UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C46A5.2	C46A5.2	0	chrIV 7,761,432	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	Y44E3A.4	Y44E3A.4	n/a	chrI 3,325,798	contains similarity to Pfam domains PF07653 (Variant SH3 domain) (2), PF00018 (SH3 domain) (2)contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR000694 (Proline-rich region), IPR011511 (Variant SH3), IPR003071 (Orphan nuclear receptor, HMR type)
4	pqn-27	E01G4.4	n/a	chrII 13,454,655	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
5	C11D9.1	C11D9.1	n/a	chrI 4,424,085	contains similarity to Pfam domain PF00621 RhoGEF domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001478 (PDZ/DHR/GLGF)
6	Y51H1A.2	Y51H1A.2	n/a	chrII 13,867,372	contains similarity to Pfam domain PF02759 RUN domain contains similarity to Interpro domain IPR004012 (RUN)
7	mrt-2	Y41C4A.14	n/a	chrIII 11,748,489	mrt-2 encodes a highly conserved DNA-damage checkpoint protein homologous to the RAD1 protein found in S. pombe, Drosophila, and mammals; MRT-2 interacts with HUS-1 and HPR-9, also conserved DNA-damage checkpoint proteins, and is required in the germline for maintaining chromosomal integrity; mrt-2 mutations result in a failure to induce apoptosis in response to DNA damage, progressive telomere loss, chromosome fusion, and aneuploidy, all leading eventually to germline immortality.
8	C06E1.9	C06E1.9	n/a	chrIII 8,608,051	contains similarity to Interpro domain IPR001680 (WD40 repeat)
9	R02E12.4	R02E12.4	n/a	chrX 4,005,562	contains similarity to Pfam domains PF03148 (Tektin family) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000435 (Tektin), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
10	K08F4.5	K08F4.5	n/a	chrIV 10,135,380	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_96, whole genome shotgun sequence.; TR:A0EH68
11	F28B1.3	F28B1.3	n/a	chrV 17,053,645	contains similarity to Interpro domain IPR009021 ()
12	ZC190.7	ZC190.7	n/a	chrV 8,686,461
13	clec-187	ZK896.6	n/a	chrIV 12,870,360	C. elegans CLEC-187 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
14	C34C6.2	C34C6.2	n/a	chrII 8,681,696	contains similarity to Homo sapiens KIAA1219; ENSEMBL:ENSP00000302059
15	T07D3.3	T07D3.3	n/a	chrII 895,627	contains similarity to Homo sapiens CGI16-iso; ENSEMBL:ENSP00000368599
16	nhr-166	C49D10.2	n/a	chrII 3,881,165	C. elegans NHR-166 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
17	Y48B6A.1	Y48B6A.1	n/a	chrII 14,152,681	Y48B6A.1 encodes an ortholog of human BOP1 (OMIM:610596, overexpressed in colon cancer) and S. cerevisiae ERB1; Y48B6A.1 may suppress tumorous growth in the germline; like PRO-1, -2, and -3, Y48B6A.1 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline; however, BOP1 is also a phosphoprotein in mitotic spindles and required for normal chromosomal segregation, raising the possibility that Y48B6A.1 is multifunctional.
18	atgp-2	C38C6.2	n/a	chrII 14,641,992	atgp-2 encodes an amino acid transporter glycoprotein subunit; when co-expressed in Xenopus oocytes with either the AAT-1 or AAT-3 catalytic subunit, ATGP-2 facilitates amino acid uptake and exchange, showing a relatively high affinity for small and some large neutral amino acids; when co-expressed with AAT-9, ATGP-2 is able to enhance the activity of this catalytic subunit; ATGP-2 can covalently associate with AAT-1 or AAT-3 in the Xenopus expression system; when co-expressed with AAT-1 or AAT-3, ATGP-2 localizes to the cell surface of oocytes, but when expressed alone, ATGP-2 localizes intracellularly.
19	M02F4.1	M02F4.1	n/a	chrX 3,028,999	contains similarity to Homo sapiens Isoform 1 of Splicing factor, arginine/serine-rich 12; ENSEMBL:ENSP00000284041
20	srg-25	T09D3.5	n/a	chrV 5,343,042	C. elegans SRG-25 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
21	clec-218	W02D7.2	n/a	chrV 8,309,344	C. elegans CLEC-218 protein; contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
22	tra-3	LLC1.1	n/a	chrIV 14,440,241	tra-3 encodes an atypical calpain regulatory protease that lacks calcium-binding EF hand domains; during development, TRA-3 likely promotes female development in XX hermaphrodites by cleaving the membrane-associated TRA-2A protein to generate a TRA-2 peptide likely to have feminizing activity; in addition, TRA-3 is one of several proteases that mediate necrotic cell death during neurodegeneration.
23	EGAP9.3	EGAP9.3	n/a	chrV 6,579,135	contains similarity to Pfam domain PF01531 Glycosyl transferase family 11 contains similarity to Interpro domain IPR002516 (Glycosyl transferase, family 11)
24	srd-43	R04D3.9	n/a	chrX 13,304,796	C. elegans SRD-43 protein ;
25	T07D3.6	T07D3.6	n/a	chrII 881,565	contains similarity to Pfam domain PF06828 Fukutin-related contains similarity to Interpro domain IPR009644 (Fukutin-related)
26	thoc-1	T02H6.2	n/a	chrII 705,367	C. elegans THOC-1 protein ; contains similarity to Danio rerio THO complex 1.; TR:Q7SYB2
27	del-2	F58G6.6	n/a	chrIV 9,639,468	del-2 encodes an unfamiliar protein whose promoter drives expression in IL1, ASH, and OLQ.
28	Y45F10D.6	Y45F10D.6	n/a	chrIV 13,797,043
29	srt-1	C13B7.1	n/a	chrV 2,436,754	C. elegans SRT-1 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
30	Y32B12B.1	Y32B12B.1	n/a	chrV 16,536,916	contains similarity to Leptospira kirschneri serovar grippotyphosa Hypothetical protein.; TR:Q8KWV2
31	Y47H9C.2	Y47H9C.2	n/a	chrI 11,842,812	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domain IPR001594 (Zinc finger, DHHC-type)
32	T27F6.6	T27F6.6	n/a	chrI 12,492,740	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domain IPR005135 (Endonuclease/exonuclease/phosphatase)
33	F34H10.2	F34H10.2	n/a	chrX 9,630,584	contains similarity to Anabaena sp Hypothetical protein Alr0331.; TR:Q8YZX4
34	T22F7.1	T22F7.1	n/a	chrIII 544,286	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR006655 (Molybdopterin oxidoreductase, prokaryotic, conserved site), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
35	Y4C6B.6	Y4C6B.6	n/a	chrIV 5,347,749	The Y4C6B.6 gene encodes a homolog of the human gene GLCM, which when mutated leads to Gaucher disease type I (OMIM:230800).
36	T14B4.2	T14B4.2	n/a	chrII 6,736,402	contains similarity to Pfam domain PF01084 Ribosomal protein S18 contains similarity to Interpro domain IPR001648 (Ribosomal protein S18)
37	nhr-125	R02D1.1	n/a	chrV 4,322,934	C. elegans NHR-125 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
38	F41G3.2	F41G3.2	n/a	chrII 6,759,863
39	Y39F10C.1	Y39F10C.1	n/a	chrII 675,733	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
40	F23B2.8	F23B2.8	n/a	chrIV 9,152,242	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
41	F53G12.3	F53G12.3	n/a	chrI 141,205	F53G12.3 encodes a large partial homolog of dual oxidase ('Ce-Duox2'), with an N-terminal peroxidase domain, two central calmodulin-binding EF hands, and a C-terminal superoxide-generating NADPH-oxidase domain; F53G12.3 may be required for dityrosine cross-linking of collagen, and thus for cuticular integrity; F53G12.3 may use cytosolic NADPH to generate reactive oxygen, which then may drive the peroxidase ectodomain to cross-link free tyrosine in collagen; F53G12.3 has no visible expression pattern detectable by antibodies, implying very low or rare expression.
42	T01C3.2	T01C3.2	n/a	chrV 14,991,380	T01C3.2 encodes a divergent ortholog of Drosophila melanogaster E(Y)2 and budding yeast Sus1p; by orthology, T01C3.2 is predicted to enable both transcriptional activation and silencing in chromatin; however, T01C3.2 has no obvious function in mass RNAi assays.
43	W02A11.1	W02A11.1	n/a	chrI 12,731,353	contains similarity to Pfam domain PF08704 tRNA methyltransferase complex GCD14 subunit contains similarity to Interpro domain IPR014816 (tRNA methyltransferase complex GCD14 subunit)
44	ZK596.3	ZK596.3	n/a	chrIV 10,903,190	contains similarity to Mus musculus DNA-dependent protein kinase catalytic subunit (EC 2.7.1.37) (DNA-sPKcs) (P460).; SW:PRKD_MOUSE
45	rnf-1	C06A5.9	n/a	chrI 6,010,654	C. elegans RNF-1 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
46	nhr-250	ZK488.1	n/a	chrV 613,820	C. elegans NHR-250 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
47	fbxa-200	T07D3.1	n/a	chrII 905,248	C. elegans FBXA-200 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
48	Y43F8B.11	Y43F8B.11	n/a	chrV 19,471,547	contains similarity to Campylobacter coli CadF precursor (Outer membrane protein).; TR:O06895
49	M142.5	M142.5	n/a	chrIII 10,931,599	contains similarity to Homo sapiens Isoform 1 of Protein LSM12 homolog; ENSEMBL:ENSP00000293406
50	T14B4.9	T14B4.9	n/a	chrII 6,731,934	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)