UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C44H4.1	C44H4.1	0	chrX 14,574,334	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
2	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	ZC449.1	ZC449.1	n/a	chrX 5,026,248	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR000169 (Peptidase, cysteine peptidase active site)
5	C27F2.8	C27F2.8	n/a	chrIII 4,994,766	contains similarity to Interpro domain IPR000694 (Proline-rich region)
6	W05B2.2	W05B2.2	n/a	chrIII 10,963,526	contains similarity to Pfam domains PF01683 (EB module) (2), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (6)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat), IPR006149 (Nematode-specific EB region)
7	ltd-1	K02C4.4	n/a	chrII 8,090,520	ltd-1 encodes a protein with LIM and transglutaminase domains; LTD-1 is homologous to the mouse KY protein (MGI:96709, mutated in kyphoscoliosis), and to the HILLARIN protein of Hirudo medicinalis, found at axon hillocks; ltd-1 is expressed in hypodermal cells from the twofold stage embryo to adulthood, but has no obvious function in mass RNAi assays.
8	F35D2.2	F35D2.2	n/a	chrII 7,575,045
9	ptr-9	F54G8.5	n/a	chrIII 9,159,358	ptr-9 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTR-9 is required for normal development in mass RNAi assays.
10	acr-2	K11G12.2	n/a	chrX 6,705,942	A homolog of a non-alpha type nicotinic acetylcholine receptor subunit that forms a functional channel when co-expressed with the unc-38 alpha subunit.
11	T23C6.5	T23C6.5	n/a	chrX 17,156,542	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR004827 (Basic-leucine zipper (bZIP) transcription factor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
12	Y38H6C.16	Y38H6C.16	n/a	chrV 20,532,568	contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
13	set-30	ZC8.3	n/a	chrX 5,001,358	set-30 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-30 is paralogous to SET-10, SET-14, and SET-18; neither set-30(gk314) nor set-30(RNAi) have any obvious phenotypes.
14	clec-263	F26F2.6	n/a	chrV 20,571,518	C. elegans CLEC-263 protein; contains similarity to Pfam domains PF08277 (PAN-like domain) (2), PF00024 (PAN domain) contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
15	C34D4.14	C34D4.14	n/a	chrIV 7,139,438	contains similarity to Pfam domains PF06701 (Mib_herc2) , PF07738 (Sad1 / UNC-like C-terminal) , PF02985 (HEAT repeat) , PF00023 (Ankyrin repeat) (2), PF00632 (HECT-domain (ubiquitin-transferase)) contains similarity to Interpro domains IPR012919 (Sad1/UNC-like, C-terminal), IPR011989 (Armadillo-like helical), IPR000569 (HECT), IPR008979 (Galactose-binding like), IPR002110 (Ankyrin), IPR010606 (Mib-herc2), IPR016024 (Armadillo-type fold)
16	K09B3.1	K09B3.1	n/a	chrIV 3,795,512	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
17	ZK265.8	ZK265.8	n/a	chrI 8,271,989	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
18	F41C3.11	F41C3.11	n/a	chrII 4,732,558	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domains IPR002345 (Lipocalin), IPR005069 (Protein of unknown function DUF271)
19	fbxa-209	Y36E3A.1	n/a	chrV 15,424,620	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
20	F07E5.7	F07E5.7	n/a	chrII 2,071,109	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
21	col-75	K03H9.2	n/a	chrII 6,426,809	C. elegans COL-75 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
22	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
23	R07B1.5	R07B1.5	n/a	chrX 9,865,660	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
24	srr-1	W07G4.6	n/a	chrV 13,051,818	C. elegans SRR-1 protein; contains similarity to Pfam domain PF03268 Caenorhabditis protein of unknown function, DUF267 contains similarity to Interpro domain IPR004950 (Protein of unknown function DUF267, Caenorhabditis species)
25	dpy-28	Y39A1B.3	n/a	chrIII 10,770,127	dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1.
26	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
27	unc-7	R07D5.1	n/a	chrX 15,134,407	unc-7 encodes an innexin required for gap junction formation in invertebrates; UNC-7 is also required for normal locomotion, egg-laying, inhibition of feeding by tapping, avermectin sensitivity, and ivermectin sensitivity, as well as for the antagonism of UNC-79 and UNC-80 activity by volatile anesthetics; unc-7 is genetically required, and transcribed in, neurons rather than muscle cells, from larval stages L1 through L4; homologs of UNC-7 include Drosophila OGRE and SHAKING-B, as well as 24 C. elegans paralogs (including EAT-5, UNC-9, and INX-1 through INX-20); UNC-7 genetically interacts with UNC-124, and unc-7 mutants are phenotypically similar to unc-9 and unc-124 mutants; UNC-7 genetically interacts with AVR-14 and GLC-1 in the response to ivermectin.
28	fbxa-154	B0391.6	n/a	chrV 15,603,958	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
29	ugt-59	R11A8.3	n/a	chrIV 10,362,030	C. elegans UGT-59 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
30	Y57G7A.1	Y57G7A.1	n/a	chrII 1,299,102
31	ttr-11	F46B3.3	n/a	chrV 20,599,260	C. elegans TTR-11 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
32	abch-1	C56E6.5	n/a	chrII 6,530,223	C. elegans ABCH-1 protein; contains similarity to Interpro domain IPR003439 (ABC transporter-like)
33	F14H12.2	F14H12.2	n/a	chrX 4,351,596
34	srh-223	F47C12.3	n/a	chrIV 3,982,749	C. elegans SRH-223 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	rhgf-1	F13E6.6	n/a	chrX 10,704,787	rhgf-1 encodes an RGS RhoGEF (Regulator of G-protein Signaling Rho Guanine Nucleotide Exchange Factor); RHGF-1 functions within cholingergic motor neurons in one of four G-protein-mediated signaling pathways that control locomotion via regulation of acetylcholine (ACh) release at neuromuscular junctions; in regulating ACh release, RHGF-1 functions downstream of the C. elegans Galpha12 ortholog, GPA-12, and upstream of the Rho GTPase ortholog, RHO-1; additionally, rhgf-1 activity is required for normal mechanosensory behavior, egg laying, and embryonic development; an rhgf-1 reporter fusion is expressed in ventral cord motor neurons as well as several head neurons.
36	rsr-1	F28D9.1	n/a	chrI 11,179,945	C. elegans RSR-1 protein; contains similarity to Pfam domain PF01480 PWI domain contains similarity to Interpro domains IPR002483 (Splicing factor PWI), IPR000694 (Proline-rich region), IPR005819 (Histone H5), IPR002185 (Dopamine D4 receptor)
37	nmr-2	T01C3.10	n/a	chrV 15,009,000	C. elegans NMR-2 protein ;
38	T03D8.7	T03D8.7	n/a	chrV 20,811,735	contains similarity to Homo sapiens Uncharacterized protein ENSP00000381489; ENSEMBL:ENSP00000335483
39	ceh-10	W03A3.1	n/a	chrIII 5,800,012	ceh-10 encodes a member of the Paired-like class of homeodomain proteins; the CEH-10 homeodomain is closely related to the homeodomains of two vertebrate retina proteins (Chx10 from mice and Vsx-1 from goldfish); ceh-10 is required for CAN cell fate specification and migration, complete loss of ceh-10 function results in failure of CAN cell migration and loss of expression of CEH-23 and CEH-10 itself in the CAN and AIY interneurons; CEH-10, along with TTX-3 and CEH-23, constitutes a regulatory cascade of transcription factors that controls all sub-type specific features of the AIY interneurons.
40	B0331.2	B0331.2	n/a	chrV 9,660,245	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domain IPR001204 (Phosphate transporter)
41	F38B6.1	F38B6.1	n/a	chrX 6,700,523
42	R09A1.3	R09A1.3	n/a	chrV 1,025,455
43	gcy-33	F57F5.2	n/a	chrV 11,998,799	gcy-33 encodes a soluble guanylyl cyclase; a gcy-33::GFP reporter is expressed in the ciliated BAG head sensory neurons.
44	srg-67	ZC317.4	n/a	chrV 5,462,245	C. elegans SRG-67 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
45	K05C4.8	K05C4.8	n/a	chrI 14,732,974	contains similarity to Dictyostelium discoideum Sterol glucosyltransferase (EC 2.4.1.173).; TR:Q9XYD4
46	sri-74	F33H12.4	n/a	chrII 2,581,954	C. elegans SRI-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000576 (Proton/sugar symporter, LacY)
47	srh-28	ZC404.5	n/a	chrV 6,774,975	C. elegans SRH-28 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	agr-1	F41G3.12	n/a	chrII 6,767,868	agr-1 encodes a large (1396-residue) putative agrin, orthologous to human AGRIN (OMIM:103320), EGFLAM, and Q9NQ15; AGR-1 is expressed in buccal epithelium and deposited in pharyngeal basal epithelium; AGR-1 is also expressed in IL1 neurons, distal tip cells, and intestine; an AGR-1 fragment can cluster vertebrate dystroglycan in cell culture; agr-1(eg1770) mutations show no obvious phenotype, including levimasole resistance, and do not enhance other mutations perturbing acetylcholine signalling, the dystrophin-glycoprotein-complex, muscle cell differentiation, or the extracellular matrix.
49	tbb-4	B0272.1	n/a	chrX 9,435,612	C. elegans TBB-4 protein; contains similarity to Pfam domains PF00091 (Tubulin/FtsZ family, GTPase domain) , PF03953 (Tubulin/FtsZ family, C-terminal domain) contains similarity to Interpro domains IPR002454 (Gamma tubulin), IPR002452 (Alpha tubulin), IPR002453 (Beta tubulin), IPR000158 (Cell division protein FtsZ, N-terminal), IPR000217 (Tubulin), IPR003008 (Tubulin/FtsZ, GTPase), IPR008280 (Tubulin/FtsZ, C-terminal), IPR013838 (Beta tubulin, autoregulation binding site), IPR004057 (Epsilon tubulin), IPR002967 (Delta tubulin)
50	zag-1	F28F9.1	n/a	chrIV 3,858,673	zag-1 encodes a homeodomain protein of the ZFH class which consists of a homeodomain flanked by two clusters of C2H2-type zinc fingers and is related to transcriptional repressors encoded by Drosophila zfh-1 and the vertebrate ZEB genes; ZAG-1 is required for locomotion, for neuronal differentiation, and for proper axonal branching and fasciculation; from late embryogenesis through adult stages of development, ZAG-1 is expressed dynamically in head and tail neurons and in the intestinal and anal depressor muscles.