UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F28H6.2	F28H6.2	7.999999999999999e-134	chrX 14,142,630	contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
2	Y37H9A.3	Y37H9A.3	n/a	chrI 13,785,519	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR006608 (Protein of unknown function DM14), IPR000008 (C2 calcium-dependent membrane targeting)
3	Y7A5A.6	Y7A5A.6	n/a	chrX 15,798,435	contains similarity to Schizosaccharomyces pombe Putative transcriptional regulatory protein, phd finger.; TR:Q9HDV4
4	glb-11	C36E8.2	n/a	chrIII 3,990,752	glb-11 encodes a globin; glb-11 transcription is higher in L3 and dauers than in young adults; glb-11 has no obvious function in mass RNAi assays; glb-11 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background.
5	php-3	Y75B8A.1	n/a	chrIII 12,075,804	C. elegans PHP-3 protein; contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
6	nep-2	T05A8.4	n/a	chrII 2,721,578	T05A8.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T05A8.4 is an ortholog of mammalian neutral endopeptidase (NEP), expressed on the brush-border membranes of kidney; more generally, T05A8.4 falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
7	R02F11.2	R02F11.2	n/a	chrV 4,795,145
8	T11F1.3	T11F1.3	n/a	chrII 2,955,703
9	pqn-84	Y41C4A.5	n/a	chrIII 11,701,451	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
10	adm-2	C04A11.4	n/a	chrX 13,691,794	adm-2 encodes a protein containing a snake venom disintegrin-domain and a metalloprotease-like domain (i.e., a protein of the ADAM family); like ADM-1, ADM-2 is homologous to a mammalian sperm glycoprotein (PH-30/fertilin) implicated in sperm-egg fusion, and ADM-2 might thus be a fusogenic protein mediating the merging of plasma membranes during development.
11	F02E11.3	F02E11.3	n/a	chrII 3,273,416	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
12	Y81G3A.4	Y81G3A.4	n/a	chrII 13,092,774	contains similarity to Guillardia theta 60S acidic ribosomal protein P0.; TR:Q98S65
13	srxa-15	Y44A6B.2	n/a	chrV 20,638,710	C. elegans SRXA-15 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
14	T02H6.8	T02H6.8	n/a	chrII 681,180
15	fax-1	F56E3.4	n/a	chrX 3,198,294	fax-1 encodes a conserved nuclear receptor that contains two C4-type zinc fingers and is orthologous to the vertebrate photoreceptor-specific nuclear receptor PNR (OMIM:604485, mutated in enhanced S-cone syndrome and retinitis pigmentosa); fax-1 is required for normal locomotion and neuron fate specification, including specification of the AVA, AVE, and AVK interneurons and proper axon pathfinding of the AVK, HSNL, and PVQL axons; expression of reporter gene fusions in fax-1 mutants suggests that fax-1 functions by regulating expression of a number of downstream targets, including nmr-1 and nmr-2, opt-3, flp-1, and ncs-1; in some neurons, fax-1 regulates expression combinatorially with unc-42, which encodes a paired-like homeodomain protein that additionally, regulates fax-1 expression in AVK neurons; FAX-1 is expressed in the nuclei of 18 neurons, including the AVK, AVA, AVB, and AVE interneurons, beginning at mid-embryogenesis and continuing through larval and adult stages; FAX-1 is also seen in two non-neuronal cell types: the distal tip cells (DTCs), from L2 to L4 larval stages, and two pairs of vulval cells in L4 animals.
16	pbo-6	F11C7.1	n/a	chrX 17,431,052	pbo-6/lgc-3 encodes a proton-gated ion channel which has no known function, but that is thought to form functional heterodimers with PBO-5/LGC-2; PBO-6 has no obvious non-nematode orthologs, but is paralogous to PBO-5; while heterologous PBO-6 has no activity when expressed in Xenopus oocytes, it produces strong currents when coexpressed with PBO-5 and stimulated by pH 6.0; PBO-6 is expressed in the most posterior bodywall muscles; unlike pbo-5 mutants, pbo-6(ok1564) mutants and pbo-6(RNAi) animals have no obvious phenotypes.
17	srd-70	F48F5.4	n/a	chrV 20,450,660	C. elegans SRD-70 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	C33E10.5	C33E10.5	n/a	chrX 17,276,148	contains similarity to Interpro domain IPR000173 (Glyceraldehyde 3-phosphate dehydrogenase)
19	gcy-37	C54E4.3	n/a	chrIV 2,154,905	gcy-37 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-37 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-37 in C. elegans development and/or behavior is not yet known; GCY-37 expression in neurons connected to the pseudocoelom suggests, however, that GCY-37 may play a role in fluid homeostasis.
20	srw-7	R08F11.5	n/a	chrV 3,806,992	C. elegans SRW-7 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
21	T28C12.1	T28C12.1	n/a	chrV 6,332,957	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
22	abf-4	Y38H6C.22	n/a	chrV 20,553,545	abf-4 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-4 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.
23	srt-8	C50H11.2	n/a	chrV 3,087,272	C. elegans SRT-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
24	F28B4.1	F28B4.1	n/a	chrX 3,205,615
25	H36L18.1	H36L18.1	n/a	chrX 12,650,135	contains similarity to Pfam domains PF00413 (Matrixin) , PF00045 (Hemopexin) (3)contains similarity to Interpro domains IPR000585 (Hemopexin), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR006026 (Peptidase, metallopeptidases), IPR001818 (Peptidase M10A and M12B, matrixin and adamalysin)
26	C46E10.5	C46E10.5	n/a	chrII 3,712,130
27	R10F2.4	R10F2.4	n/a	chrIII 2,921,110	contains similarity to Interpro domain IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal)
28	srb-5	C27D6.6	n/a	chrII 5,162,671	C. elegans SRB-5 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
29	clec-229	H02K04.1	n/a	chrV 15,340,763	C. elegans CLEC-229 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR001202 (WW/Rsp5/WWP)
30	srh-298	Y94A7B.5	n/a	chrV 17,819,902	C. elegans SRH-298 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
31	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
32	E01G4.1	E01G4.1	n/a	chrII 13,445,298	contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
33	W04C9.5	W04C9.5	n/a	chrI 464,897	contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
34	R09A1.2	R09A1.2	n/a	chrV 1,020,657	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
35	R03G5.6	R03G5.6	n/a	chrX 7,808,111
36	K12H6.12	K12H6.12	n/a	chrII 2,810,497	contains similarity to Interpro domain IPR015880 (Zinc finger, C2H2-like)
37	srd-49	R04B5.8	n/a	chrV 10,095,486	C. elegans SRD-49 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
38	F21D9.4	F21D9.4	n/a	chrV 19,255,280	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
39	F49B2.6	F49B2.6	n/a	chrI 14,335,445	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
40	T13A10.1	T13A10.1	n/a	chrIV 6,276,666	contains similarity to Danio rerio Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-).; SW:Q8JFV8
41	spe-38	Y52B11A.1	n/a	chrI 10,965,401	C. elegans SPE-38 protein ;
42	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
43	Y39E4B.13	Y39E4B.13	n/a	chrIII 13,092,265	contains similarity to Caulobacter crescentus Localization factor podJL (Polar organelle development protein)s[Contains: Localization factor podJS].; SW:PODJ_CAUCR
44	C18D11.1	C18D11.1	n/a	chrIII 11,818,072	contains similarity to Sporobolus stapfianus Hypothetical protein.; TR:O04820
45	R13A1.7	R13A1.7	n/a	chrIV 7,213,362
46	D1081.4	D1081.4	n/a	chrI 8,475,188	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
47	F49C12.1	F49C12.1	n/a	chrIV 9,295,603	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
48	F13D2.4	F13D2.4	n/a	chrX 11,188,488	contains similarity to Homo sapiens Isoform 3 of CD109 antigen precursor; HI:HIT000020743
49	F16H6.6	F16H6.6	n/a	chrV 18,205,786	contains similarity to Anthyllis vulneraria subsp lapponica Maturase-like protein.; TR:Q8HUG8
50	bbs-9	C48B6.8	n/a	chrI 6,920,270	C. elegans BBS-9 protein ; contains similarity to Homo sapiens 95 kDa protein; ENSEMBL:ENSP00000346214