UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C43F9.7	C43F9.7	2e-25	chrIV 10,593,293	contains similarity to Xanthomonas campestris Hypothetical protein XCC1495.; TR:Q8PAI8
2	F02D10.6	F02D10.6	n/a	chrX 13,450,586	contains similarity to Cryptophlebia leucotreta granulosis virus Hypothetical protein.; TR:Q7T5R9
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	pfd-6	F21C3.5	n/a	chrI 7,283,387	pfd-6 encodes a putative prefoldin 6 subunit, orthologous to human PFDN6 (OMIM:605660), required for normal microtubule growth and distal tip cell migration; PFD-6 is expressed cytoplasmically in most, if not all, tissues, including the germline; in mass RNAi assays, PFD-6 is required for normal mitotic spindle position, embryonic and larval viability, fertility, body shape, vulval development, and locomotion, and for normally rapid growth; pfd-6(RNAi) embryos show a reduced microtubule growth rate.
5	srw-22	T10H4.3	n/a	chrV 15,269,194	C. elegans SRW-22 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
6	sri-37	D2062.2	n/a	chrII 2,630,401	C. elegans SRI-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	C36C9.1	C36C9.1	n/a	chrX 1,684,665	contains similarity to Dictyostelium discoideum Similar to Homo sapiens (Human). Dentin sialophosphoprotein [Contains:sDentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentinssialoprotein (DSP)].; TR:Q869X8
8	F38H4.10	F38H4.10	n/a	chrIV 11,861,497	contains similarity to Pfam domain PF03637 Mob1/phocein family contains similarity to Interpro domain IPR005301 (Mob1/phocein)
9	sdz-36	ZK1251.7	n/a	chrIV 9,691,129	C. elegans SDZ-36 protein
10	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
11	srw-98	K04F1.3	n/a	chrV 1,677,402	C. elegans SRW-98 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
12	C29G2.1	C29G2.1	n/a	chrV 2,591,466
13	Y57G11C.25	Y57G11C.25	n/a	chrIV 14,919,983	Y57G11C.25 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y57G11C.25 is predicted to function as an RNA-binding protein.
14	hex-3	Y39A1C.4	n/a	chrIII 10,851,789	hex-3 encodes a beta-N-acetylhexosaminidase.
15	twk-44	Y71H9A.1	n/a	chrX 11,625,639	C. elegans TWK-44 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR011001 (Saposin-like), IPR008139 (Saposin B), IPR013099 (Ion transport 2)
16	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)
17	T10B5.8	T10B5.8	n/a	chrV 1,843,425	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal)
18	srx-111	T24E12.4	n/a	chrII 3,758,519	C. elegans SRX-111 protein ;
19	him-8	T07G12.12	n/a	chrIV 10,562,902	him-8 encodes a protein with two C-terminal noncanonical C2H2 zinc-fingers whose paralogs include ZIM-1/-3 and C02F5.12; HIM-8 is required by X chromosomes for normal homolog pairing, synapsis, recombination, and segregation during meiosis; him-8 mutants have an increased frequency of genotypically XO males in self-fertile hermaphrodite populations; HIM-8 is expressed during meiosis, and is associated with the X chromosome's meiotic pairing center (PC), which associates with the nuclear envelope during meiotic prophase; him-8 mutations are enhanced by rearrangements that inactivate the X-chromosomal PC; HIM-8 functions are genetically separable, since the him-8(me4) point mutation (which alters a domain N-terminal to HIM-8's zinc fingers) permits normal chromosome binding and nuclear localization, but causes abnormal pairing and synapsis; while the C-terminal region of HIM-8 most closely resembles those of its orthologs in other Caenorhabditis species, its N-terminal region is highly divergent, suggesting species-specific functions; unlike other him mutations, him-8 solely affects X chromosomes, and does not produce embryonic lethality via autosomal nondisjunction or aneuploidy; however, failure of X-chromosomal synapsis in him-8 mutants blocks the pachytene transistion from polarized to nonpolarized meiotic nuclei, by blocking the resolution of recombination intermediates on other chromosomes; him-8-blocked meiotic autosomes show persistent RAD-51 foci and have excess crossovers, both of which may be symptoms of a HUS-1-independent checkpoint induced by X-chromosomal nonsynapsis rather than DNA damage; HIM-8 also acts outside of meiosis, by inhibiting EGL-13 expression or activity; mutations of the HIM-8 zinc-finger domain semidominantly suppress missense (but not null) egl-13 mutations, due to him-8 haploinsufficiency; mutant HIM-8 fails to suppress mutant egl-13 on a free transgenic array, and also fails to suppress native mutant egl-13 if transgenic excess copies of the egl-13 promoter are present.
20	acr-14	T05C12.2	n/a	chrII 8,175,996	acr-14 encodes a protein that contains neurotransmitter-gated ion-channel ligand-binding and transmembrane domains.
21	fut-3	F59E12.13	n/a	chrII 5,658,783	C. elegans FUT-3 protein; contains similarity to Pfam domain PF00852 Glycosyltransferase family 10 (fucosyltransferase) contains similarity to Interpro domain IPR001503 (Glycosyl transferase, family 10)
22	R10E4.6	R10E4.6	n/a	chrIII 4,294,138
23	D1007.4	D1007.4	n/a	chrI 4,580,304	contains similarity to Homo sapiens Gem-associated protein 6; ENSEMBL:ENSP00000281950
24	glb-7	C23H5.2	n/a	chrIV 2,124,416	glb-7 encodes a globin with no obvious function in mass RNAi assays.
25	F54D10.9	F54D10.9	n/a	chrII 3,830,742	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
26	D1054.3	D1054.3	n/a	chrV 10,772,116	contains similarity to Pfam domains PF04969 (CS domain) , PF05002 (SGS domain) contains similarity to Interpro domains IPR007699 (SGS), IPR008978 (HSP20-like chaperone), IPR017447 (CS), IPR007052 (CS domain)
27	C34E10.8	C34E10.8	n/a	chrIII 5,251,598	contains similarity to Leishmania major strain Friedlin Proteophosphoglycan 5.; TR:Q4FX62
28	T24E12.2	T24E12.2	n/a	chrII 3,783,547
29	R07E4.5	R07E4.5	n/a	chrX 5,951,318	contains similarity to Plasmodium lophurae Histidine-rich glycoprotein precursor.; SW:P04929
30	clec-223	C03E10.5	n/a	chrV 11,275,618	C. elegans CLEC-223 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR008160 (Collagen triple helix repeat)
31	B0281.4	B0281.4	n/a	chrII 2,298,366	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
32	srj-8	T28A11.9	n/a	chrV 3,248,476	C. elegans SRJ-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	sri-12	T22H2.1	n/a	chrI 11,700,163	C. elegans SRI-12 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	T09B4.1	T09B4.1	n/a	chrI 6,186,762	contains similarity to Pfam domain PF04188 Mannosyltransferase (PIG-V)) contains similarity to Interpro domain IPR007315 (Mannosyltransferase, PIG-V)
35	T09B4.2	T09B4.2	n/a	chrI 6,184,694
36	W06D11.5	W06D11.5	n/a	chrX 12,300,631	contains similarity to Homo sapiens Hypothetical protein KIAA1801; ENSEMBL:ENSP00000256007
37	srx-22	F31F4.3	n/a	chrV 680,688	C. elegans SRX-22 protein ;
38	str-19	T23D5.7	n/a	chrV 15,743,832	C. elegans STR-19 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	R09A8.2	R09A8.2	n/a	chrX 12,621,311	contains similarity to Staphylococcus aureus Serine-rich adhesin for platelets precursor (Staphylococcus aureusssurface protein A).; SW:Q8NUJ3
40	F56H6.4	F56H6.4	n/a	chrI 12,291,320	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
41	mec-14	F37C12.12	n/a	chrIII 7,191,528	mec-14 encodes a protein with similarity to the beta-subunits of Shaker-type potassium channels, which are members of the aldo-keto reductase superfamily; MEC-14 is required for response to gentle touch by the six touch receptor neurons, and likely functions to regulate activity of the MEC-4 and MEC-10 degenerin channels; mec-14 expression is detected solely in the touch receptor neurons and is dependent on the MEC-3 LIM domain transcription factor; proper MEC-14 localization in the touch receptor neurons is dependent on MEC-12/alpha-tubulin.
42	srh-141	T08G3.5	n/a	chrV 16,444,803	C. elegans SRH-141 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	ZK177.9	ZK177.9	n/a	chrII 5,517,477
44	srw-142	H05B21.3	n/a	chrV 2,957,658	C. elegans SRW-142 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
45	F31B9.3	F31B9.3	n/a	chrX 15,924,034	contains similarity to Homo sapiens Similar to polymerase (RNA) III; ENSEMBL:ENSP00000334758
46	T05E7.3	T05E7.3	n/a	chrI 6,190,389	contains similarity to Interpro domain IPR000463 (Cytosolic fatty-acid binding)
47	F59A6.5	F59A6.5	n/a	chrII 5,001,644	contains similarity to Pfam domains PF00169 (PH domain) , PF00780 (CNH domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR000533 (Tropomyosin), IPR001180 (Citron-like), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
48	Y39A1A.16	Y39A1A.16	n/a	chrIII 10,680,725	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
49	T08G5.1	T08G5.1	n/a	chrV 14,019,744	contains similarity to Saccharomyces cerevisiae Protein that may function as a cochaperone, as suggested by the presence of a DnaJ-like domain; SGD:YNL227C
50	cyn-12	C34D4.12	n/a	chrIV 7,132,656	cyn-12 encodes a member of the cyclophilin family that is related to human PPIL1 (CGI-124); based upon its sequence similarity, CYN-12 is predicted to be a cytoplasmic protein potentially involved in a wide range of signal transduction pathways.