UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F53F8.4	F53F8.4	5e-121	chrV 20,686,618	contains similarity to Pfam domain PF01682 DB module contains similarity to Interpro domain IPR002602 (Protein of unknown function DB)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	Y73F4A.2	Y73F4A.2	n/a	chrIV 9,042,830	contains similarity to Pfam domain PF03351 DOMON domain contains similarity to Interpro domains IPR005018 (DOMON related), IPR008960 (Carbohydrate-binding family 9/cellobiose dehydrogenase, cytochrome), IPR013050 (DOMON)
4	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
5	F07C3.9	F07C3.9	n/a	chrV 9,254,456
6	B0228.1	B0228.1	n/a	chrII 7,756,388
7	F53A9.2	F53A9.2	n/a	chrX 8,709,863	contains similarity to Interpro domains IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR002395 (HMW kininogen)
8	F20B6.6	F20B6.6	n/a	chrX 4,201,908	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
9	ZK593.2	ZK593.2	n/a	chrIV 10,913,905	contains similarity to Paramecium bursaria chlorella virus 1 A105L protein.; TR:Q84426
10	B0564.3	B0564.3	n/a	chrIV 13,108,976	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
11	ttr-10	F19F10.4	n/a	chrV 7,553,390	C. elegans TTR-10 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
12	dlc-2	M18.2	n/a	chrIV 12,111,060	dlc-2 encodes a putative dynein light chain 1; DLC-2 is orthologous to human DYNLL1 (OMIM:601562) and DYNLL2 (OMIM:608942), but much more divergent from them than its paralog DLC-1; its other paralogs are DLC-3/-5 and DLC-6.
13	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
14	R07C12.3	R07C12.3	n/a	chrIV 4,145,897
15	F41G3.10	F41G3.10	n/a	chrII 6,749,016	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
16	ttr-21	F09F3.6	n/a	chrV 13,854,097	C. elegans TTR-21 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
17	C33H5.13	C33H5.13	n/a	chrIV 7,791,950	contains similarity to Xenopus tropicalis UPF0467 protein C5orf32 homolog.; SW:Q28H62
18	F14D2.7	F14D2.7	n/a	chrII 3,337,168	contains similarity to Interpro domain IPR006642 (Zinc finger, Rad18-type putative)
19	K02F3.9	K02F3.9	n/a	chrIII 840,905
20	ZK287.3	ZK287.3	n/a	chrV 9,678,756	contains similarity to Rhodopirellula baltica Probable DEAH ATP-dependent helicase.; TR:Q7UYP6
21	cal-2	C18E9.1	n/a	chrII 8,961,053	cal-2 encodes a calmodulin homolog required for embryonic development or viability; CAL-2 is closely similar to its paralogs CAL-1, CAL-3, CAL-4 and CMD-1.
22	cyp-32A1	C26F1.2	n/a	chrV 7,783,180	C. elegans CYP-32A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR000897 (Signal recognition particle, SRP54 subunit, GTPase), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
23	K03D3.2	K03D3.2	n/a	chrIV 16,328,334	contains similarity to Sulfolobus tokodaii Hypothetical protein ST0074.; TR:Q976W5
24	F02H6.5	F02H6.5	n/a	chrIV 14,222,125	contains similarity to Pfam domain PF07992 Pyridine nucleotide-disulphide oxidoreductase contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR015904 (Sulphide quinone-reductase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
25	clc-1	C09F12.1	n/a	chrX 11,048,302	clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes; clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva; in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions.
26	K09H9.5	K09H9.5	n/a	chrI 3,142,441	contains similarity to Interpro domain IPR016638 (Uncharacterised conserved protein UPF0376)
27	srg-23	Y25C1A.11	n/a	chrII 3,095,026	C. elegans SRG-23 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
28	F57A10.2	F57A10.2	n/a	chrV 15,766,892	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
29	F12A10.2	F12A10.2	n/a	chrII 5,495,367
30	ttr-8	R13A5.6	n/a	chrIII 7,564,873	R13A5.6 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of R13A5.6 belongs to a family of apparently nematode-specific proteins whose function is not yet known; an R13A5.6::GFP promoter fusion directs expression outside of the nervous system.
31	T16G1.7	T16G1.7	n/a	chrV 12,933,975	T16G1.7 is orthologous to the human gene ALIAS DLC1~CANDIDATE TUMOR SUPPRESSOR GENE (DLEC1; OMIM:604050), which when mutated leads to disease.
32	cyp-34A7	B0213.12	n/a	chrV 3,962,772	C. elegans CYP-34A7 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
33	glc-1	F11A5.10	n/a	chrV 16,220,736	glc-1 encodes the alpha subunit of a glutamate-gated chloride channel and forms a functional channel in Xenopus oocytes; mutations genetically interact with avr-14 and avr-15 mutations such that triple mutants exhibit high level resistance to ivermectin.
34	F23F1.7	F23F1.7	n/a	chrII 39,046	contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
35	F48C1.8	F48C1.8	n/a	chrI 5,335,938	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein)
36	pqn-97	ZK488.10	n/a	chrV 609,465	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
37	pah-1	K08F8.4	n/a	chrII 8,763,866	pah-1 encodes a biochemically active phenylalanine-4-hydroxylase orthologous to human PAH (OMIM:261600, mutated in phenylketonuria); recombinant PAH-1 has hydroxylase activity on phenylalanine and tryptophan substrates in vitro; pah-1 is expressed in seam cells, tail hypodermal cells, and ventral hypodermis, with stronger posterior than anterior expression; PAH-1 might help provide tyrosine for cross-linking in the cuticle, and is partially required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
38	F35E2.6	F35E2.6	n/a	chrI 11,709,997	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
39	col-50	T28F2.6	n/a	chrI 3,651,949	col-50 encodes a cuticle collagen.
40	C49G9.1	C49G9.1	n/a	chrI 12,565,152	contains similarity to Fugu rubripes Wilms tumour gene.; TR:O93433
41	C47E12.9	C47E12.9	n/a	chrIV 9,975,041	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000265840
42	Y43F8B.9	Y43F8B.9	n/a	chrV 19,479,769
43	ins-4	ZK75.1	n/a	chrII 5,996,546	ins-4 encodes an insulin-like peptide.
44	F15D4.3	F15D4.3	n/a	chrII 13,237,564	contains similarity to Homo sapiens Protein MGR2 homolog; ENSEMBL:ENSP00000338293
45	F18G5.6	F18G5.6	n/a	chrX 9,263,128
46	F53A9.6	F53A9.6	n/a	chrX 8,713,583	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen)
47	C54D2.2	C54D2.2	n/a	chrX 7,839,011
48	T04A11.5	T04A11.5	n/a	chrIV 12,485,693	contains similarity to Pfam domain PF02567 Phenazine biosynthesis-like protein contains similarity to Interpro domain IPR003719 (Phenazine biosynthesis PhzC/PhzF protein)
49	C13A10.2	C13A10.2	n/a	chrII 1,357,598
50	srz-54	Y102A5C.25	n/a	chrV 16,981,243	C. elegans SRZ-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)