UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F30F8.1	F30F8.1	0	chrI 7,834,052	contains similarity to Mus musculus Nuclear factor of activated T cells 5 (T cell transcription factorsNFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).; SW:NFT5_MOUSE
2	F02H6.1	F02H6.1	n/a	chrIV 14,200,489	contains similarity to Human herpesvirus 8 ORF73.; TR:Q91LX9
3	F18E2.1	F18E2.1	n/a	chrV 12,758,672	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR015914 (Purple acid phosphatase, N-terminal), IPR004843 (Metallophosphoesterase)
4	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
5	F27C1.6	F27C1.6	n/a	chrI 5,424,977	contains similarity to Pfam domain PF04615 Utp14 protein contains similarity to Interpro domain IPR006709 (Small-subunit processome, Utp14)
6	C47F8.6	C47F8.6	n/a	chrI 12,320,092	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
7	T19D12.7	T19D12.7	n/a	chrII 6,648,354	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
8	mdf-1	C50F4.11	n/a	chrV 9,542,977	mdf-1 encodes a coiled-coil domain-containing protein that is orthologous to the Saccharomyces cerevisiae mitotic spindle checkpoint protein Mad1p; consistent with a role as a checkpoint protein, MDF-1 is required in C. elegans for mitotic genome stability and hence, long-term survival and fertility; in vitro, MDF-1 interacts with MDF-2, the C. elegans Mad2p ortholog.
9	T09E11.9	T09E11.9	n/a	chrI 12,348,814	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
10	srw-69	F18E3.5	n/a	chrV 7,428,134	C. elegans SRW-69 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
11	C14B9.8	C14B9.8	n/a	chrIII 8,142,045	C14B9.8 is orthologous to the human gene PHOSPHORYLASE KINASE, LIVER, ALPHA-2 SUBUNIT (PHKA2; OMIM:306000), which when mutated leads to liver glycogenosis.
12	C29E6.4	C29E6.4	n/a	chrIV 11,881,077	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR001507 (Endoglin/CD105 antigen)
13	cyp-14A3	K09A11.4	n/a	chrX 13,272,959	C. elegans CYP-14A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
14	him-14	ZK1127.11	n/a	chrII 7,067,448	him-14 encodes a germline-specific member of the MutS family of DNA mismatch repair (MMR) proteins that is orthologous to human MSH4 and Saccharomyces cerevisiae Msh4p; during the pachytene stage of meiosis, HIM-14 activity is required for promoting crossing over between homologous chromosomes and thus, for chiasmata formation and proper chromosome segregation; in contrast, HIM-14 activity does not appear to be required for mismatch repair, nor for chromosome pairing or synapsis; him-14 mRNA expression is detected exclusively in the germline.
15	nhr-163	C33G8.12	n/a	chrV 6,984,709	C. elegans NHR-163 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
16	bath-13	F40B1.1	n/a	chrII 2,521,505	C. elegans BATH-13 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
17	ZK721.3	ZK721.3	n/a	chrX 8,785,606
18	fbxa-157	C06H5.2	n/a	chrV 17,900,819	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
19	ZC404.10	ZC404.10	n/a	chrV 6,801,320	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
20	xnp-1	B0041.7	n/a	chrI 4,668,742	xnp-1 encodes an ATP-dependent DNA helicase of the SNF2 family that is orthologous to human XNP/ATR-X, which is associated with a number of X-linked mental retardation syndromes; in C. elegans, xnp-1 activity is required at high temperatures for embryogenesis, somatic gonad development, fertility, and vulval morphogenesis; in addition, animals doubly mutant for xnp-1 and lin-35/Rb, hpl-2/HP1, or nucleosome remodelling and histone deacetylase (NuRD) complex members such as lin-53 and let-418, display larval arrest with growth cessation but continued cell proliferation; xnp-1 is also required, with lin-35/Rb and hpl-2/HP1, for proper regulation of transgene expression; xnp-1 mRNA, detectable in embryos and the germline by in situ hybridization, is expressed at highest levels in embryos with decreasing levels seen in successive larval stages; xnp-1 transcriptional reporter fusions exhibit strong expression beginning at mid-embryogenesis but fading by embryonic morphogenesis; at hatching, expression is observed in all dividing cells including the P lineage, and at later larval stages expression is observed in the vulval precursor cells.
21	T11G6.5	T11G6.5	n/a	chrIV 10,839,263	contains similarity to Interpro domain IPR000694 (Proline-rich region)
22	elks-1	F42A6.9	n/a	chrIV 3,346,268	elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina.
23	D2089.3	D2089.3	n/a	chrII 10,663,519	contains similarity to Homo sapiens hypothetical protein LOC150383; ENSEMBL:ENSP00000325301
24	cids-1	C02F5.4	n/a	chrIII 8,245,008	C. elegans CIDS-1 protein; contains similarity to Pfam domain PF04818 Protein of unknown function, DUF618 contains similarity to Interpro domains IPR006569 (Regulation of nuclear pre-mRNA protein), IPR006903 (Protein of unknown function DUF618), IPR008942 (ENTH/VHS)
25	C40H1.3	C40H1.3	n/a	chrIII 9,328,239	contains similarity to Homo sapiens Protein; VG:OTTHUMP00000003630
26	C35C5.6	C35C5.6	n/a	chrX 11,566,764	contains similarity to Drosophila melanogaster Flybase gene name is CG2478-PA;; FLYBASE:CG2478
27	F41H8.1	F41H8.1	n/a	chrV 834,574	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
28	K07C11.10	K07C11.10	n/a	chrV 8,226,436	contains similarity to Homo sapiens hypothetical protein isoform 1; ENSEMBL:ENSP00000381337
29	cpb-3	B0414.5	n/a	chrI 5,790,196	cpb-3 encodes a CPEB orthologous to Drosophila ORB, zebrafish ZORBA, and human CPEB1, and paralogous to FOG-1 and CPB-1/2; CPB-3 inhibits physiological apoptosis in oocytes, keeping it down to a normal level of ~50% in hermaphrodite gonads; independently of apoptosis, CPB-3 is also required for normal oogenesis, sperm/oocyte switching (upstream of FEM-3), and the transistion from mitosis to meiosis by oocytes (in parallel with GLD-3); cpb-3(RNAi) results in elevated (though not 100%) physiological germ cell apoptosis, independent of CEP-1; in cpb-3(RNAi) animals, excess physiological apoptosis actually promotes fertility, since cpb-3(RNAi) hermaphrodites have larger brood sizes than those with apoptosis suppressed by ced-3(n717), and aging ced-3(n717);cpb-3(RNAi) animals have abnormal oocytes that fail to exit pachytene and proceed through diakinesis; CPB-3 is mainly cytoplasmic, and strongly expressed in pachytene oocytes; cpb-3(bt17);daz-1(tj3) hermaphrodites have a synthetic phenotype of total sterility and masculinization; CPB-3 colocalizes with DAZ-1 in vivo, coimmunoprecipitates with DAZ-1, and binds DAZ-1 in two-hybrid assays.
30	F48G7.4	F48G7.4	n/a	chrV 620,860
31	srg-2	C18F10.5	n/a	chrIII 6,259,346	srg-2 encodes a predicted seven transmembrane domain G protein-coupled chemosensory receptor; an SRG-2::GFP fusion protein is expressed exclusively in the cilia of ASK sensory neurons, which are believed to be involved in chemotaxis to lysine and sensory regulation of egg laying; localization of SRG-2 to ASK cilia does not appear to depend upon wild-type activity of either odr-4 or odr-8.
32	srw-119	K12D9.7	n/a	chrV 2,999,188	C. elegans SRW-119 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
33	cyp-34A1	T10H4.10	n/a	chrV 15,286,741	C. elegans CYP-34A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
34	F28F8.7	F28F8.7	n/a	chrV 15,579,943	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domain IPR000949 (ELM2)
35	unc-8	R13A1.4	n/a	chrIV 7,200,978	unc-8 encodes an amiloride-sensitive DEG/ENaC cation-selective channel subunit orthologous to human ENaCB (OMIM:600760, associated with Liddle syndrome, an autosomal dominant form of hypertension); UNC-8 is predicted to function as part of a mechanically gated channel that responds to stretch, and is required for modulating the sinusoidal body wave that is characteristic of C. elegans locomotion; unc-8 interacts genetically with unc-1 and unc-24, which encode stomatin-like proteins, and with mec-6, which encodes a paraoxonase; UNC-8 is expressed in motor neurons, sensory neurons, and interneurons in the nerve ring; UNC-8 may form a channel with the degenerin DEL-1, with which it is coexpressed in ventral cord motor neurons.
36	Y75B8A.7	Y75B8A.7	n/a	chrIII 12,156,145	contains similarity to Pfam domain PF04006 Mpp10 protein contains similarity to Interpro domains IPR012173 (U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p), IPR007151 (Mpp10 protein)
37	ZC376.6	ZC376.6	n/a	chrV 14,188,934	contains similarity to Interpro domain IPR001028 (Glycoprotein phospholipase D)
38	K10C9.4	K10C9.4	n/a	chrV 1,051,572	contains similarity to Interpro domain IPR003945 (NADH-plastoquinone oxidoreductase, chain 5)
39	Y57G7A.6	Y57G7A.6	n/a	chrII 1,283,801	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
40	D1065.1	D1065.1	n/a	chrV 4,075,636	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
41	C34D4.1	C34D4.1	n/a	chrIV 7,158,487	contains similarity to Interpro domain IPR000956 (Stathmin)
42	K12H4.2	K12H4.2	n/a	chrIII 8,047,973	contains similarity to Pfam domain PF02410 Domain of unknown function DUF143 contains similarity to Interpro domain IPR004394 (Iojap-related protein)
43	T18D3.6	T18D3.6	n/a	chrX 12,450,290	contains similarity to Streptomyces coelicolor Chromosomal replication initiator protein dnaA.; SW:DNAA_STRCO
44	str-19	T23D5.7	n/a	chrV 15,743,832	C. elegans STR-19 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	nhr-256	ZK697.2	n/a	chrV 1,745,848	C. elegans NHR-256 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
46	gck-4	C04A11.3	n/a	chrX 13,679,590	C. elegans GCK-4 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
47	C01B10.9	C01B10.9	n/a	chrIV 6,633,581	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR017850 (Alkaline-phosphatase-like, core domain)
48	F40G12.4	F40G12.4	n/a	chrV 14,268,178	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
49	srh-247	C31B8.13	n/a	chrV 2,933,658	C. elegans SRH-247 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)