UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cnc-2	R09B5.3	0.003	chrV 1,449,921	cnc-2 encodes one of six C. elegans caenacin peptides; cnc-2 expression is strongly induced after infection by the fungus Drechmeria coniospora and the gram-negative bacteria Serratia marcescens, suggesting that it functions as a secreted antimicrobial peptide in the innate immune response.
2	grd-4	T01B10.1	n/a	chrX 8,501,684	grd-4 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-4 is weakly required for normal molting; GRD-4 is also required for normal adult alae formation, growth to full size, and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
3	F15E6.3	F15E6.3	n/a	chrIV 4,295,274	contains similarity to Cryptococcus neoformans Glycine-rich RNA binding protein, putative.; TR:Q5KDS6
4	dct-7	F15E6.8	n/a	chrIV 4,290,416	C. elegans DCT-7 protein ;
5	fipr-24	C37A5.8	n/a	chrI 14,157,799	C. elegans FIPR-24 protein ;
6	nlp-29	B0213.4	n/a	chrV 3,984,616	nlp-29 encodes a neuropeptide-like protein; nlp-29 appears to play a role in innate immunity, as its expression is strongly induced following bacterial and fungal infection; nlp-29 is expressed in the hypodermis and in the intestine; nlp-29 expression is regulated by TIR-1, an ortholog of SARM, a Toll-interleukin 1 receptor (TIR) domain protein, and by the RAB-1 GTPase and the product of R53.4, a mitochondrial ATP synthase subunit f homolog.
7	cpr-2	F36D3.9	n/a	chrV 16,533,516	C. elegans CPR-2 protein; contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
8	hsp-12.3	F38E11.1	n/a	chrIV 9,445,065	hsp-12.3 encodes a small heat-shock protein that forms heterotetramers with HSP-12.2 and has no chaperone-like activity; structurally, HSP-12.3 is mostly a beta-sheet; at least one HSP-12 (which may or may not be HSP-12.2) is ubiquitously expressed in L1 larvae, and later expressed in adult spermatids (and perhaps spermatocytes), and some adult vulval cells; hsp-12.3 is upregulated in daf-2 mutants, suggesting that hsp-12.3's expression may contribute to prolonged lifespan in dauer larvae.
9	F22B5.4	F22B5.4	n/a	chrII 8,451,121	contains similarity to Pseudomonas putida Butylphenol hydroxylase component A1.; TR:Q842G6
10	F16B4.7	F16B4.7	n/a	chrV 1,585,902	contains similarity to Drosophila melanogaster Flybase gene name is CG7294-PA;; FLYBASE:CG7294
11	ora-1	F57H12.3	n/a	chrIV 7,978,407	C. elegans ORA-1 protein ; contains similarity to Onchocerca volvulus OV39 antigen (Fragment).; SW:P31730
12	acs-2	F28F8.2	n/a	chrV 15,568,615	C. elegans ACS-2 protein; contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
13	T20D4.11	T20D4.11	n/a	chrV 3,399,039	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
14	grl-19	R02D3.6	n/a	chrIV 252,252	grl-19 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-19 is expressed in intestine; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
15	scl-11	F49E11.6	n/a	chrIV 13,051,732	C. elegans SCL-11 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
16	C30F12.3	C30F12.3	n/a	chrI 6,971,092
17	E04F6.9	E04F6.9	n/a	chrII 7,211,856
18	nlp-35	C33A12.2	n/a	chrIV 9,518,633	C. elegans NLP-35 protein ;
19	ZK970.7	ZK970.7	n/a	chrII 10,312,538	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
20	F09F7.6	F09F7.6	n/a	chrIII 5,551,674
21	C33G8.3	C33G8.3	n/a	chrV 7,007,900	contains similarity to Interpro domain IPR009149 (BR22)
22	ZK971.1	ZK971.1	n/a	chrII 10,279,516	contains similarity to Arabidopsis thaliana Gb\|AAB67622.1.; TR:Q9LT65
23	fip-1	F22B7.4	n/a	chrIII 8,639,817	C. elegans FIP-1 protein ; contains similarity to Homo sapiens Isoform A2 of Heterogeneous nuclear ribonucleoproteins A2/B1; ENSEMBL:ENSP00000354021
24	F53A9.1	F53A9.1	n/a	chrX 8,711,652	contains similarity to Interpro domains IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR002395 (HMW kininogen)
25	col-35	C15A11.1	n/a	chrI 7,386,359	col-35 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens; the amino- and carboxyl-terminal cysteine-rich regions of COL-35 are most closely related to those of COL-8, COL-19, and COL-39.
26	F22B7.9	F22B7.9	n/a	chrIII 8,653,148
27	C34C6.7	C34C6.7	n/a	chrII 8,707,892	contains similarity to Interpro domain IPR000533 (Tropomyosin)
28	F55G1.7	F55G1.7	n/a	chrIV 7,467,673
29	F14F11.2	F14F11.2	n/a	chrII 8,295,048	contains similarity to Rhodopirellula baltica Methanol dehydrogenase regulatory protein (EC 1.1.1.244).; TR:Q7UX83
30	F40G12.5	F40G12.5	n/a	chrV 14,269,931	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
31	C35C5.9	C35C5.9	n/a	chrX 11,536,770	contains similarity to Haemophilus influenzae Monofunctional biosynthetic peptidoglycan transglycosylases(EC 2.4.2.-) (Monofunctional TGase).; SW:MTGA_HAEIN
32	T24F1.5	T24F1.5	n/a	chrII 11,319,376	contains similarity to Bombyx mori Lebocin 1/2 precursor.; SW:LEB1_BOMMO
33	grl-17	C56A3.1	n/a	chrV 13,562,991	grl-17 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-17 is expressed in pharynx, rectal epithelium, amphid socket cells, larval arcade cells, and larval hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
34	nlp-12	M01D7.5	n/a	chrI 1,843,618	nlp-12 encodes two predicted neuropeptide-like proteins; nlp-12 is part of a LQFamide neuropeptide family that has members in at least one other nematode species; nlp-12 is expressed in one tail neuron; as loss of nlp-12 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-12-encoded peptides in development and/or behavior is not yet known.
35	F47B8.2	F47B8.2	n/a	chrV 14,316,299	contains similarity to Lyngbya lagerheimii CP 43 protein (Fragment).; TR:Q937F7
36	B0507.8	B0507.8	n/a	chrV 8,761,695	contains similarity to Schizosaccharomyces pombe Nucleoporin nup211 (Nuclear pore protein nup211).; SW:O74424
37	W06G6.11	W06G6.11	n/a	chrV 16,648,635	contains similarity to Mus musculus Calsyntenin-1 precursor.; SW:CLS1_MOUSE
38	T28A11.19	T28A11.19	n/a	chrV 3,269,156	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
39	ftn-1	C54F6.14	n/a	chrV 7,547,023	ftn-1 encodes one of two C. elegans ferritin heavy chain homologs; ftn-1 activity is essential for normal lifespan under iron stress conditions and, in addition, has been reported to be essential for embryogenesis; an ftn-1::gfp reporter is expressed in the intestine at all stages of development and its expression, as well as that of ftn-1 mRNA, increases under iron stress conditions and in the background of mutations in the second ferritin-encoding gene, ftn-2.
40	F56H9.2	F56H9.2	n/a	chrV 12,637,872	contains similarity to Plasmodium falciparum Transport protein, putative.; TR:Q8IHR3
41	Y73F4A.3	Y73F4A.3	n/a	chrIV 9,040,014	contains similarity to Pfam domain PF03351 DOMON domain contains similarity to Interpro domains IPR005018 (DOMON related), IPR008960 (Carbohydrate-binding family 9/cellobiose dehydrogenase, cytochrome), IPR013050 (DOMON)
42	nlp-32	F30H5.2	n/a	chrIII 486,349	C. elegans NLP-32 protein; contains similarity to Interpro domain IPR002952 (Eggshell protein)
43	F21C10.10	F21C10.10	n/a	chrV 9,096,675	contains similarity to Interpro domain IPR016040 (NAD(P)-binding)
44	clec-98	ZK39.7	n/a	chrI 11,154,783	C. elegans CLEC-98 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
45	F36D1.7	F36D1.7	n/a	chrI 11,263,396	contains similarity to Bacteriophage T5 L-shaped tail fiber protein (LTF protein).; SW:VLTF_BPT5
46	lact-6	C06A12.5	n/a	chrIV 17,430,817	lact-6 encodes a beta-lactamase domain-containing protein that contains a predicted signal sequence in its N terminus.
47	clec-97	ZK39.6	n/a	chrI 11,153,502	C. elegans CLEC-97 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
48	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
49	col-45	F53G12.7	n/a	chrI 116,588	col-45 encodes a cuticle collagen.
50	lys-3	Y22F5A.6	n/a	chrV 10,282,795	lys-3 encodes one of a family of ten C. elegans lysozyme genes that are homologous to lysozymes in the amoeboid protozoon Entamoeba histolytica.