UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	rps-8	F42C5.8	2e-117	chrIV 7,313,435	rps-8 encodes a small ribosomal subunit S8 protein; by homology, RPS-8 is predicted to function in protein biosynthesis; in C. elegans, RPS-8 activity is required for germline development and the overall health of the animal.
2	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
3	R03H4.1	R03H4.1	n/a	chrV 9,018,100	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
4	ram-5	T24C2.1	n/a	chrX 14,553,138	ram-5 encodes a novel transmembrane protein; during male tail development, ram-5 activity is required in ray structural cells for proper sensory ray morphogenesis; a RAM-5::GFP fusion protein is expressed in all of the ray structural cells of the male tail, as well as additional sensory support cells in both hermaphrodites and males, including those of the inner labial sensilla as well as the ADE, PDE, and phasmid socket cells.
5	gcy-37	C54E4.3	n/a	chrIV 2,154,905	gcy-37 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-37 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-37 in C. elegans development and/or behavior is not yet known; GCY-37 expression in neurons connected to the pseudocoelom suggests, however, that GCY-37 may play a role in fluid homeostasis.
6	srh-298	Y94A7B.5	n/a	chrV 17,819,902	C. elegans SRH-298 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	F16H6.5	F16H6.5	n/a	chrV 18,202,582	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
8	R07B1.8	R07B1.8	n/a	chrX 9,871,676
9	C34E11.2	C34E11.2	n/a	chrX 11,808,336	contains similarity to Pfam domain PF03166 MH2 domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000694 (Proline-rich region), IPR001132 (SMAD domain, Dwarfin-type), IPR017855 (SMAD domain-like)
10	qui-1	Y45F10B.10	n/a	chrIV 13,568,114	The qui-1 gene encodes a protein of unknown function that contains several WD-40 domains.
11	snt-2	F42G9.7	n/a	chrIII 789,889	C. elegans SNT-2 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
12	K01A11.2	K01A11.2	n/a	chrIII 3,426,861	contains similarity to Xenopus laevis LOC495955 protein.; TR:Q5PQ79
13	K09E3.5	K09E3.5	n/a	chrX 17,109,938	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
14	F09C11.1	F09C11.1	n/a	chrIV 543,658
15	K09H11.5	K09H11.5	n/a	chrV 5,728,063
16	fbxa-130	F42A6.8	n/a	chrIV 3,340,450	C. elegans FBXA-130 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
17	F23H11.6	F23H11.6	n/a	chrIII 914,468
18	T25G3.4	T25G3.4	n/a	chrI 7,566,145	T25G3.4 encodes a putative mitochondrial glycerol-3-phosphate dehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2 (OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcripts are not obviously enriched during oogenesis, but T25G3.4 is predicted to be coexpressed in an operon with chs-1 and T25G3.3; such coexpression, if real, may simply reflect all three genes being required for oogenesis, rather than some more detailed functional connection; T25G3.4 has no obvious function in mass RNAi assays.
19	F18A11.3	F18A11.3	n/a	chrII 13,036,522	contains similarity to Candida albicans Multidrug resistance protein CDR2.; SW:CDR2_CANAL
20	Y37H9A.3	Y37H9A.3	n/a	chrI 13,785,519	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR006608 (Protein of unknown function DM14), IPR000008 (C2 calcium-dependent membrane targeting)
21	srx-118	T21B4.12	n/a	chrII 12,526,763	C. elegans SRX-118 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
22	F56C9.8	F56C9.8	n/a	chrIII 7,317,655
23	F53H2.3	F53H2.3	n/a	chrV 20,399,182	contains similarity to Interpro domain IPR006034 (Asparaginase/glutaminase)
24	C33A11.2	C33A11.2	n/a	chrX 15,367,917	contains similarity to Drosophila melanogaster Flybase gene name is CG4025-PA;; FLYBASE:CG4025
25	ZK563.2	ZK563.2	n/a	chrX 3,371,077	contains similarity to Pfam domain PF02690 Na+/Pi-cotransporter contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR003841 (Na+/Pi-cotransporter)
26	T27A8.5	T27A8.5	n/a	chrX 16,065,286	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
27	srh-112	T19C9.2	n/a	chrV 17,225,620	C. elegans SRH-112 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	str-149	Y32B12B.5	n/a	chrV 16,574,182	C. elegans STR-149 protein ;
29	F08D12.12	F08D12.12	n/a	chrII 2,784,540	contains similarity to Homo sapiens hypothetical protein; VG:OTTHUMP00000024537
30	R05D7.5	R05D7.5	n/a	chrI 12,186,205	contains similarity to Ascaris suum P40.; TR:Q7YXJ9
31	clec-92	Y52B11A.5	n/a	chrI 11,016,484	C. elegans CLEC-92 protein; contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
32	F28B1.5	F28B1.5	n/a	chrV 17,058,496
33	srx-104	F40H7.7	n/a	chrII 3,699,139	C. elegans SRX-104 protein ;
34	col-162	Y2H9A.3	n/a	chrV 13,442,665	C. elegans COL-162 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
35	C18D11.1	C18D11.1	n/a	chrIII 11,818,072	contains similarity to Sporobolus stapfianus Hypothetical protein.; TR:O04820
36	mec-10	F16F9.5	n/a	chrX 8,467,984	The mec-10 gene encodes an amiloride-sensitive Na+ channel protein (degenerin) required to sense gentle mechanical stimuli (e.g. touch) along the body wall; it is paralogous to mec-4, which has similar function in vivo.
37	osm-7	T05D4.4	n/a	chrIII 13,578,274	C. elegans OSM-7 protein ;
38	sph-1	F42G8.11	n/a	chrIV 8,132,914	sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain.
39	dmd-3	Y43F8C.10	n/a	chrV 19,652,807	C. elegans DMD-3 protein; contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
40	Y37D8A.22	Y37D8A.22	n/a	chrIII 12,937,773	contains similarity to Danio rerio Transmembrane protein 49.; SW:Q6NYY9
41	cof-2	C48E7.5	n/a	chrI 6,251,698	cof-2 encodes a homolog of human GLC1A, which when mutated leads to glaucome primary open angle (OMIM:137750)
42	nhr-181	F38H12.3	n/a	chrV 4,097,665	nhr-181 encodes a putative nuclear hormone receptor (NHR), belonging to a large nematode-specific expanded family of NHRs, that inhibits CEP-1- and HUS-1-dependent germline apoptosis as do BMK-1, RAD-50, and RAD-51.
43	R07B1.6	R07B1.6	n/a	chrX 9,867,228	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
44	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)
45	math-5	C16C4.10	n/a	chrII 1,882,210	C. elegans MATH-5 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
46	C07G1.7	C07G1.7	n/a	chrIV 8,211,372
47	R06B10.2	R06B10.2	n/a	chrIII 975,911	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
48	T13C2.2	T13C2.2	n/a	chrII 6,795,686
49	T24A6.16	T24A6.16	n/a	chrV 3,562,186	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
50	fax-1	F56E3.4	n/a	chrX 3,198,294	fax-1 encodes a conserved nuclear receptor that contains two C4-type zinc fingers and is orthologous to the vertebrate photoreceptor-specific nuclear receptor PNR (OMIM:604485, mutated in enhanced S-cone syndrome and retinitis pigmentosa); fax-1 is required for normal locomotion and neuron fate specification, including specification of the AVA, AVE, and AVK interneurons and proper axon pathfinding of the AVK, HSNL, and PVQL axons; expression of reporter gene fusions in fax-1 mutants suggests that fax-1 functions by regulating expression of a number of downstream targets, including nmr-1 and nmr-2, opt-3, flp-1, and ncs-1; in some neurons, fax-1 regulates expression combinatorially with unc-42, which encodes a paired-like homeodomain protein that additionally, regulates fax-1 expression in AVK neurons; FAX-1 is expressed in the nuclei of 18 neurons, including the AVK, AVA, AVB, and AVE interneurons, beginning at mid-embryogenesis and continuing through larval and adult stages; FAX-1 is also seen in two non-neuronal cell types: the distal tip cells (DTCs), from L2 to L4 larval stages, and two pairs of vulval cells in L4 animals.