UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cut-3	F22B5.3	0	chrII 8,445,930	C. elegans CUT-3 protein; contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	ZK675.4	ZK675.4	n/a	chrII 7,911,649	contains similarity to Homo sapiens Nuclear pore glycoprotein p62; ENSEMBL:ENSP00000305503
4	ces-2	ZK909.4	n/a	chrI 14,963,425	ces-2 encodes a basic region leucine-zipper (bZIP) transcription factor, most similar in sequence and binding specificity to the PAR (proline- and acid-rich) subfamily of bZIP proteins; ces-2 is required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons, and is transcriptionally inhibited by activated LET-60(G12V).
5	K08B4.2	K08B4.2	n/a	chrIV 6,075,712
6	C33D9.5	C33D9.5	n/a	chrIV 8,779,611	C33D9.5 encodes a predicted coiled-coil protein; as loss of C33D9.5 activity via large-scale RNAi results in no obvious abnormalities, the precise role of C33D9.5 in C. elegans development and/or behavior is not yet known.
7	ppt-1	F44C4.5	n/a	chrV 6,625,504	ppt-1 encodes the C. elegans palmitoyl protein thioesterase-1 ortholog; by homology PPT-1 is predicted to function in degradation of palmitoylated proteins and ppt-1 mutations result in loss of enzymatic activity from mixed-stage extracts; in C. elegans, ppt-1 activity is essential for mitochondrial organization and biogenesis in neuronal and muscle cells, as well as for proper timing of the onset of both the L4-to-adult molt and egg laying; ppt-1 is also required for normal egg-laying behavior and for a fully normal adult
8	skr-21	K08H2.1	n/a	chrX 13,226,159	The skr-21 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-21(RNAi) animals are at least superficially normal.
9	F42A10.6	F42A10.6	n/a	chrIII 6,176,450
10	ins-2	ZK75.2	n/a	chrII 5,988,821	ins-2 encodes an insulin-like peptide.
11	F58E6.3	F58E6.3	n/a	chrV 9,748,618	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07699 (GCC2 and GCC3) (4)contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site)
12	F46E10.2	F46E10.2	n/a	chrV 6,520,674	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001030 (Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)
13	ceh-43	C28A5.4	n/a	chrIII 4,448,260	A homeobox protein of the Distal-less (Dll) class that is required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability; it is predominantly expressed in the head hypdodermis, neuronal support cells and CAN neurons.
14	C41H7.2	C41H7.2	n/a	chrII 3,015,393	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
15	bath-10	Y49F6C.4	n/a	chrII 3,375,923	C. elegans BATH-10 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
16	fbxb-8	F49B2.1	n/a	chrI 14,302,931	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
17	W10D9.1	W10D9.1	n/a	chrII 454,887
18	fbxb-16	ZC204.10	n/a	chrII 1,651,202	fbxb-16 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-16 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
19	col-74	ZK1248.2	n/a	chrII 5,831,409	C. elegans COL-74 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domain IPR008160 (Collagen triple helix repeat)
20	C31H5.4	C31H5.4	n/a	chrI 9,042,426	contains similarity to Oryza sativa P0681F05.20 protein.; TR:Q8GVP7
21	R07C3.11	R07C3.11	n/a	chrII 908,164
22	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
23	ZK418.3	ZK418.3	n/a	chrIII 7,070,514	contains similarity to Homo sapiens Transmembrane protein 17; ENSEMBL:ENSP00000335094
24	ttr-20	F36A4.8	n/a	chrIV 4,246,321	C. elegans TTR-20 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
25	fbxb-10	T08E11.6	n/a	chrII 1,817,843	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
26	F46B3.7	F46B3.7	n/a	chrV 20,613,776	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
27	F13H10.1	F13H10.1	n/a	chrIV 11,004,784	contains similarity to Oryza sativa Putative pM5 collagenase.; TR:Q93W04
28	ZC443.2	ZC443.2	n/a	chrV 12,810,803	contains similarity to Listeria innocua Hypothetical protein lin2372.; TR:Q929A5
29	F15B10.3	F15B10.3	n/a	chrIV 6,603,277	contains similarity to Interpro domain IPR016072 (SKP1 component, dimerisation)
30	Y106G6D.1	Y106G6D.1	n/a	chrI 10,108,184	contains similarity to Methanocaldococcus jannaschii DNA double-strand break repair rad50 ATPase.; SW:Q58718
31	T04B8.3	T04B8.3	n/a	chrII 628,093	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
32	tyr-3	F21C3.2	n/a	chrI 7,276,425	C. elegans TYR-3 protein; contains similarity to Pfam domains PF00264 (Common central domain of tyrosinase) , PF01549 (ShK domain-like) (4)contains similarity to Interpro domains IPR008922 (Di-copper centre-containing), IPR002227 (Tyrosinase), IPR003582 (Metridin-like ShK toxin)
33	cut-6	M142.2	9e-57	chrIII 10,913,915	C. elegans CUT-6 protein; contains similarity to Pfam domains PF00100 (Zona pellucida-like domain) , PF00092 (von Willebrand factor type A domain) contains similarity to Interpro domains IPR001507 (Endoglin/CD105 antigen), IPR002035 (von Willebrand factor, type A)
34	C17H1.2	C17H1.2	n/a	chrI 13,102,913	contains similarity to Apple stem grooving virus Genome polyprotein [Contains: RNA replicase (EC 2.7.7.48); Helicase;sCoat protein].; SW:POLR_ASGVP
35	B0554.1	B0554.1	n/a	chrV 438,570
36	C14A6.2	C14A6.2	n/a	chrV 18,151,568	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
37	C33E10.1	C33E10.1	n/a	chrX 17,305,742	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
38	C47F8.7	C47F8.7	n/a	chrI 12,326,720
39	fbxb-82	T17A3.4	n/a	chrIII 142,689	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
40	F23A7.1	F23A7.1	n/a	chrX 16,217,447	contains similarity to Saccharomyces cerevisiae RSC4 is a member of RSC complex, which remodels the structure of chromatin.; SGD:YKR008W
41	fbxb-66	Y40B1B.3	n/a	chrI 13,424,575	C. elegans FBXB-66 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
42	btb-10	K02E7.9	n/a	chrII 1,060,263	C. elegans BTB-10 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
43	F48C1.8	F48C1.8	n/a	chrI 5,335,938	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein)
44	T27E4.1	T27E4.1	n/a	chrV 9,093,497	contains similarity to Interpro domain IPR008973 (C2 calcium/lipid-binding region, CaLB)
45	D1086.5	D1086.5	n/a	chrV 14,089,587	contains similarity to Bison bonasus MHC class II DR-beta chain (Fragment).; TR:O19256
46	T23B3.2	T23B3.2	n/a	chrI 6,716,467	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
47	fbxb-22	Y56A3A.10	n/a	chrIII 11,882,947	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	T24C4.2	T24C4.2	n/a	chrIII 868,674
49	Y7A9D.1	Y7A9D.1	n/a	chrIV 16,381,762	contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
50	F08H9.3	F08H9.3	n/a	chrV 14,462,384	F08H9.3 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the larval pharynx and the anterior adult pharynx), and its expression is not strongly induced by heat shock; however, F08H9.3 expression is increased by heat shock (with adult expression in the full pharynx) and probably aids heat shock resistance, since F08H9.3(RNAi) animals have sensitivity to heat shock that is sporadically higher than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.