UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F02H6.2	F02H6.2	0	chrIV 14,197,604	contains similarity to Trichomonas vaginalis G3 Putative uncharacterized protein.; TR:A2F8N8
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	ZK287.7	ZK287.7	n/a	chrV 9,693,782	contains similarity to Homo sapiens Isoform 2 of RNA pseudouridylate synthase domain-containing protein 3; ENSEMBL:ENSP00000380410
4	R10E4.6	R10E4.6	n/a	chrIII 4,294,138
5	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
6	mec-14	F37C12.12	n/a	chrIII 7,191,528	mec-14 encodes a protein with similarity to the beta-subunits of Shaker-type potassium channels, which are members of the aldo-keto reductase superfamily; MEC-14 is required for response to gentle touch by the six touch receptor neurons, and likely functions to regulate activity of the MEC-4 and MEC-10 degenerin channels; mec-14 expression is detected solely in the touch receptor neurons and is dependent on the MEC-3 LIM domain transcription factor; proper MEC-14 localization in the touch receptor neurons is dependent on MEC-12/alpha-tubulin.
7	ekl-5	Y26E6A.1	n/a	chrX 13,915,941	C. elegans EKL-5 protein; contains similarity to Interpro domains IPR001579 (Glycoside hydrolase, chitinase active site), IPR006642 (Zinc finger, Rad18-type putative)
8	F28C6.2	F28C6.2	n/a	chrII 8,595,158	F28C6.2 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.1, which lies adjacent to F28C6.1 on chromosome II; loss of F28C6.2 activity via large-scale RNAi results in some embryonic lethality and low levels of larval arrest, body morphology defects, and uncoordinated locomotion.
9	bath-41	F37A4.9	n/a	chrIII 6,721,274	The F37A4.9 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
10	pcn-1	W03D2.4	n/a	chrIV 4,048,721	pcn-1 encodes the C. elegans ortholog of proliferating cell nuclear antigen (PCNA), an acidic protein that is an essential component of the DNA replication and repair machinery and serves as a processivity factor for DNA polymerase delta; PCN-1 is required for early embryogenesis and for proper germ-line development, and directly interacts with CKI-2, a cyclin-dependent kinase inhibitor homolog that may be required for cell cycle progression during embryogenesis, and with ATL-1/PI3K, KIN-20, MRT-2/RAD1, and RFC-1, proteins that all play a role in the DNA damage checkpoint pathway; PCN-1 is highly expressed in ovaries and developing embryos.
11	nhr-103	F44C8.4	n/a	chrV 2,226,236	nhr-103 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
12	Y57G11C.25	Y57G11C.25	n/a	chrIV 14,919,983	Y57G11C.25 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y57G11C.25 is predicted to function as an RNA-binding protein.
13	dro-1	F53A2.5	n/a	chrIII 13,342,882	C. elegans DRO-1 protein; contains similarity to Pfam domains PF00808 (Histone-like transcription factor (CBF/NF-Y) and archaeal histone) , PF00125 (Core histone H2A/H2B/H3/H4) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR007125 (Histone core), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
14	lsm-7	ZK593.7	n/a	chrIV 10,933,821	C. elegans LSM-7 protein; contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR010920 (Like-Sm ribonucleoprotein-related, core), IPR017132 (U6 snRNA-associated Sm-like protein LSm7)
15	C27A12.6	C27A12.6	n/a	chrI 6,054,583	contains similarity to Pfam domain PF01485 IBR domain contains similarity to Interpro domains IPR009060 (UBA-like), IPR002867 (Zinc finger, C6HC-type)
16	F39F10.3	F39F10.3	n/a	chrX 16,892,426	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
17	F23H12.7	F23H12.7	n/a	chrV 12,372,277	contains similarity to Interpro domain IPR001463 (Sodium:alanine symporter)
18	R06C7.2	R06C7.2	n/a	chrI 7,234,078	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86KG8
19	C32B5.10	C32B5.10	n/a	chrII 947,356
20	C34E10.8	C34E10.8	n/a	chrIII 5,251,598	contains similarity to Leishmania major strain Friedlin Proteophosphoglycan 5.; TR:Q4FX62
21	E02H9.7	E02H9.7	n/a	chrIII 2,445,442	contains similarity to Homo sapiens Uncharacterized protein MUC17 (Fragment); ENSEMBL:ENSP00000368750
22	F10D11.2	F10D11.2	n/a	chrI 8,437,292	contains similarity to Bacillus thuringiensis Pesticidial crystal protein cry8Ca (Insecticidal delta-endotoxinsCryVIIIC(a)) (Crystaline entomocidal protoxin) (130 kDa crystalsprotein).; SW:C8CA_BACTP
23	F14H3.3	F14H3.3	n/a	chrV 16,052,681	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000357794
24	pqn-11	C09G1.1	n/a	chrX 15,969,125	PQN-11 encodes an unfamiliar protein with a glutamine/asparagine-rich domain that is dispensable for viability and gross morphology.
25	F35H10.6	F35H10.6	n/a	chrIV 8,300,273	contains similarity to Pfam domain PF02996 Prefoldin subunit contains similarity to Interpro domains IPR004127 (Prefoldin alpha-like), IPR009053 (Prefoldin)
26	F02D10.6	F02D10.6	n/a	chrX 13,450,586	contains similarity to Cryptophlebia leucotreta granulosis virus Hypothetical protein.; TR:Q7T5R9
27	K08H2.3	K08H2.3	n/a	chrX 13,237,815	contains similarity to Rattus norvegicus Inositol 1,4,5-trisphosphate 3-kinase C.; TR:Q80ZG2
28	Y5F2A.4	Y5F2A.4	n/a	chrIV 11,077,311	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
29	C05E7.2	C05E7.2	n/a	chrX 12,939,625
30	ZC513.5	ZC513.5	n/a	chrV 8,037,288	contains similarity to Pfam domain PF03901 Alg9-like mannosyltransferase family contains similarity to Interpro domain IPR005599 (Alg9-like mannosyltransferase)
31	srh-52	R08H2.7	n/a	chrV 15,375,587	C. elegans SRH-52 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	C13A2.5	C13A2.5	n/a	chrV 7,277,113	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
33	mes-6	C09G4.5	n/a	chrIV 8,512,584	mes-6 encodes a WD repeat-containing protein that is orthologous to Drosophila Extra sex combs (Esc); as a member of a Polycomb-like chromatin repressive complex with MES-2 and MES-3, MES-6 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; MES-6 expression is detected in the nuclei of all cells during early embryogenesis, in the germline precursors Z2 and Z3 and faintly in some somatic cells during late embryogenesis and the L1 larval stage, widely in later larvae, and in germline and oocyte nuclei in adults; normal MES-6 distribution is dependent upon wild-type activity of MES-2 and MES-3, and likewise, distribution of MES-3 is dependent upon wild-type activity of MES-2 and MES-6
34	str-244	C50H11.9	n/a	chrV 3,058,396	C. elegans STR-244 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	age-1	B0334.8	n/a	chrII 11,523,196	age-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p110 catalytic subunit; AGE-1, supplied maternally and embryonically, is a central component of the C. elegans insulin-like signaling pathway, lying downstream of the DAF-2/insulin receptor and upstream of both the PDK-1 and AKT-1/AKT-2 kinases and the DAF-16 forkhead type transcription factor, whose negative regulation is the key output of the insulin signaling pathway; in accordance with its role in insulin signaling, AGE-1 activity is required for regulation of metabolism, life span, dauer formation, stress resistance, salt chemotaxis learning, fertility, and embryonic development; although the age-1 expression pattern has not yet been reported, ectopic expression studies indicate that pan-neuronal age-1 expression is sufficient to rescue life-span defects, while neuronal, intestinal, or muscle expression can partially rescue dauer formation, and neuronal or muscle expression can rescue metabolic defects.
36	rfc-3	C39E9.13	n/a	chrIV 13,096,350	C. elegans RFC-3 protein; contains similarity to Interpro domains IPR008921 (DNA polymerase III clamp loader subunit, C-terminal), IPR003593 (AAA+ ATPase, core)
37	fbxa-43	T20H9.2	n/a	chrIII 2,258,234	C. elegans FBXA-43 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
38	clec-223	C03E10.5	n/a	chrV 11,275,618	C. elegans CLEC-223 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR008160 (Collagen triple helix repeat)
39	srw-142	H05B21.3	n/a	chrV 2,957,658	C. elegans SRW-142 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
40	F54F7.6	F54F7.6	n/a	chrX 11,866,107	contains similarity to Homo sapiens Golgi autoantigen, golgin subfamily B member 1; ENSEMBL:ENSP00000315938
41	T24E12.2	T24E12.2	n/a	chrII 3,783,547
42	fsn-1	C26E6.5	n/a	chrIII 4,938,358	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins
43	spe-42	B0240.2	n/a	chrV 11,735,328	C. elegans SPE-42 protein; contains similarity to Pfam domain PF07782 DC-STAMP-like protein contains similarity to Interpro domain IPR012858 (DC-STAMP-like)
44	fut-3	F59E12.13	n/a	chrII 5,658,783	C. elegans FUT-3 protein; contains similarity to Pfam domain PF00852 Glycosyltransferase family 10 (fucosyltransferase) contains similarity to Interpro domain IPR001503 (Glycosyl transferase, family 10)
45	M01E11.3	M01E11.3	n/a	chrI 5,574,995	contains similarity to Pfam domain PF08585 Domain of unknown function (DUF1767) contains similarity to Interpro domain IPR013894 (Region of unknown function DUF1767)
46	srg-4	T12A2.12	n/a	chrIII 6,261,094	C. elegans SRG-4 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
47	C43F9.7	C43F9.7	n/a	chrIV 10,593,293	contains similarity to Xanthomonas campestris Hypothetical protein XCC1495.; TR:Q8PAI8
48	E03H4.4	E03H4.4	n/a	chrI 12,409,488	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
49	srh-123	F08E10.3	n/a	chrV 17,474,702	C. elegans SRH-123 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	C44C10.4	C44C10.4	n/a	chrX 11,694,526	contains similarity to Pfam domain PF02463 RecF/RecN/SMC N terminal domain contains similarity to Interpro domain IPR003395 (RecF/RecN/SMC protein, N-terminal)