UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cyp-35A4	C49G7.8	0	chrV 4,032,492	C. elegans CYP-35A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
2	C48B4.1	C48B4.1	n/a	chrIII 9,589,349	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
3	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
4	E02H9.5	E02H9.5	n/a	chrIII 2,447,417	E02H9.5 encodes a homolog of the human beta-glucosidase-like proteins KL (klotho; OMIM:604824), KLB (beta-klotho; OMIM:611135), GBA3 (cytosolic beta-glucosidase; OMIM:606619), LCT (lactase-phlorizin hydrolase; OMIM:603202, variant in adult lactose tolerance), and LCTL (lactase-like protein); E02H9.5 has 76% identity (364/478 residues) to its paralog C50F7.10; perhaps due to genetic redundancy, E02H9.5 has no obvious function in mass RNAi assays.
5	npp-15	C29E4.4	n/a	chrIII 7,930,950	C. elegans NPP-15 protein; contains similarity to Pfam domains PF08801 (Nup133 N terminal like) , PF04044 (Nup133 nucleoporin) contains similarity to Interpro domains IPR014908 (Nup133, N-terminal), IPR015943 (WD40/YVTN repeat-like), IPR007187 (Nucleoporin, Nup133-like, C-terminal)
6	ugt-47	R04B5.9	n/a	chrV 10,097,423	C. elegans UGT-47 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
7	xpo-3	C49H3.10	n/a	chrIV 7,920,396	imb-6 encodes an importin-beta-like protein orthologous to vertebrate Exportin-t, a specific mediator of tRNA export from the nucleus; IMB-6 is predicted to function by binding tRNAs directly in the presence of the RAN-1 GTPase and facilitating their nucleocytoplasmic transport; in C. elegans, loss of imb-6 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities.
8	cyp-35A1	C03G6.14	8e-178	chrV 7,360,867	C. elegans CYP-35A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR001756 (ATPase, P-type copper-transporter)
9	K06A4.5	K06A4.5	n/a	chrV 9,506,309	contains similarity to Pfam domain PF06052 3-hydroxyanthranilic acid dioxygenase contains similarity to Interpro domains IPR011051 (Cupin, RmlC-type), IPR016700 (3-hydroxyanthranilate 3, 4-dioxygenase, metazoan), IPR010329 (3-hydroxyanthranilic acid dioxygenase)
10	T25D3.2	T25D3.2	n/a	chrII 155,462	contains similarity to Mus musculus 39S ribosomal protein L28, mitochondrial precursor (L28mt) (MRP-L28).; SW:Q9D1B9
11	C23H4.3	C23H4.3	n/a	chrX 12,227,955	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
12	cln-3.1	F07B10.1	n/a	chrV 11,264,600	cln-3.1 encodes a predicted transmembrane protein that comprises one of three C. elegans homologs of human CLN3, (OMIM:607042, mutations are associated with Batten disease (also known as juvenile neuronal ceroid lipofuscinosis), a recessively inherited childhood neurodegenerative lysosomal storage disease); as loss of cln-3.1 activity via deletion mutation results in no obvious abnormalities, the precise role of cln-3.1 in C. elegans development and/or behavior is not yet known.
13	R07E3.4	R07E3.4	n/a	chrX 10,331,226	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
14	nrf-6	C08B11.4	n/a	chrII 8,030,762	nrf-6 encodes a protein with 12 predicted transmembrane domains that is highly similar to NDG-4 and affects embryonic viability, yolk transport, locomotion, body morphology, and affects sensitivity to fluoxetine with respect to nose-contraction response in a common pathway with ndg-4 and nrf-5; expressed in the most anterior cells of the hypodermis and in the intestine and is required in the intestine for fluoxetine-induced nose contraction and yolk transport
15	C05D11.1	C05D11.1	n/a	chrIII 6,438,225	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
16	F20G2.2	F20G2.2	n/a	chrV 13,755,695	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
17	ugt-22	C08F11.8	n/a	chrIV 13,641,793	C. elegans UGT-22 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
18	R11A8.5	R11A8.5	n/a	chrIV 10,367,036	contains similarity to Pfam domains PF00462 (Glutaredoxin) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR011767 (Glutaredoxin active site), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
19	T04A8.6	T04A8.6	n/a	chrIII 4,692,695	T04A8.6 encodes an ortholog of S. cerevisiae NOP15 that may suppress tumorous growth in the germline; like PRO-1, -2, and -3, T04A8.6 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline.
20	B0035.15	B0035.15	n/a	chrIV 11,297,591	contains similarity to Saccharomyces cerevisiae Mlp proteins restrict telomere length by influencing the Rif1-Tel1 pathway of telomerase regulation; also involved in the translocation of macromolecules between the nucleoplasm and the NPC; SGD:YKR095W
21	lec-9	C16H3.2	n/a	chrX 17,600,900	lec-9 encodes a predicted lectin that affects embryonic viability.
22	lap-1	ZK353.6	n/a	chrIII 8,400,522	The lap-1 gene encodes a homolog of the zinc metalloprotease leucine aminopeptidase LAP that is predicted to be mitochondrial.
23	folt-2	F37B4.7	n/a	chrV 2,874,024	folt-2 encodes a putative folate transporter; FOLT-2 is orthologous to human SLC19A1 (OMIM:600424), SLC19A2 (OMIM:603941, mutated in thiamine-responsive megaloblastic anemia syndrome), and SLC19A3 (OMIM:606152, mutated in biotin-responsive basal ganglia disease); heterologously expressed FOLT-2 does not significantly transport folate; FOLT-2 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with its paralogs FOLT-1 and FOLT-3.
24	gex-3	F28D1.10	n/a	chrIV 12,406,527	The gex-3 gene encodes a homolog of NAP1/NCKAP1, a mammalian protein ligand of the small GTPase Rac1, and of Drosophila HEM2/NAP1/KETTE; gex-3 is required for tissue morphogenesis and cell migrations; in gex-3 mutants, cells differentiate properly but fail to become organized.
25	tin-13	DY3.1	n/a	chrI 8,759,490	C. elegans TIN-13 protein; contains similarity to Pfam domain PF02953 Tim10/DDP family zinc finger contains similarity to Interpro domain IPR004217 (Zinc finger, Tim10/DDP-type)
26	F25G6.8	F25G6.8	n/a	chrV 8,564,846	contains similarity to Pfam domain PF02290 Signal recognition particle 14kD protein contains similarity to Interpro domains IPR009018 (Signal recognition particle, SRP9/SRP14 subunit), IPR003210 (Signal recognition particle, SRP14 subunit)
27	T06E6.1	T06E6.1	n/a	chrV 15,394,012	contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
28	M88.2	M88.2	n/a	chrIII 4,541,915	contains similarity to Aedes aegypti Mitochondrial ribosomal protein, S34, putative.; TR:Q17JQ1
29	pfn-2	F35C8.6	n/a	chrX 5,353,590	C. elegans PFN-2 protein; contains similarity to Pfam domain PF00235 Profilin contains similarity to Interpro domains IPR002097 (Profilin/allergen), IPR005455 (Profilin, plant)
30	B0024.11	B0024.11	n/a	chrV 10,318,482	contains similarity to Pfam domain PF01142 tRNA pseudouridine synthase D (TruD) contains similarity to Interpro domains IPR001656 (tRNA pseudouridine synthase D), IPR011760 (tRNA pseudouridine synthase D, core), IPR017091 (tRNA pseudouridine synthase D, eukaryotic)
31	ZK1307.8	ZK1307.8	n/a	chrII 9,625,448	contains similarity to Pfam domains PF07915 (Glucosidase II beta subunit-like protein) , PF00036 (EF hand) contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001907 (Peptidase S14, ClpP), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR009011 (Mannose-6-phosphate receptor, binding), IPR000886 (Endoplasmic reticulum, targeting sequence), IPR012913 (Glucosidase II beta subunit-like)
32	ZK856.5	ZK856.5	n/a	chrV 10,187,411	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domain IPR004843 (Metallophosphoesterase)
33	F59B8.2	F59B8.2	n/a	chrIV 9,439,991	contains similarity to Pfam domain PF00180 Isocitrate/isopropylmalate dehydrogenase contains similarity to Interpro domains IPR004790 (Isocitrate dehydrogenase NADP-dependent, eukaryotic), IPR001804 (Isocitrate/isopropylmalate dehydrogenase)
34	nmy-1	F52B10.1	n/a	chrX 2,913,788	nmy-1 encodes a class II non-muscle myosin heavy chain related to Drosophila zipper, which plays a role in several aspects of embryonic morphogenesis; in C. elegans, NMY-1 is required for embryonic elongation and establishment of normal body morphology; however, nmy-1 functions redundantly with another non-muscle myosin heavy chain gene, nmy-2, during elongation and establishment of normal body morphology; mutations in nmy-1 suppress the hypercontraction phenotype produced by mutations in mel-11, a myosin phosphatase that regulates actomyosin filament contraction; in addition, NMY-1 may partner with MLC-4, myosin light chain 4, during elongation; NMY-1 expression is detected during embryogenesis, particularly at the onset of elongation.
35	B0280.9	B0280.9	n/a	chrIII 7,121,829	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR001680 (WD40 repeat), IPR011046 (WD40 repeat-like), IPR015943 (WD40/YVTN repeat-like)
36	cyp-35A3	K09D9.2	0	chrV 4,023,531	C. elegans CYP-35A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
37	F54D5.4	F54D5.4	n/a	chrII 11,570,295	contains similarity to Haemonchus contortus NIM-2 protein.; TR:Q4QYX5
38	C18H2.2	C18H2.2	n/a	chrIII 7,679,866	contains similarity to Interpro domain IPR008962 (PapD-like)
39	nst-1	K01C8.9	n/a	chrII 8,281,963	nst-1 encodes a homolog of human GNL3 (OMIM:608011, nucleostemin) and GNL3L, and of S. cerevisiae NUG1; NST-1 may suppress tumorous growth in the germline; like PRO-1, -2, and -3, NST-1 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline; nucleostemin is a nucleolar protein found in stem cells that is required in quantitatively correct amounts (neither too little nor too much) for continued cell division and survival by stem cells or transformed cells; NST-1 is required in mass RNAi assays for normally rapid growth, larval viability, and normal body morphology and pigmentation.
40	Y43F4B.2	Y43F4B.2	n/a	chrIII 13,294,800	contains similarity to Interpro domain IPR009079 (Four-helical cytokine-like, core)
41	ZK795.3	ZK795.3	n/a	chrIV 12,559,996	contains similarity to Pfam domain PF04427 Brix domain contains similarity to Interpro domain IPR007109 (Brix)
42	ZK1236.1	ZK1236.1	n/a	chrIII 8,430,360	contains similarity to Pfam domains PF06421 (GTP-binding protein LepA C-terminus) , PF03144 (Elongation factor Tu domain 2) , PF00009 (Elongation factor Tu GTP binding domain) , PF00679 (Elongation factor G C-terminus) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR000795 (Protein synthesis factor, GTP-binding), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR004161 (Translation elongation factor EFTu/EF1A, domain 2), IPR006297 (GTP-binding protein LepA), IPR000640 (Translation elongation factor EFG/EF2, C-terminal), IPR013842 (GTP-binding protein LepA, C-terminal), IPR009022 (Elongation factor G, III and V)
43	drs-2	F10C2.6	n/a	chrV 12,050,440	drs-2 encodes a putative aspartyl-tRNA synthetase.
44	F32A5.3	F32A5.3	n/a	chrII 7,234,327	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
45	clec-57	F08H9.6	n/a	chrV 14,470,810	C. elegans CLEC-57 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
46	ncx-7	C07A9.11	n/a	chrIII 9,717,988	ncx-7 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6 and NCX-8/-10; NCX-7 may function intracellularly; NCX-7 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-7 has no obvious function in mass RNAi assays.
47	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
48	F31D4.8	F31D4.8	n/a	chrV 20,862,996	contains similarity to Streptococcus pneumoniae IS3-Spn1 putative transposase.; TR:Q9KK23
49	mog-5	EEED8.5	n/a	chrII 5,402,615	The mog-5 gene encodes a DEAH helicase orthologous to the Drosophila CG8241, the human HRH1, and the S. cerevisiae PRP22 proteins.
50	Y32B12B.2	Y32B12B.2	n/a	chrV 16,544,097	contains similarity to Vitis vinifera Putative uncharacterized protein.; TR:A5AD22