UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srh-36	T03D3.4	0	chrV 2,820,623	C. elegans SRH-36 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
2	Y49E10.21	Y49E10.21	n/a	chrIII 12,458,332	contains similarity to Nanoarchaeum equitans DNA double-strand break repair rad50 ATPase.; SW:P62135
3	srx-135	F09F3.11	n/a	chrV 13,860,290	C. elegans SRX-135 protein ;
4	F21C10.6	F21C10.6	n/a	chrV 9,124,712	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
5	F36H12.2	F36H12.2	n/a	chrIV 5,275,375
6	T09B4.2	T09B4.2	n/a	chrI 6,184,694
7	wrn-1	F18C5.2	n/a	chrII 6,557,068	wrn-1 encodes an ortholog of human WRN, which when mutated leads to Werner syndrome (OMIM:277700), and one of four C. elegans homologs of the RecQ DNA helicase family that includes E. coli RecQ; by homology, WRN-1 is predicted to function as a helicase, DNA-dependent ATPase, and exonuclease that plays a key role in DNA replication, recombination, and repair; RNA interference studies in C. elegans and the enhancement of many of the resulting phenotypes by ionizing radiation indicate that wrn-1 affects life span and aging and acts at a DNA damage checkpoint; the wrn-1 phenotypes such as premature aging are similar to those of Werner syndrome; immunolocalization studies indicate that WRN-1 expression is nuclear in cells at the embryonic, larval and adult stages.
8	ZC412.8	ZC412.8	n/a	chrV 14,879,632	contains similarity to Plasmodium cynomolgi Circumsporozoite protein precursor (CS).; SW:P08675
9	Y65A5A.1	Y65A5A.1	n/a	chrIV 16,399,303	contains similarity to Interpro domain IPR001092 (Basic helix-loop-helix dimerization domain bHLH)
10	T27F6.4	T27F6.4	n/a	chrI 12,485,310	contains similarity to Saccharomyces cerevisiae Mid-Two Like 1; SGD:YGR023W
11	F54D10.4	F54D10.4	n/a	chrII 3,806,515
12	rab-39	D2013.1	n/a	chrII 9,322,411	rab-39 encodes a small, monomeric Rab GTPase that is most closely related to the human and Drosophila Rab39 GTPases; by homology, RAB-39 is predicted to function as a membrane-associated GTPase required for intracellular vesicular trafficking and for regulation of endo- and exocytosis; however, as loss of rab-39 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of RAB-39 in C. elegans development and/or behavior is not yet known.
13	F36D4.1	F36D4.1	n/a	chrV 9,418,520
14	srw-111	M01G12.4	n/a	chrI 12,124,188	C. elegans SRW-111 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
15	R160.2	R160.2	n/a	chrX 4,376,697
16	T01C8.3	T01C8.3	n/a	chrX 16,781,536
17	ZK218.1	ZK218.1	n/a	chrV 17,092,954	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
18	ZK402.1	ZK402.1	n/a	chrX 1,405,182
19	B0207.6	B0207.6	n/a	chrI 5,936,242	contains similarity to Pfam domain PF03029 Conserved hypothetical ATP binding protein contains similarity to Interpro domain IPR004130 (Protein of unknown function, ATP binding)
20	C48C5.3	C48C5.3	n/a	chrX 8,959,409	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
21	F40E3.3	F40E3.3	n/a	chrI 2,638,982
22	sra-11	F44F4.13	n/a	chrII 10,909,485	sra-11 encodes an orphan, G protein-coupled seven-transmembrane receptor; SRA-11 is expressed in three classes of interneurons, AIA, AIY, and AVB throughout larval and adult stages, and analysis of sra-11 mutations indicates that sra-11 activity in AIY is essential for olfactory imprinting; sra-11 expression in AIY is positively regulated by the TTX-3 and CEH-23 homeodomain proteins, with TTX-3 required for both initiation and maintenance of expression and CEH-23 required solely for maintenance.
23	F37B12.3	F37B12.3	n/a	chrII 9,040,539	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	btb-3	B0047.2	n/a	chrII 2,043,575	C. elegans BTB-3 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
25	C36F7.2	C36F7.2	n/a	chrI 9,551,413	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
26	C46E10.8	C46E10.8	n/a	chrII 3,726,646	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
27	clec-168	F38A1.7	n/a	chrIV 1,258,213	C. elegans CLEC-168 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
28	Y57G7A.8	Y57G7A.8	n/a	chrII 1,291,464
29	F28A10.5	F28A10.5	n/a	chrII 850,172	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
30	F56H6.4	F56H6.4	n/a	chrI 12,291,320	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
31	F20G4.2	F20G4.2	n/a	chrI 7,914,259	contains similarity to Saccharomyces cerevisiae Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; SGD:YER190W
32	nas-21	T11F9.5	n/a	chrV 11,473,207	nas-21 encodes an astacin-like metalloprotease.
33	B0564.2	B0564.2	n/a	chrIV 13,107,893	contains similarity to Pfam domain PF03171 2OG-Fe(II) oxygenase superfamily contains similarity to Interpro domain IPR005123 (2OG-Fe(II) oxygenase)
34	fbxa-145	F48C1.2	n/a	chrI 5,320,402	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
35	srd-21	W06G6.3	n/a	chrV 16,630,499	C. elegans SRD-21 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	Y39A1A.2	Y39A1A.2	n/a	chrIII 10,602,626	contains similarity to Oryza sativa Hypothetical protein.; TR:Q9LH25
37	F21H12.3	F21H12.3	n/a	chrII 6,082,723
38	F58E1.7	F58E1.7	n/a	chrII 1,678,353	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
39	D1014.2	D1014.2	n/a	chrV 8,145,287	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
40	W01H2.2	W01H2.2	n/a	chrX 4,218,344
41	grd-10	F09D12.1	n/a	chrIV 3,441,427	grd-10 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; GRD-10 is expressed in seam cells; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-10 is weakly required for normal molting; GRD-10 is also required for normal growth to full size and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
42	srw-94	H06H21.1	n/a	chrIV 4,815,890	C. elegans SRW-94 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
43	C06E4.5	C06E4.5	n/a	chrIV 7,255,611	contains similarity to Interpro domain IPR011009 (Protein kinase-like)
44	C54G10.1	C54G10.1	n/a	chrV 14,641,219	contains similarity to Homo sapiens similar to secreted gel-forming mucin; ENSEMBL:ENSP00000328427
45	F58E1.13	F58E1.13	n/a	chrII 1,695,343
46	csb-1	F53H4.1	n/a	chrX 15,863,557	csb-1 is orthologous to human gene ERCC6 (OMIM:133530, mutated in Cockayne syndrome); CSB-1 is required for embryonic viability, and represses UV-induced apoptosis in germ cells.
47	sdz-34	Y73C8C.7	n/a	chrV 3,108,727	C. elegans SDZ-34 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000533 (Tropomyosin), IPR011016 (Zinc finger, variant RING-type)
48	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
49	srj-26	ZK262.10	n/a	chrV 18,422,252	C. elegans SRJ-26 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	T07E3.3	T07E3.3	n/a	chrIII 6,904,401	contains similarity to Interpro domain IPR012336 (Thioredoxin-like fold)