	n/a	chrX 13,473,950	C. elegans TRE-4 protein; contains similarity to Pfam domain PF01204 Trehalase contains similarity to Interpro domains IPR001661 (Glycoside hydrolase, family 37), IPR000886 (Endoplasmic reticulum, targeting sequence), IPR008928 (Six-hairpin glycosidase-like)
3	F55A3.6	F55A3.6	n/a	chrI 10,784,384	contains similarity to Pfam domain PF00334 Nucleoside diphosphate kinase contains similarity to Interpro domain IPR001564 (Nucleoside diphosphate kinase, core)
4	F32B4.6	F32B4.6	n/a	chrI 11,516,108	contains similarity to Pfam domains PF07819 (PGAP1-like protein) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR012908 (PGAP1-like)
5	ZK1058.9	ZK1058.9	n/a	chrIII 3,924,612	contains similarity to Borrelia burgdorferi Probable O-sialoglycoprotein endopeptidase (EC 3.4.24.57)s(Glycoprotease).; SW:GCP_BORBU
6	col-110	F19C7.7	n/a	chrIV 4,608,935	C. elegans COL-110 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
7	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
8	F42E8.1	F42E8.1	n/a	chrV 13,063,254	contains similarity to Campylobacter jejuni DNA polymerase III alpha subunit (EC 2.7.7.7).; SW:DP3A_CAMJE
9	H34C03.2	H34C03.2	n/a	chrIV 6,759,933	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR006615 (Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)
10	T11G6.3	T11G6.3	n/a	chrIV 10,853,967	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
11	T19C9.8	T19C9.8	n/a	chrV 17,239,506	contains similarity to Amsacta moorei entomopoxvirus AMV141.; TR:Q9EMQ8
12	C26E1.2	C26E1.2	n/a	chrV 13,306,168	contains similarity to Interpro domain IPR000169 (Eukaryotic thiol (cysteine) protease)
13	H06O01.2	H06O01.2	n/a	chrI 7,012,174	H06O01.2 encodes a large (1,461-aa) putative chromodomain helicase DNA-binding protein that inhibits DHC-1 in vivo; H06O01.2 is orthologous to budding yeast CHD1, human CHD1 (OMIM:602118), and human CHD2 (OMIM:602119); H06O01.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that H06O01.2 negatively regulates dynein; H06O01.2 has no obvious function in mass RNAi assays.
14	H03A11.1	H03A11.1	n/a	chrX 15,211,201	H03A11.1 encodes an FAM20 ortholog; murine FAM20A is a secreted protein expressed in hematopoietic cells.
15	F55A12.6	F55A12.6	n/a	chrI 5,340,452	contains similarity to Interpro domain IPR002952 (Eggshell protein)
16	C26E1.3	C26E1.3	n/a	chrV 13,303,181	contains similarity to Interpro domains IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
17	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
18	nhr-247	ZK1037.5	n/a	chrV 15,324,578	C. elegans NHR-247 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	Y39A3A.2	Y39A3A.2	n/a	chrIII 2,057,188	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold)
20	ZC376.2	ZC376.2	n/a	chrV 14,173,463	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR002018 (Carboxylesterase, type B), IPR002000 (Lysosome-associated membrane glycoprotein (Lamp)/CD68)
21	W04C9.2	W04C9.2	n/a	chrI 489,263
22	T20H9.6	T20H9.6	n/a	chrIII 2,247,987	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
23	tre-1	F57B10.7	n/a	chrI 6,556,662	C. elegans TRE-1 protein; contains similarity to Pfam domain PF01204 Trehalase contains similarity to Interpro domains IPR001661 (Glycoside hydrolase, family 37), IPR008928 (Six-hairpin glycosidase-like)
24	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
25	C56C10.11	C56C10.11	n/a	chrII 6,599,683
26	sbp-1	Y47D3B.7	n/a	chrIII 11,435,265	sbp-1 encodes a basic helix-loop-helix (bHLH) transcription factor homologous to the mammalian Sterol Regulatory Element Binding Proteins (SREBPs, OMIM:184756, overexpression of nuclear form of SREBP-1c is associated with insulin resistance and features of congenital generalized lipodystrophy); in C. elegans, SBP-1 activity is required for normal lipid metabolism and wild-type levels of lipogenic enzyme expression, as well as for embryonic and larval development; sbp-1 expression is detected exclusively in the intestine, the major site of fat storage, from early embryogenesis through adulthood.
27	srv-29	T13A10.6	n/a	chrIV 6,265,730	C. elegans SRV-29 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
28	R09F10.1	R09F10.1	n/a	chrX 8,324,257	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
29	F53B6.5	F53B6.5	n/a	chrI 8,950,742	contains similarity to Pfam domain PF00557 metallopeptidase family M24 contains similarity to Interpro domains IPR000994 (Peptidase M24, catalytic core), IPR011991 (Winged helix repressor DNA-binding)
30	ZK328.6	ZK328.6	n/a	chrIII 6,029,645	contains similarity to Pfam domains PF02818 (PPAK motif) , PF00646 (F-box domain) contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
31	lbp-8	T22G5.6	n/a	chrV 13,891,011	lpb-8 belongs to a family of small intracellular fatty acid binding proteins (FABPs) that includes As-p18, found in the parasitic nematode Ascaris suum; lpb-8 shares 55% identity with bovine heart FABP but only 25% identity with As-p18 and lacks a secretory signal
32	C46G7.2	C46G7.2	n/a	chrIV 6,016,483	contains similarity to Anisakis simplex 29kDa protein from Anisakis simplex.; TR:Q9U5Z9
33	F15E11.2	F15E11.2	n/a	chrV 2,335,582	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
34	C49C3.5	C49C3.5	n/a	chrIV 17,329,906	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
35	math-8	C16C4.13	n/a	chrII 1,888,192	C. elegans MATH-8 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
36	ZC373.1	ZC373.1	n/a	chrX 10,055,836	The ZC373.1 gene encodes an ortholog of the human gene CYSTATHIONINE-BETA-SYNTHASE (CBS), which when mutated leads to homocystinuria (OMIM:236200).
37	maoc-1	E04F6.3	n/a	chrII 7,196,834	maoc-1 encodes an ortholog of human HSD17B4 (OMIM:601860, mutated in D-bifunctional protein deficiency); MAOC-1 contains a MaoC-like domain found in diverse enzymes (HSD17B4, peroxisomal hydratase-dehydrogenase-epimerase, and the fatty acid synthase beta subunit) and by homology, is predicted to function in peroxisomal fatty acid beta-oxidation; loss of maoc-1 activity via RNAi results in lifespan extension, increased fat content, and an increased susceptibility to pathogens.
38	gsp-1	F29F11.6	n/a	chrV 10,684,438	C. elegans GSP-1 protein; contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
39	T10E10.4	T10E10.4	n/a	chrX 6,318,637	T10E10.4 encodes a large (966-residue) protein, predicted to be secreted, with two N-terminal chitin-binding peritrophin-A domains followed by 14 cysteine-rich domains and one C-terminal EB module; the general organization of T10E10.4 protein resembles that of K04H4.2; T10E10.4 has no obvious function in mass RNAi assays but, like CEJ-1 and CPG-2, might participate in chitin synthesis.
40	pps-1	T14G10.1	n/a	chrIV 10,163,166	pps-1 is orthologous to human PAPSS1 (OMIM:603262) and human PAPSS2 (OMIM:603005, mutated in spondyloepimetaphyseal dysplasia).
41	F26E4.6	F26E4.6	n/a	chrI 9,773,519	contains similarity to Pfam domain PF02935 Cytochrome c oxidase subunit VIIc contains similarity to Interpro domain IPR004202 (Cytochrome c oxidase subunit VIIc)
42	pxn-1	ZK994.3	n/a	chrV 8,498,505	C. elegans PXN-1 protein; contains similarity to Pfam domains PF07686 (Immunoglobulin V-set domain) , PF00047 (Immunoglobulin domain) (2), PF00560 (Leucine Rich Repeat) (4), PF01462 (Leucine rich repeat N-terminal domain) , PF07679 (Immunoglobulin I-set domain) (2), PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR013098 (Immunoglobulin I-set), IPR010255 (Haem peroxidase), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR013106 (Immunoglobulin V-set), IPR007110 (Immunoglobulin-like), IPR002007 (Haem peroxidase, animal), IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
43	F56A12.2	F56A12.2	n/a	chrV 14,377,560	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
44	nhr-267	H22D14.1	n/a	chrIV 9,285,626	C. elegans NHR-267 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	dylt-1	F13G3.4	n/a	chrI 7,300,621	dylt-1 encodes a putative dynein light chain subunit that inhibits DHC-1 in vivo, but is otherwise dispensable for viability; DYLT-1 is paralogous to DYLT-3, and orthologous to human DYNLT1 and DYNLT3 (OMIM: 300302); dylt-1(RNAi) and dylt-1(ok417) both suppress the lethality of conditional dhc-1 mutations, and dylt-1(RNAi) suppresses dhc-1(or195) spindle length and cytokinesis defects as well, indicating that DYLT-1 negatively regulates dynein; in oocytes and early embryos, DYLT-1 is associated with nuclear envelopes and centrosomes, and with meiotic and mitotic spindle poles; like DHC-1 itself, DYLT-1 is strongly mislocalized to centrosomes in dhc-1(or195) animals shifted to nonpermissive temperature.
46	F01D5.3	F01D5.3	n/a	chrII 13,999,536	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR001368 (TNFR/CD27/30/40/95 cysteine-rich region), IPR003582 (Metridin-like ShK toxin)
47	mrp-3	E03G2.2	n/a	chrX 15,934,560	C. elegans MRP-3 protein; contains similarity to Pfam domains PF00664 (ABC transporter transmembrane region) (2), PF00005 (ABC transporter) (2)contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR011527 (ABC transporter, transmembrane region, type 1), IPR001140 (ABC transporter, transmembrane region), IPR003593 (AAA+ ATPase, core)
48	gbh-1	D2089.5	n/a	chrII 10,692,053	gbh-1 encodes a predicted ortholog of human hBBOX1; expressed in the intestine and in head and body muscles.
49	clec-66	F35C5.9	n/a	chrII 12,905,422	C. elegans CLEC-66 protein; contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
50	pmp-4	T02D1.5	n/a	chrIV 17,404,001	The pmp-4 gene encodes a homolog of human ALD, which when mutated leads to X-linked adrenoleukodystrophy (OMIM:300100).